| Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology W Van Rheenen, RAA Van Der Spek, MK Bakker, JJFA Van Vugt, PJ Hop, ... Nature genetics 53 (12), 1636-1648, 2021 | 300 | 2021 |
| Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex GL Shireby, JP Davies, PT Francis, J Burrage, EM Walker, GWA Neilson, ... Brain 143 (12), 3763-3775, 2020 | 117 | 2020 |
| A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex RG Smith, E Pishva, G Shireby, AR Smith, JAY Roubroeks, E Hannon, ... Nature communications 12 (1), 3517, 2021 | 113 | 2021 |
| Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS PJ Hop, RAJ Zwamborn, E Hannon, GL Shireby, MF Nabais, EM Walker, ... Science translational medicine 14 (633), eabj0264, 2022 | 54 | 2022 |
| DNA methylation signatures of Alzheimer’s disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types G Shireby, EL Dempster, S Policicchio, RG Smith, E Pishva, B Chioza, ... Nature Communications 13 (1), 5620, 2022 | 44 | 2022 |
| The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes F Grodstein, B Lemos, L Yu, HU Klein, A Iatrou, AS Buchman, GL Shireby, ... Neurobiology of disease 157, 105428, 2021 | 42 | 2021 |
| Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons LC Steg, GL Shireby, J Imm, JP Davies, A Franklin, R Flynn, SC Namboori, ... Molecular brain 14 (1), 98, 2021 | 22 | 2021 |
| Epigenome-wide association study of attention-deficit/hyperactivity disorder in adults P Rovira, C Sánchez-Mora, M Pagerols, V Richarte, M Corrales, ... Translational psychiatry 10 (1), 199, 2020 | 22 | 2020 |
| Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology L Pihlstrøm, G Shireby, H Geut, SP Henriksen, AJM Rozemuller, ... Nature communications 13 (1), 4932, 2022 | 19 | 2022 |
| Machine learning-based prediction of cognitive outcomes in de novo Parkinson’s disease J Harvey, RA Reijnders, R Cavill, A Duits, S Köhler, L Eijssen, BPF Rutten, ... npj Parkinson's Disease 8 (1), 150, 2022 | 11 | 2022 |
| Genetic risk for Alzheimer’s disease influences neuropathology via multiple biological pathways E Hannon, GL Shireby, K Brookes, J Attems, R Sims, NJ Cairns, S Love, ... Brain Communications 2 (2), fcaa167, 2020 | 11 | 2020 |
| A comparison of blood and brain‐derived ageing and inflammation‐related DNA methylation signatures and their association with microglial burdens AJ Stevenson, DL McCartney, DA Gadd, G Shireby, RF Hillary, D King, ... European Journal of Neuroscience 56 (9), 5637-5649, 2022 | 10 | 2022 |
| Evaluation of nanopore sequencing for epigenetic epidemiology: a comparison with DNA methylation microarrays R Flynn, S Washer, AR Jeffries, A Andrayas, G Shireby, M Kumari, ... Human Molecular Genetics 31 (18), 3181-3190, 2022 | 9 | 2022 |
| Uncertainty quantification of reference-based cellular deconvolution algorithms DS Vellame, G Shireby, A MacCalman, EL Dempster, J Burrage, ... Epigenetics 18 (1), 2137659, 2023 | 7 | 2023 |
| Genome-wide study of DNA methylation in amyotrophic lateral sclerosis identifies differentially methylated loci and implicates metabolic, inflammatory and cholesterol pathways PJ Hop, RAJ Zwamborn, E Hannon, GL Shireby, MF Nabais, EM Walker, ... medRxiv, 2021.03. 12.21253115, 2021 | 7 | 2021 |
| Accelerated pace of aging in schizophrenia: five case-control studies A Caspi, G Shireby, J Mill, TE Moffitt, K Sugden, E Hannon Biological Psychiatry 95 (11), 1038-1047, 2024 | 5 | 2024 |
| Epigenetic age acceleration is associated with oligodendrocyte proportions in MSA and control brain tissue M Murthy, G Shireby, Y Miki, E Viré, T Lashley, TT Warner, J Mill, ... Neuropathology and Applied Neurobiology 49 (1), e12872, 2023 | 4 | 2023 |
| A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparison X Shen, M Barbu, D Caramaschi, R Arathimos, D Czamara, F David, ... medRxiv, 2023.10. 27.23297630, 2023 | 2 | 2023 |
| Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific … W van Rheenen, RAA van der Spek, MK Bakker, JJFA van Vugt, PJ Hop, ... Nature genetics 54 (3), 361-361, 2022 | 1 | 2022 |
| Novel epigenetic clock for fetal brain development predicts fetal epigenetic age for iPSCs and iPSC-derived neurons. LC Steg, GL Shireby, J Imm, JP Davies, R Flynn, SC Namboori, A Bhinge, ... | 1 | 2020 |
