PCSK9 is a critical regulator of the innate immune response and septic shock outcome KR Walley, KR Thain, JA Russell, MP Reilly, NJ Meyer, JF Ferguson, ... Science translational medicine 6 (258), 258ra143-258ra143, 2014 | 331 | 2014 |
Microbiota composition and metabolism are associated with gut function in Parkinson's disease MS Cirstea, AC Yu, E Golz, K Sundvick, D Kliger, N Radisavljevic, ... Movement Disorders 35 (7), 1208-1217, 2020 | 249 | 2020 |
Decreased high-density lipoprotein cholesterol level is an early prognostic marker for organ dysfunction and death in patients with suspected sepsis M Cirstea, KR Walley, JA Russell, LR Brunham, KR Genga, JH Boyd Journal of critical care 38, 289-294, 2017 | 145 | 2017 |
Increased plasma PCSK9 levels are associated with reduced endotoxin clearance and the development of acute organ failures during sepsis JH Boyd, CD Fjell, JA Russell, D Sirounis, MS Cirstea, KR Walley Journal of Innate Immunity 8 (2), 211-220, 2016 | 123 | 2016 |
Lipopolysaccharide is cleared from the circulation by hepatocytes via the low density lipoprotein receptor E Topchiy, M Cirstea, HJJ Kong, JH Boyd, Y Wang, JA Russell, KR Walley PLoS One 11 (5), e0155030, 2016 | 113 | 2016 |
Cholesteryl ester transfer protein influences high-density lipoprotein levels and survival in sepsis M Trinder, KR Genga, HJJ Kong, LL Blauw, C Lo, X Li, M Cirstea, Y Wang, ... American journal of respiratory and critical care medicine 199 (7), 854-862, 2019 | 83 | 2019 |
Gut microbiome in Parkinson's disease: New insights from meta-analysis TS Toh, CW Chong, SY Lim, J Bowman, M Cirstea, CH Lin, CC Chen, ... Parkinsonism & related disorders 94, 1-9, 2022 | 76 | 2022 |
MIND and Mediterranean diets associated with later onset of Parkinson's disease A Metcalfe‐Roach, AC Yu, E Golz, M Cirstea, K Sundvick, D Kliger, ... Movement Disorders 36 (4), 977-984, 2021 | 75 | 2021 |
Good bug, bad bug: breaking through microbial stereotypes M Cirstea, N Radisavljevic, BB Finlay Cell Host & Microbe 23 (1), 10-13, 2018 | 70 | 2018 |
Two‐year follow‐up of patients with septic shock presenting with low HDL: the effect upon acute kidney injury, death and estimated glomerular filtration rate K Roveran Genga, C Lo, M Cirstea, G Zhou, KR Walley, JA Russell, ... Journal of internal medicine 281 (5), 518-529, 2017 | 47 | 2017 |
Impact of PCSK9 loss-of-function genotype on 1-year mortality and recurrent infection in sepsis survivors KR Genga, C Lo, MS Cirstea, FS Leitao Filho, KR Walley, JA Russell, ... EBioMedicine 38, 257-264, 2018 | 35 | 2018 |
Type VI secretion systems of pathogenic and commensal bacteria mediate niche occupancy in the gut A Serapio-Palacios, SE Woodward, SL Vogt, W Deng, A Creus-Cuadros, ... Cell Reports 39 (4), 2022 | 34 | 2022 |
Reduced Proprotein convertase subtilisin/kexin 9 (PCSK9) function increases lipoteichoic acid clearance and improves outcomes in Gram positive septic shock patients AKK Leung, KR Genga, E Topchiy, M Cirstea, T Shimada, C Fjell, ... Scientific reports 9 (1), 10588, 2019 | 32 | 2019 |
TNFAIP2 inhibits early TNFa-induced NF-κB signaling and decreases survival in septic shock patients SA Thair, E Topchiy, JH Boyd, M Cirstea, C Wang, T Nakada, CD Fjell, ... Journal of innate immunity 8 (1), 57-66, 2016 | 31 | 2016 |
Bacterial–fungal interactions in the neonatal gut influence asthma outcomes later in life RCT Boutin, C Petersen, SE Woodward, A Serapio-Palacios, ... Elife 10, e67740, 2021 | 30 | 2021 |
The oral and fecal microbiota in a Canadian cohort of Alzheimer’s disease MS Cirstea, D Kliger, AD MacLellan, AC Yu, J Langlois, M Fan, ... Journal of Alzheimer's Disease 87 (1), 247-258, 2022 | 26 | 2022 |
Cross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition KE Huus, TT Hoang, A Creus-Cuadros, M Cirstea, SL Vogt, ... Nature Communications 12 (1), 6860, 2021 | 24 | 2021 |
Bottoms up: the role of gut microbiota in brain health N Radisavljevic, M Cirstea, B Brett Finlay Environmental microbiology 21 (9), 3197-3211, 2019 | 23 | 2019 |
The gut mycobiome in Parkinson’s disease MS Cirstea, K Sundvick, E Golz, AC Yu, RCT Boutin, D Kliger, BB Finlay, ... Journal of Parkinson's Disease 11 (1), 153-158, 2021 | 22 | 2021 |
Gastric acid and escape to systemic circulation represent major bottlenecks to host infection by Citrobacter rodentium SE Woodward, SL Vogt, J Peña-Díaz, RA Melnyk, M Cirstea, ... The ISME Journal 17 (1), 36-46, 2023 | 10 | 2023 |