Auranofin, Et3PAuCl, and Et3PAuI Are Highly Cytotoxic on Colorectal Cancer Cells: A Chemical and Biological Study T Marzo, D Cirri, C Gabbiani, T Gamberi, F Magherini, A Pratesi, A Guerri, ... ACS Medicinal Chemistry Letters 8 (10), 997-1001, 2017 | 106 | 2017 |
Metallo therapeutics for COVID-19. Exploiting metal-based compounds for the discovery of new antiviral drugs D Cirri, A Pratesi, T Marzo, L Messori Expert opinion on drug discovery 16 (1), 39-46, 2021 | 73 | 2021 |
Auranofin and its analogues show potent antimicrobial activity against multidrug‐resistant pathogens: structure–activity relationships T Marzo, D Cirri, S Pollini, M Prato, S Fallani, MI Cassetta, A Novelli, ... ChemMedChem 13 (22), 2448-2454, 2018 | 73 | 2018 |
Replacement of the thiosugar of auranofin with iodide enhances the anticancer potency in a mouse model of ovarian cancer T Marzo, L Massai, A Pratesi, M Stefanini, D Cirri, F Magherini, M Becatti, ... ACS Medicinal Chemistry Letters 10 (4), 656-660, 2019 | 69 | 2019 |
Strategies for the improvement of metal-based chemotherapeutic treatments D Cirri, F Bartoli, A Pratesi, E Baglini, E Barresi, T Marzo Biomedicines 9 (5), 504, 2021 | 48 | 2021 |
Reactions of medicinal gold (III) compounds with proteins and peptides explored by electrospray ionization mass spectrometry and complementary biophysical methods L Massai, C Zoppi, D Cirri, A Pratesi, L Messori Frontiers in Chemistry 8, 581648, 2020 | 47 | 2020 |
Reactions of auranofin and its pseudohalide derivatives with serum albumin investigated through ESI-Q-TOF MS A Pratesi, D Cirri, L Ciofi, L Messori Inorganic Chemistry 57 (17), 10507-10510, 2018 | 47 | 2018 |
PtI 2 (DACH), the iodido analogue of oxaliplatin as a candidate for colorectal cancer treatment: chemical and biological features D Cirri, S Pillozzi, C Gabbiani, J Tricomi, G Bartoli, M Stefanini, ... Dalton Transactions 46 (10), 3311-3317, 2017 | 45 | 2017 |
A fluorescent silver (I) carbene complex with anticancer properties: synthesis, characterization, and biological studies MG Fabbrini, D Cirri, A Pratesi, L Ciofi, T Marzo, A Guerri, S Nistri, ... ChemMedChem 14 (1), 182-188, 2019 | 44 | 2019 |
Structure-activity relationships in a series of auranofin analogues showing remarkable antiproliferative properties I Landini, L Massai, D Cirri, T Gamberi, P Paoli, L Messori, E Mini, S Nobili Journal of Inorganic Biochemistry 208, 111079, 2020 | 40 | 2020 |
Structural characterization of a gold/serum albumin complex A Pratesi, D Cirri, D Fregona, G Ferraro, A Giorgio, A Merlino, L Messori Inorganic Chemistry 58 (16), 10616-10619, 2019 | 39 | 2019 |
Mechanistic Insights Into the Anticancer Properties of the Auranofin Analog Au(PEt3)I: A Theoretical and Experimental Study I Tolbatov, D Cirri, L Marchetti, A Marrone, C Coletti, N Re, D La Mendola, ... Frontiers in Chemistry 8, 812, 2020 | 34 | 2020 |
New gold carbene complexes as candidate anticancer agents A Pratesi, D Cirri, MD Đurović, S Pillozzi, G Petroni, ŽD Bugarčić, ... Biometals 29, 905-911, 2016 | 28 | 2016 |
Reactions of cisplatin and cis-[PtI2 (NH3) 2] with molecular models of relevant protein sidechains: A comparative analysis I Tolbatov, T Marzo, D Cirri, C Gabbiani, C Coletti, A Marrone, R Paciotti, ... Journal of inorganic biochemistry 209, 111096, 2020 | 25 | 2020 |
Organogold (III) compounds as experimental anticancer agents: chemical and biological profiles L Massai, D Cirri, E Michelucci, G Bartoli, A Guerri, MA Cinellu, F Cocco, ... BioMetals 29, 863-872, 2016 | 22 | 2016 |
In vitro anti-SARS-CoV-2 activity of selected metal compounds and potential molecular basis for their actions based on computational study D Cirri, T Marzo, I Tolbatov, A Marrone, F Saladini, I Vicenti, F Dragoni, ... Biomolecules 11 (12), 1858, 2021 | 19 | 2021 |
On the Different Mode of Action of Au (I)/Ag (I)-NHC Bis-Anthracenyl Complexes Towards Selected Target Biomolecules F Binacchi, F Guarra, D Cirri, T Marzo, A Pratesi, L Messori, C Gabbiani, ... Molecules 25 (22), 5446, 2020 | 19 | 2020 |
The leading established metal-based drugs: a revisitation of their relevant physico-chemical data D Cirri, MG Fabbrini, A Pratesi, L Ciofi, L Massai, T Marzo, L Messori BioMetals 32, 813-817, 2019 | 18 | 2019 |
Auranofin and its analogs as prospective agents for the treatment of colorectal cancer L Massai, D Cirri, T Marzo, L Messori Cancer Drug Resistance 5 (1), 1, 2022 | 16 | 2022 |
Reactions of a tetranuclear Pt-thiosemicarbazone complex with model proteins T Marzo, F Navas, D Cirri, A Merlino, G Ferraro, L Messori, AG Quiroga Journal of Inorganic Biochemistry 181, 11-17, 2018 | 16 | 2018 |