Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol HYK Kaan, V Ulaganathan, O Rath, H Prokopcova, D Dallinger, ... Journal of medicinal chemistry 53 (15), 5676-5683, 2010 | 183 | 2010 |
An allosteric transition trapped in an intermediate state of a new kinesin–inhibitor complex HYK Kaan, V Ulaganathan, DD Hackney, F Kozielski Biochemical Journal 425 (1), 55-61, 2010 | 86 | 2010 |
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein V Ulaganathan, SK Talapatra, O Rath, A Pannifer, DD Hackney, ... Journal of the American Chemical Society 135 (6), 2263-2272, 2013 | 69 | 2013 |
Tackling drug resistance with efflux pump inhibitors: from bacteria to cancerous cells RC Lowrence, SG Subramaniapillai, V Ulaganathan, S Nagarajan Critical reviews in microbiology 45 (3), 334-353, 2019 | 62 | 2019 |
Structure–activity relationships and molecular docking of novel dihydropyrimidine‐based mitotic Eg5 inhibitors H Prokopcová, D Dallinger, G Uray, HYK Kaan, V Ulaganathan, ... ChemMedChem 5 (10), 1760-1769, 2010 | 61 | 2010 |
Structure−Activity Relationship and Multidrug Resistance Study of New S-trityl-l-Cysteine Derivatives As Inhibitors of Eg5 HYK Kaan, J Weiss, D Menger, V Ulaganathan, K Tkocz, C Laggner, ... Journal of medicinal chemistry 54 (6), 1576-1586, 2011 | 50 | 2011 |
Nucleotide substrate recognition by UDP-N-acetylglucosamine acyltransferase (LpxA) in the first step of lipid A biosynthesis V Ulaganathan, L Buetow, WN Hunter Journal of molecular biology 369 (2), 305-312, 2007 | 41 | 2007 |
Ferulic acid derivative inhibits NorA efflux and in combination with ciprofloxacin curtails growth of MRSA in vitro and in vivo NS Sundaramoorthy, K Mitra, JS Ganesh, H Makala, R Lotha, ... Microbial pathogenesis 124, 54-62, 2018 | 36 | 2018 |
Subtlety in the reactivity of a diketo phosphorus ylide towards mercuric halides: the unprecedented O-coordination of α-acetyl-α-benzoylmethylenetriphenylphosphorane to Hg (II) P Laavanya, U Venkatasubramanian, K Panchanatheswaran, JAK Bauer Chemical Communications, 1660-1661, 2001 | 35 | 2001 |
Dithiazole thione derivative as competitive NorA efflux pump inhibitor to curtail multi drug resistant clinical isolate of MRSA in a zebrafish infection model RC Lowrence, T Raman, HV Makala, V Ulaganathan, ... Applied microbiology and biotechnology 100, 9265-9281, 2016 | 34 | 2016 |
The crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal development M Klejnot, A Falnikar, V Ulaganathan, RA Cross, PW Baas, F Kozielski Acta Crystallographica Section D: Biological Crystallography 70 (1), 123-133, 2014 | 32 | 2014 |
The synthesis and molecular and crystal structures of 1-methyl-2-carboxy-1, 2-dicarba-closo-dodecaborane (12), 1-phenyl-2-carboxy-1, 2-dicarba-closo-dodecaborane (12) and 1 … U Venkatasubramanian, DJ Donohoe, D Ellis, BT Giles, SA Macgregor, ... Polyhedron 23 (4), 629-636, 2004 | 30 | 2004 |
A Structure-Based Approach to Ligand Discovery for 2C-Methyl-d-erythritol-2,4-cyclodiphosphate Synthase: A Target for Antimicrobial Therapy NL Ramsden, L Buetow, A Dawson, LA Kemp, V Ulaganathan, R Brenk, ... Journal of medicinal chemistry 52 (8), 2531-2542, 2009 | 29 | 2009 |
Structure of Staphylococcus aureus 1, 4-dihydroxy-2-naphthoyl-CoA synthase (MenB) in complex with acetoacetyl-CoA V Ulaganathan, MF Agacan, L Buetow, LB Tulloch, WN Hunter Acta Crystallographica Section F: Structural Biology and Crystallization …, 2007 | 29 | 2007 |
Norfloxacin salts of carboxylic acids curtail planktonic and biofilm mode of growth in ESKAPE pathogens RC Lowrence, A Ramakrishnan, NS Sundaramoorthy, A Shyam, V Mohan, ... Journal of applied microbiology 124 (2), 408-422, 2018 | 20 | 2018 |
Structure-activity relationship of pyrazolo pyrimidine derivatives as inhibitors of mitotic kinesin Eg5 and anticancer agents P Muthuraja, V Veeramani, S Prakash, M Himesh, ... Bioorganic Chemistry 84, 493-504, 2019 | 18 | 2019 |
Crystal engineering with heteroboranes. I. 1-Carboxy-1, 2-dicarba-closo-dodecaborane (11) AJ Welch, U Venkatasubramanian, GM Rosair, D Ellis, DJ Donohoe Acta Crystallographica Section C: Crystal Structure Communications 57 (11 …, 2001 | 16 | 2001 |
Identification of benzochromene derivatives as a highly specific NorA efflux pump inhibitor to mitigate the drug resistant strains of S. aureus A Ganesan, LR Christena, HMV Subbarao, U Venkatasubramanian, ... RSC advances 6 (36), 30258-30267, 2016 | 14 | 2016 |
Synthesis, molecular docking and ADME studies of thiazole-thiazolidinedione hybrids as antimicrobial agents SG Alegaon, V U, KR Alagawadi, D Kumar, RS Kavalapure, SD Ranade, ... Journal of Biomolecular Structure and Dynamics 40 (14), 6211-6227, 2022 | 12 | 2022 |
Disperse red 15 (DR15) impedes biofilm formation of uropathogenic Escherichia coli S Miryala, H Makala, SP Yadavali, U Venkatasubramanian, N Subbaiah, ... Microbial Pathogenesis 138, 103772, 2020 | 12 | 2020 |