| Tryptophan zippers: Stable, monomeric β-hairpins AG Cochran, NJ Skelton, MA Starovasnik Proceedings of the National Academy of Sciences 98 (10), 5578-5583, 2001 | 931 | 2001 |
| BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2 N Kayagaki, M Yan, D Seshasayee, H Wang, W Lee, DM French, ... Immunity 17 (4), 515-524, 2002 | 618 | 2002 |
| Bromodomains: a new target class for drug development AG Cochran, AR Conery, RJ Sims III Nature Reviews Drug Discovery 18 (8), 609-628, 2019 | 390 | 2019 |
| Antagonists of protein–protein interactions AG Cochran Chemistry & biology 7 (4), R85-R94, 2000 | 376 | 2000 |
| An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells M Vinogradova, VS Gehling, A Gustafson, S Arora, CA Tindell, C Wilson, ... Nature chemical biology 12 (7), 531-538, 2016 | 318 | 2016 |
| Reconstitution of a Frizzled8· Wnt3a· LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6 E Bourhis, C Tam, Y Franke, JF Bazan, J Ernst, J Hwang, M Costa, ... Journal of Biological Chemistry 285 (12), 9172-9179, 2010 | 284 | 2010 |
| Short constrained peptides that inhibit HIV-1 entry SK Sia, PA Carr, AG Cochran, VN Malashkevich, PS Kim Proceedings of the National Academy of Sciences 99 (23), 14664-14669, 2002 | 278 | 2002 |
| Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site WJ Fairbrother, HW Christinger, AG Cochran, G Fuh, CJ Keenan, C Quan, ... Biochemistry 37 (51), 17754-17764, 1998 | 256 | 1998 |
| Antibody-catalyzed porphyrin metallation AG Cochran, PG Schultz Science 249 (4970), 781-783, 1990 | 245 | 1990 |
| A subset of human bromodomains recognizes butyryllysine and crotonyllysine histone peptide modifications EM Flynn, OW Huang, F Poy, M Oppikofer, SF Bellon, Y Tang, ... Structure 23 (10), 1801-1814, 2015 | 216 | 2015 |
| Protein–protein interfaces: mimics and inhibitors AG Cochran Current Opinion in Chemical Biology 5 (6), 654-659, 2001 | 207 | 2001 |
| Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex ML Bentley, JE Corn, KC Dong, Q Phung, TK Cheung, AG Cochran The EMBO journal 30 (16), 3285-3297, 2011 | 177 | 2011 |
| A minimal peptide scaffold for β-turn display: optimizing a strand position in disulfide-cyclized β-hairpins AG Cochran, RT Tong, MA Starovasnik, EJ Park, RS McDowell, ... Journal of the American Chemical Society 123 (4), 625-632, 2001 | 174 | 2001 |
| Wnt antagonists bind through a short peptide to the first β-propeller domain of LRP5/6 E Bourhis, W Wang, C Tam, J Hwang, Y Zhang, D Spittler, OW Huang, ... Structure 19 (10), 1433-1442, 2011 | 166 | 2011 |
| A class of 2, 4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B I Aliagas-Martin, D Burdick, L Corson, J Dotson, J Drummond, C Fields, ... Journal of medicinal chemistry 52 (10), 3300-3307, 2009 | 155 | 2009 |
| Imitation of Escherichia coli Aspartate Receptor Signaling in Engineered Dimers of the Cytoplasmic Domain AG Cochran, PS Kim Science 271 (5252), 1113-1116, 1996 | 145 | 1996 |
| Stability of cyclic β-hairpins: Asymmetric contributions from side chains of a hydrogen-bonded cross-strand residue pair SJ Russell, T Blandl, NJ Skelton, AG Cochran Journal of the American Chemical Society 125 (2), 388-395, 2003 | 139 | 2003 |
| Peroxidase activity of an antibody-heme complex AG Cochran, PG Schultz Journal of the American Chemical Society 112 (25), 9414-9415, 1990 | 136 | 1990 |
| Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells S Rutz, N Kayagaki, QT Phung, C Eidenschenk, R Noubade, X Wang, ... Nature 518 (7539), 417-421, 2015 | 128 | 2015 |
| Phosphorylation-dependent activity of the deubiquitinase DUBA OW Huang, X Ma, JP Yin, J Flinders, T Maurer, N Kayagaki, Q Phung, ... Nature structural & molecular biology 19 (2), 171-175, 2012 | 128 | 2012 |
