| Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB DD Sarbassov, SM Ali, S Sengupta, JH Sheen, PP Hsu, AF Bagley, ... Molecular cell 22 (2), 159-168, 2006 | 3313 | 2006 |
| Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids Y Sancak, L Bar-Peled, R Zoncu, AL Markhard, S Nada, DM Sabatini Cell 141 (2), 290-303, 2010 | 2701 | 2010 |
| EMRE is an essential component of the mitochondrial calcium uniporter complex Y Sancak, AL Markhard, T Kitami, E Kovács-Bogdán, KJ Kamer, ... Science 342 (6164), 1379-1382, 2013 | 691 | 2013 |
| Architecture of the mitochondrial calcium uniporter K Oxenoid, Y Dong, C Cao, T Cui, Y Sancak, AL Markhard, Z Grabarek, ... Nature 533 (7602), 269-273, 2016 | 343 | 2016 |
| Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective … Q Liu, JW Chang, J Wang, SA Kang, CC Thoreen, A Markhard, W Hur, ... Journal of medicinal chemistry 53 (19), 7146-7155, 2010 | 286 | 2010 |
| Genetic screen for cell fitness in high or low oxygen highlights mitochondrial and lipid metabolism IH Jain, SE Calvo, AL Markhard, OS Skinner, TL To, T Ast, VK Mootha Cell 181 (3), 716-727. e11, 2020 | 166 | 2020 |
| Hepatic NADH reductive stress underlies common variation in metabolic traits RP Goodman, AL Markhard, H Shah, R Sharma, OS Skinner, CB Clish, ... Nature 583 (7814), 122-126, 2020 | 134 | 2020 |
| Development of ATP-competitive mTOR inhibitors Q Liu, SA Kang, CC Thoreen, W Hur, J Wang, JW Chang, A Markhard, ... mTOR: Methods and Protocols, 447-460, 2012 | 57 | 2012 |
| Congenital hypermetabolism and uncoupled oxidative phosphorylation RD Ganetzky, AL Markhard, I Yee, S Clever, A Cahill, H Shah, Z Grabarek, ... New England Journal of Medicine 387 (15), 1395-1403, 2022 | 16 | 2022 |
| Hypoxia extends lifespan and neurological function in a mouse model of aging RS Rogers, H Wang, TJ Durham, JA Stefely, NA Owiti, AL Markhard, ... PLoS biology 21 (5), e3002117, 2023 | 15 | 2023 |
| Reduced dosage of the chromosome axis factor Red1 selectively disrupts the meiotic recombination checkpoint in Saccharomyces cerevisiae TE Markowitz, D Suarez, HG Blitzblau, NJ Patel, AL Markhard, ... PLoS genetics 13 (7), e1006928, 2017 | 14 | 2017 |
| Evolutionary divergence reveals the molecular basis of EMRE dependence of the human MCU MJS MacEwen, AL Markhard, M Bozbeyoglu, F Bradford, O Goldberger, ... Life Science Alliance 3 (10), 2020 | 7 | 2020 |
| A genetically encoded system for oxygen generation in living cells AL Markhard, JG McCoy, TL To, VK Mootha Proceedings of the National Academy of Sciences 119 (43), e2207955119, 2022 | 6 | 2022 |
| ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits C Singh, B Jin, N Shrestha, AL Markhard, A Panda, SE Calvo, A Deik, ... Cell Metabolism 36 (1), 144-158. e7, 2024 | 4 | 2024 |
| PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity W Wei, X Lyu, AL Markhard, S Fu, RE Mardjuki, PE Cavanagh, X Zeng, ... Nature, 1-7, 2024 | | 2024 |
| A PTER-dependent pathway of taurine metabolism linked to energy balance W Wei, X Lyu, AL Markhard, S Fu, RE Mardjuki, PE Cavanagh, X Zeng, ... bioRxiv, 2024 | | 2024 |
