Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity S Chowdhry, Y Zhang, M McMahon, C Sutherland, A Cuadrado, ... Oncogene 32 (32), 3765-81;Epub 2012 Sep 10, 2013 | 658 | 2013 |
Involvement of the acid sphingomyelinase pathway in uva-induced apoptosis Y Zhang, P Mattjus, PC Schmid, Z Dong, S Zhong, WY Ma, RE Brown, ... Journal of Biological Chemistry 276 (15), 11775-11782, 2001 | 176 | 2001 |
Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum Y Zhang, DH Crouch, M Yamamoto, JD Hayes Biochemical Journal 399 (3), 373-385, 2006 | 144 | 2006 |
Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity Y Zhang, Y Xiang Biochemical Journal 473 (8), 961-1000, 2016 | 136 | 2016 |
Involvement of c‐jun NH2‐terminal kinases in resveratrol‐induced activation of p53 and apoptosis QB She, C Huang, Y Zhang, Z Dong Molecular Carcinogenesis: Published in cooperation with the University of …, 2002 | 135 | 2002 |
The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation Y Zhang, JM Lucocq, M Yamamoto, JD Hayes Biochemical Journal 408 (2), 161-172, 2007 | 123 | 2007 |
Signal transduction pathways involved in phosphorylation and activation of p70S6K following exposure to UVA irradiation Y Zhang, Z Dong, M Nomura, S Zhong, N Chen, AM Bode, Z Dong Journal of Biological Chemistry 276 (24), 20913-20923, 2001 | 121 | 2001 |
Nrf1 and Nrf2 transcription factors regulate androgen receptor transactivation in prostate cancer cells MA Schultz, SS Hagan, A Datta, Y Zhang, ML Freeman, SC Sikka, ... PloS one 9 (1), e87204, 2014 | 113* | 2014 |
Requirement of ATM in UVA-induced signaling and apoptosis Y Zhang, WY Ma, A Kaji, AM Bode, Z Dong Journal of Biological Chemistry 277 (5), 3124-3131, 2002 | 106 | 2002 |
UVA induces Ser381 phosphorylation of p90RSK/MAPKAP-K1 via ERK and JNK pathways Y Zhang, S Zhong, Z Dong, N Chen, AM Bode, W Ma, Z Dong Journal of Biological Chemistry 276 (18), 14572-14580, 2001 | 104 | 2001 |
MSK1 and JNKs mediate phosphorylation of STAT3 in UVA-irradiated mouse epidermal JB6 cells Y Zhang, G Liu, Z Dong Journal of Biological Chemistry 276 (45), 42534-42542, 2001 | 101 | 2001 |
mTORC1 signaling activates NRF1 to increase cellular proteasome levels Y Zhang, BD Manning Cell cycle 14 (13), 2011-2017, 2015 | 99 | 2015 |
Phosphorylation of 4E-BP1 is mediated by the p38/MSK1 pathway in response to UVB irradiation G Liu, Y Zhang, AM Bode, WY Ma, Z Dong Journal of Biological Chemistry 277 (11), 8810-8816, 2002 | 98 | 2002 |
The p53 protein is a novel substrate of ribosomal S6 kinase 2 and a critical intermediary for ribosomal S6 kinase 2 and histone H3 interaction YY Cho, Z He, Y Zhang, HS Choi, F Zhu, BY Choi, BS Kang, WY Ma, ... Cancer research 65 (9), 3596-3603, 2005 | 92 | 2005 |
The Nrf3 transcription factor is a membrane-bound glycoprotein targeted to the endoplasmic reticulum through its N-terminal homology box 1 sequence Y Zhang, A Kobayashi, M Yamamoto, JD Hayes Journal of Biological Chemistry 284 (5), 3195-3210, 2009 | 90 | 2009 |
The Nrf1 CNC/bZIP protein is a nuclear envelope-bound transcription factor that is activated by t-butyl hydroquinone but not by endoplasmic reticulum stressors Y Zhang, JM Lucocq, JD Hayes Biochemical Journal 418 (2), 293-310, 2009 | 81 | 2009 |
MAP kinases mediate UVB-induced phosphorylation of histone H3 at serine 28 S Zhong, Y Zhang, C Jansen, H Goto, M Inagaki, Z Dong Journal of Biological Chemistry 276 (16), 12932-12937, 2001 | 76 | 2001 |
Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domains Y Zhang, Y Ren, S Li, JD Hayes PloS one 9 (4), e93458, 2014 | 72 | 2014 |
Arsenite-induced phosphorylation of histone H3 at serine 10 is mediated by Akt1, extracellular signal-regulated kinase 2, and p90 ribosomal S6 kinase 2 but not mitogen-and … Z He, WY Ma, G Liu, Y Zhang, AM Bode, Z Dong Journal of Biological Chemistry 278 (12), 10588-10593, 2003 | 68 | 2003 |
Identification of topological determinants in the N-terminal domain of transcription factor Nrf1 that control its orientation in the endoplasmic reticulum membrane Y Zhang, JD Hayes Biochemical Journal 430 (3), 497-510, 2010 | 65 | 2010 |