Structural basis of the activation of a metabotropic GABA receptor H Shaye, A Ishchenko, JH Lam, GW Han, L Xue, P Rondard, JP Pin, ... Nature 584 (7820), 298-303, 2020 | 108 | 2020 |
A deep learning framework to predict binding preference of RNA constituents on protein surface JH Lam, Y Li, L Zhu, R Umarov, H Jiang, A Héliou, FK Sheong, T Liu, ... Nature communications 10 (1), 4941, 2019 | 89 | 2019 |
Self-assembling tetrameric peptides allow in situ 3D bioprinting under physiological conditions S Rauf, HH Susapto, K Kahin, S Alshehri, S Abdelrahman, JH Lam, ... Journal of Materials Chemistry B 9 (4), 1069-1081, 2021 | 56 | 2021 |
Structural basis of GABA reuptake inhibition Z Motiwala, NG Aduri, H Shaye, GW Han, JH Lam, V Katritch, V Cherezov, ... Nature 606 (7915), 820-826, 2022 | 52 | 2022 |
Ligand and G-protein selectivity in the κ-opioid receptor J Han, J Zhang, AL Nazarova, SM Bernhard, BE Krumm, L Zhao, JH Lam, ... Nature 617 (7960), 417-425, 2023 | 31 | 2023 |
Structural details of a Class B GPCR-arrestin complex revealed by genetically encoded crosslinkers in living cells Y Aydin, T Böttke, JH Lam, S Ernicke, A Fortmann, M Tretbar, B Zarzycka, ... Nature Communications 14 (1), 1151, 2023 | 21 | 2023 |
Structure of the full-length human Pannexin1 channel and insights into its role in pyroptosis S Zhang, B Yuan, JH Lam, J Zhou, X Zhou, G Ramos-Mandujano, X Tian, ... Cell Discovery 7 (1), 30, 2021 | 19 | 2021 |
Constitutive activation mechanism of a class C GPCR J Shin, J Park, J Jeong, JH Lam, X Qiu, D Wu, K Kim, JY Lee, ... Nature Structural & Molecular Biology 31 (4), 678-687, 2024 | 2 | 2024 |
The Functional Diversity of G Proteins in Opioid Receptor Signaling T Che, Q Jiang, J Han, J Zhang, A Nazarova, SM Bernhard, BE Krumm, ... Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024 | | 2024 |
Efficacy modulation by targeting the sodium binding allosteric site in the delta opioid receptor BR Varga, SM Bernhard, A El Daibani, S Zaidi, J Aquilar, A Nazarova, ... Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024 | | 2024 |
Scalable computation of anisotropic vibrations for large macromolecular assemblies JH Lam, A Nakano, V Katritch Nature Communications 15 (1), 3479, 2024 | | 2024 |
Structure, Function, and Pharmacology of Delta Opioid Receptor Bitopics S Bernhard, BR Varga, A El Daibani, JH Lam, S Zaidi, K Appourchaux, ... Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |