| Proline-based allosteric inhibitors of Zika and Dengue virus NS2B/NS3 proteases B Millies, F von Hammerstein, A Gellert, S Hammerschmidt, F Barthels, ... Journal of medicinal chemistry 62 (24), 11359-11382, 2019 | 76 | 2019 |
| FINDUS: An open-source 3D printable liquid-handling workstation for laboratory automation in life sciences F Barthels, U Barthels, M Schwickert, T Schirmeister SLAS TECHNOLOGY: Translating Life Sciences Innovation 25 (2), 190-199, 2020 | 48 | 2020 |
| Identification of sortase substrates by specificity profiling L Schmohl, J Bierlmeier, N von Kügelgen, L Kurz, P Reis, F Barthels, ... Bioorganic & Medicinal Chemistry 25 (18), 5002-5007, 2017 | 38 | 2017 |
| SAR of novel benzothiazoles targeting an allosteric pocket of DENV and ZIKV NS2B/NS3 proteases H Maus, F Barthels, SJ Hammerschmidt, K Kopp, B Millies, A Gellert, ... Bioorganic & medicinal chemistry 47, 116392, 2021 | 32 | 2021 |
| Naphthoquinones as covalent reversible inhibitors of cysteine proteases—studies on inhibition mechanism and kinetics P Klein, F Barthels, P Johe, A Wagner, S Tenzer, U Distler, TA Le, ... Molecules 25 (9), 2064, 2020 | 32 | 2020 |
| Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A F Barthels, G Marincola, T Marciniak, M Konhäuser, S Hammerschmidt, ... ChemMedChem 15 (10), 839-850, 2020 | 29 | 2020 |
| New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and Unexpected Prodrug Identification for the Trypanosoma Protease Rhodesain P Klein, P Johe, A Wagner, S Jung, J Kühlborn, F Barthels, S Tenzer, ... Molecules 25 (6), 1451, 2020 | 29 | 2020 |
| Fluorovinylsulfones and-sulfonates as potent covalent reversible inhibitors of the trypanosomal cysteine protease rhodesain: structure–activity relationship, inhibition … S Jung, N Fuchs, P Johe, A Wagner, E Diehl, T Yuliani, C Zimmer, ... Journal of Medicinal Chemistry 64 (16), 12322-12358, 2021 | 28 | 2021 |
| BANΔIT: B’‐factor analysis for drug design and structural biology F Barthels, T Schirmeister, C Kersten Molecular Informatics 40 (1), 2000144, 2021 | 28 | 2021 |
| Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening GP Volynets, F Barthels, SJ Hammerschmidt, OV Moshynets, ... The Journal of antibiotics 75 (6), 321-332, 2022 | 13 | 2022 |
| Investigation of the influence of chirality and halogen atoms on the anticancer activity of enantiopure palladium (II) complexes derived from chiral amino-alcohol Schiff bases … HA Rudbari, N Kordestani, JV Cuevas-Vicario, M Zhou, T Efferth, I Correia, ... New Journal of Chemistry 46 (14), 6470-6483, 2022 | 13 | 2022 |
| Hic sunt dracones: molecular docking in uncharted territories with structures from AlphaFold2 and RoseTTAfold C Kersten, S Clower, F Barthels Journal of Chemical Information and Modeling 63 (7), 2218-2225, 2023 | 10 | 2023 |
| 2-Sulfonylpyrimidines as Privileged Warheads for the Development of S. aureus Sortase A Inhibitors F Barthels, J Meyr, SJ Hammerschmidt, T Marciniak, HJ Räder, W Ziebuhr, ... Frontiers in Molecular Biosciences 8, 804970, 2022 | 9 | 2022 |
| Impact of the recognition part of dipeptidyl nitroalkene compounds on the inhibition mechanism of cysteine proteases cruzain and cathepsin L K Arafet, S Royo, T Schirmeister, F Barthels, FV González, V Moliner ACS catalysis 13 (9), 6289-6300, 2023 | 5 | 2023 |
| A low-cost 3D-printable differential scanning fluorometer for protein and RNA melting experiments F Barthels, SJ Hammerschmidt, TR Fischer, C Zimmer, E Kallert, M Helm, ... HardwareX 11, e00256, 2022 | 4 | 2022 |
| Modular solid-phase synthesis of antiprotozoal barnesin derivatives D Roman, L Raguz, F Keiff, F Meyer, F Barthels, T Schirmeister, F Kloss, ... Organic Letters 22 (10), 3744-3748, 2020 | 4 | 2020 |
| Advanced Isothermal Titration Calorimetry for Medicinal Chemists with ITCcalc SJ Hammerschmidt, F Barthels, AC Weldert, C Kersten Journal of Chemical Education 101 (3), 1086-1095, 2024 | 2 | 2024 |
| Impact of the Warhead of Dipeptidyl Keto Michael Acceptors on the Inhibition Mechanism of Cysteine Protease Cathepsin L A Fernández-de-la-Pradilla, S Royo, T Schirmeister, F Barthels, ... ACS catalysis 13 (20), 13354-13368, 2023 | 2 | 2023 |
| Next Generation of Fluorometric Protease Assays: 7‐Nitrobenz‐2‐oxa‐1, 3‐diazol‐4‐yl‐amides (NBD‐Amides) as Class‐Spanning Protease Substrates H Maus, P Müller, M Meta, SN Hoba, SJ Hammerschmidt, ... Chemistry–A European Journal 29 (50), e202301855, 2023 | 2 | 2023 |
| The effects of allosteric and competitive inhibitors on ZIKV protease conformational dynamics explored through smFRET, nanoDSF, DSF, and 19F NMR H Maus, SJ Hammerschmidt, G Hinze, F Barthels, VHP Carrillo, ... European Journal of Medicinal Chemistry 258, 115573, 2023 | 1 | 2023 |
