What recent ribosome structures have revealed about the mechanism of translation TM Schmeing, V Ramakrishnan Nature 461 (7268), 1234-1242, 2009 | 927 | 2009 |
The kink‐turn: a new RNA secondary structure motif DJ Klein, TM Schmeing, PB Moore, TA Steitz The EMBO journal, 2001 | 919 | 2001 |
The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA TM Schmeing, RM Voorhees, AC Kelley, YG Gao, FV Murphy IV, JR Weir, ... Science 326 (5953), 688-694, 2009 | 587 | 2009 |
An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA T Martin Schmeing, KS Huang, SA Strobel, TA Steitz Nature 438 (7067), 520-524, 2005 | 445 | 2005 |
The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome LA Passmore, TM Schmeing, D Maag, DJ Applefield, MG Acker, MA Algire, ... Molecular cell 26 (1), 41-50, 2007 | 435 | 2007 |
The mechanism for activation of GTP hydrolysis on the ribosome RM Voorhees, TM Schmeing, AC Kelley, V Ramakrishnan Science 330 (6005), 835-838, 2010 | 406 | 2010 |
Structural insights into peptide bond formation JL Hansen, TM Schmeing, PB Moore, TA Steitz Proceedings of the National Academy of Sciences 99 (18), 11670-11675, 2002 | 364 | 2002 |
Structural insights into the roles of water and the 2′ hydroxyl of the P site tRNA in the peptidyl transferase reaction TM Schmeing, KS Huang, DE Kitchen, SA Strobel, TA Steitz Molecular cell 20 (3), 437-448, 2005 | 321 | 2005 |
A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits TM Schmeing, AC Seila, JL Hansen, B Freeborn, JK Soukup, SA Scaringe, ... Nature structural biology 9 (3), 225-230, 2002 | 264 | 2002 |
Structural and functional aspects of the nonribosomal peptide synthetase condensation domain superfamily: discovery, dissection and diversity K Bloudoff, TM Schmeing Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1865 (11), 1587-1604, 2017 | 214 | 2017 |
Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase JM Reimer, MN Aloise, PM Harrison, T Martin Schmeing Nature 529 (7585), 239-242, 2016 | 176 | 2016 |
Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage R Cencic, H Miura, A Malina, F Robert, S Ethier, TM Schmeing, J Dostie, ... PloS one 9 (10), e109213, 2014 | 160 | 2014 |
How mutations in tRNA distant from the anticodon affect the fidelity of decoding TM Schmeing, RM Voorhees, AC Kelley, V Ramakrishnan Nature structural & molecular biology 18 (4), 432-436, 2011 | 155 | 2011 |
Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit TM Schmeing, PB Moore, TA Steitz Rna 9 (11), 1345-1352, 2003 | 114 | 2003 |
Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility JM Reimer, M Eivaskhani, I Harb, A Guarné, M Weigt, TM Schmeing Science 366 (6466), eaaw4388, 2019 | 112 | 2019 |
X-ray crystallography and electron microscopy of cross-and multi-module nonribosomal peptide synthetase proteins reveal a flexible architecture MJ Tarry, AS Haque, KH Bui, TM Schmeing Structure 25 (5), 783-793. e4, 2017 | 110 | 2017 |
Trapping biosynthetic acyl-enzyme intermediates with encoded 2, 3-diaminopropionic acid N Huguenin-Dezot, DA Alonzo, GW Heberlig, M Mahesh, DP Nguyen, ... Nature 565 (7737), 112-117, 2019 | 107 | 2019 |
Crystal structures of the first condensation domain of CDA synthetase suggest conformational changes during the synthetic cycle of nonribosomal peptide synthetases K Bloudoff, D Rodionov, TM Schmeing Journal of molecular biology 425 (17), 3137-3150, 2013 | 104 | 2013 |
Piecing together nonribosomal peptide synthesis JM Reimer, AS Haque, MJ Tarry, TM Schmeing Current opinion in structural biology 49, 104-113, 2018 | 101 | 2018 |
Genomic organization of the canine p53 gene and its mutational status in canine mammary neoplasia LL Chu, GR Rutteman, JMC Kong, M Ghahremani, M Schmeing, ... Breast cancer research and treatment 50, 11-25, 1998 | 92 | 1998 |