| Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function DS Shouval, A Biswas, JA Goettel, K McCann, E Conaway, NS Redhu, ... Immunity 40 (5), 706-719, 2014 | 600 | 2014 |
| Haematopoietic stem and progenitor cells from human pluripotent stem cells R Sugimura, DK Jha, A Han, C Soria-Valles, EL Da Rocha, YF Lu, ... Nature 545 (7655), 432-438, 2017 | 504 | 2017 |
| Interleukin 10 receptor signaling: master regulator of intestinal mucosal homeostasis in mice and humans DS Shouval, J Ouahed, A Biswas, JA Goettel, BH Horwitz, C Klein, ... Advances in immunology 122, 177-210, 2014 | 370 | 2014 |
| AHR activation is protective against colitis driven by T cells in humanized mice JA Goettel, R Gandhi, JE Kenison, A Yeste, G Murugaiyan, ... Cell reports 17 (5), 1318-1329, 2016 | 188 | 2016 |
| Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps B Chen, S Cherie’R, ET McKinley, AJ Simmons, MA Ramirez-Solano, ... Cell 184 (26), 6262-6280. e26, 2021 | 176 | 2021 |
| Succinate produced by intestinal microbes promotes specification of tuft cells to suppress ileal inflammation A Banerjee, CA Herring, B Chen, H Kim, AJ Simmons, AN Southard-Smith, ... Gastroenterology 159 (6), 2101-2115. e5, 2020 | 165 | 2020 |
| Necrotising enterocolitis is characterised by disrupted immune regulation and diminished mucosal regulatory (FOXP3)/effector (CD4, CD8) T cell ratios JH Weitkamp, T Koyama, MT Rock, H Correa, JA Goettel, P Matta, ... Gut 62 (1), 73-82, 2013 | 158 | 2013 |
| Aquaporin-3 mediates hydrogen peroxide-dependent responses to environmental stress in colonic epithelia JR Thiagarajah, J Chang, JA Goettel, AS Verkman, WI Lencer Proceedings of the National Academy of Sciences 114 (3), 568-573, 2017 | 102 | 2017 |
| FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy WS Lexmond, JA Goettel, JJ Lyons, J Jacobse, MM Deken, MG Lawrence, ... The Journal of clinical investigation 126 (10), 4030-4044, 2016 | 61 | 2016 |
| TNF transactivation of EGFR stimulates cytoprotective COX-2 expression in gastrointestinal epithelial cells SS Hobbs, JA Goettel, D Liang, F Yan, KL Edelblum, MR Frey, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 301 (2 …, 2011 | 58 | 2011 |
| Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis G Ryzhakov, NR West, F Franchini, S Clare, NE Ilott, SN Sansom, ... Nature communications 9 (1), 3797, 2018 | 56 | 2018 |
| Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections Y Zhang, X Li, A Carpinteiro, JA Goettel, M Soddemann, E Gulbins Nature medicine 17 (3), 341-346, 2011 | 55 | 2011 |
| Ultrasound-mediated delivery of RNA to colonic mucosa of live mice CM Schoellhammer, GY Lauwers, JA Goettel, MA Oberli, C Cleveland, ... Gastroenterology 152 (5), 1151-1160, 2017 | 54 | 2017 |
| Intestinal regulatory T cells as specialized tissue-restricted immune cells in intestinal immune homeostasis and disease J Jacobse, J Li, EHHM Rings, JN Samsom, JA Goettel Frontiers in Immunology 12, 716499, 2021 | 53 | 2021 |
| WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis A Biswas, DS Shouval, A Griffith, JA Goettel, M Field, YH Kang, ... Nature communications 9 (1), 1779, 2018 | 49 | 2018 |
| TNFR1 Promotes Tumor Necrosis Factor-mediated Mouse Colon Epithelial Cell Survival through RAF Activation of NF-κB∗ KL Edelblum, JA Goettel, T Koyama, SJ McElroy, F Yan, DB Polk Journal of Biological Chemistry 283 (43), 29485-29494, 2008 | 45 | 2008 |
| Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3 JA Goettel, S Biswas, WS Lexmond, A Yeste, L Passerini, B Patel, S Yang, ... Blood, The Journal of the American Society of Hematology 125 (25), 3886-3895, 2015 | 43 | 2015 |
| Wiskott–Aldrich syndrome protein deficiency in innate immune cells leads to mucosal immune dysregulation and colitis in mice DD Nguyen, MA Wurbel, JA Goettel, MA Eston, OS Ahmed, R Marin, ... Gastroenterology 143 (3), 719-729. e2, 2012 | 39 | 2012 |
| Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor NS Redhu, V Bakthavatchalu, EA Conaway, DS Shouval, A Tsou, ... Elife 6, e27652, 2017 | 36 | 2017 |
| Aminoglycoside-mediated relaxation of the ductus arteriosus in sepsis-associated PDA MM Vucovich, RB Cotton, EL Shelton, JA Goettel, NJ Ehinger, SD Poole, ... American Journal of Physiology-Heart and Circulatory Physiology 307 (5 …, 2014 | 36 | 2014 |
