Critical nodes in signalling pathways: insights into insulin action CM Taniguchi, B Emanuelli, CR Kahn Nature reviews Molecular cell biology 7 (2), 85-96, 2006 | 3552 | 2006 |
SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-α in the adipose tissue of obese mice B Emanuelli, P Peraldi, C Filloux, C Chavey, K Freidinger, DJ Hilton, ... Journal of Biological Chemistry 276 (51), 47944-47949, 2001 | 634 | 2001 |
SOCS-3 is an insulin-induced negative regulator of insulin signaling B Emanuelli, P Peraldi, C Filloux, D Sawka-Verhelle, D Hilton, ... Journal of Biological Chemistry 275 (21), 15985-15991, 2000 | 597 | 2000 |
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production E Jing, B Emanuelli, MD Hirschey, J Boucher, KY Lee, D Lombard, ... Proceedings of the national academy of sciences 108 (35), 14608-14613, 2011 | 550 | 2011 |
Intrinsic differences in adipocyte precursor cells from different white fat depots Y Macotela, B Emanuelli, MA Mori, S Gesta, TJ Schulz, YH Tseng, ... Diabetes 61 (7), 1691-1699, 2012 | 364 | 2012 |
Dietary leucine-an environmental modifier of insulin resistance acting on multiple levels of metabolism Y Macotela, B Emanuelli, AM Bång, DO Espinoza, J Boucher, K Beebe, ... PloS one 6 (6), e21187, 2011 | 320 | 2011 |
Interplay between FGF21 and insulin action in the liver regulates metabolism B Emanuelli, SG Vienberg, G Smyth, C Cheng, KI Stanford, M Arumugam, ... The Journal of clinical investigation 124 (2), 515-527, 2014 | 295 | 2014 |
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance C Vernochet, A Mourier, O Bezy, Y Macotela, J Boucher, MJ Rardin, D An, ... Cell metabolism 16 (6), 765-776, 2012 | 256 | 2012 |
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans O Bezy, TT Tran, J Pihlajamäki, R Suzuki, B Emanuelli, J Winnay, MA Mori, ... The Journal of clinical investigation 121 (6), 2504-2517, 2011 | 175 | 2011 |
Surfing the insulin signaling web E Van Obberghen, V Baron, L Delahaye, B Emanuelli, N Filippa, ... European journal of clinical investigation 31 (11), 966-977, 2001 | 171 | 2001 |
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis EG Sustarsic, T Ma, MD Lynes, M Larsen, I Karavaeva, JF Havelund, ... Cell metabolism 28 (1), 159-174. e11, 2018 | 148 | 2018 |
Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance B Emanuelli, D Eberlé, R Suzuki, CR Kahn Proceedings of the National Academy of Sciences 105 (9), 3545-3550, 2008 | 134 | 2008 |
Cross-talk between insulin and Wnt signaling in preadipocytes role of WNT co-receptor low density lipoprotein receptor-related protein-5 (LRP5) J Palsgaard, B Emanuelli, JN Winnay, G Sumara, G Karsenty, CR Kahn Journal of Biological Chemistry 287 (15), 12016-12026, 2012 | 131 | 2012 |
CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice CH Wang, M Lundh, A Fu, R Kriszt, TL Huang, MD Lynes, LO Leiria, ... Science translational medicine 12 (558), eaaz8664, 2020 | 107 | 2020 |
Cross talk between insulin and bone morphogenetic protein signaling systems in brown adipogenesis H Zhang, TJ Schulz, DO Espinoza, TL Huang, B Emanuelli, K Kristiansen, ... Molecular and cellular biology 30 (17), 4224-4233, 2010 | 88 | 2010 |
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis OS Johansen, T Ma, JB Hansen, LK Markussen, R Schreiber, ... Cell 184 (13), 3502-3518. e33, 2021 | 87 | 2021 |
Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473 KV Tran, EL Brown, T DeSouza, NZ Jespersen, C Nandrup-Bus, Q Yang, ... Nature Metabolism 2 (5), 397-412, 2020 | 86 | 2020 |
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis F Shamsi, R Xue, TL Huang, M Lundh, Y Liu, LO Leiria, MD Lynes, ... Nature communications 11 (1), 1421, 2020 | 84 | 2020 |
Insulin induces suppressor of cytokine signaling-3 tyrosine phosphorylation through janus-activated kinase P Peraldi, C Filloux, B Emanuelli, DJ Hilton, E Van Obberghen Journal of Biological Chemistry 276 (27), 24614-24620, 2001 | 81 | 2001 |
The potential role of SOCS-3 in the interleukin-1β-induced desensitization of insulin signaling in pancreatic beta-cells B Emanuelli, M Glondu, C Filloux, P Peraldi, E Van Obberghen Diabetes 53 (suppl_3), S97-S103, 2004 | 73 | 2004 |