Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega F Sievers, A Wilm, D Dineen, TJ Gibson, K Karplus, W Li, R Lopez, ... Molecular systems biology 7 (1), 539, 2011 | 15665 | 2011 |
Hidden Markov models for detecting remote protein homologies. K Karplus, C Barrett, R Hughey Bioinformatics (Oxford, England) 14 (10), 846-856, 1998 | 1483 | 1998 |
Improving physical realism, stereochemistry, and side‐chain accuracy in homology modeling: four approaches that performed well in CASP8 E Krieger, K Joo, J Lee, J Lee, S Raman, J Thompson, M Tyka, D Baker, ... Proteins: Structure, Function, and Bioinformatics 77 (S9), 114-122, 2009 | 1436 | 2009 |
Assignment of homology to genome sequences using a library of hidden Markov models that represent all proteins of known structure J Gough, K Karplus, R Hughey, C Chothia Journal of molecular biology 313 (4), 903-919, 2001 | 1433 | 2001 |
Automated forward and reverse ratcheting of DNA in a nanopore at 5-Å precision GM Cherf, KR Lieberman, H Rashid, CE Lam, K Karplus, M Akeson Nature biotechnology 30 (4), 344-348, 2012 | 705 | 2012 |
Sequence comparisons using multiple sequences detect three times as many remote homologues as pairwise methods J Park, K Karplus, C Barrett, R Hughey, D Haussler, T Hubbard, C Chothia Journal of Molecular Biology 284 (4), 1201-1210, 1998 | 696 | 1998 |
Digital synthesis of plucked-string and drum timbres K Karplus, A Strong Computer Music Journal 7 (2), 43-55, 1983 | 610 | 1983 |
Dirichlet mixtures: a method for improved detection of weak but significant protein sequence homology K Sjölander, K Karplus, M Brown, R Hughey, A Krogh, IS Mian, ... Bioinformatics 12 (4), 327-345, 1996 | 479 | 1996 |
A flexible motif search technique based on generalized profiles P Bucher, K Karplus, N Moeri, K Hofmann Computers & chemistry 20 (1), 3-23, 1996 | 391 | 1996 |
Classifying G-protein coupled receptors with support vector machines R Karchin, K Karplus, D Haussler Bioinformatics 18 (1), 147-159, 2002 | 373 | 2002 |
Combining local‐structure, fold‐recognition, and new fold methods for protein structure prediction K Karplus, R Karchin, J Draper, J Casper, Y Mandel‐Gutfreund, ... Proteins: Structure, Function, and Bioinformatics 53 (S6), 491-496, 2003 | 362 | 2003 |
Hidden Markov models that use predicted local structure for fold recognition: alphabets of backbone geometry R Karchin, M Cline, Y Mandel‐Gutfreund, K Karplus Proteins: Structure, Function, and Bioinformatics 51 (4), 504-514, 2003 | 255 | 2003 |
Predicting protein structure using hidden Markov models K Karplus, K Sjölander, C Barrett, M Cline, D Haussler, R Hughey, L Holm, ... Proteins: Structure, Function, and Bioinformatics 29 (S1), 134-139, 1997 | 229 | 1997 |
CAFASP‐1: Critical assessment of fully automated structure prediction methods D Fischer, C Barret, K Bryson, A Elofsson, A Godzik, D Jones, KJ Karplus, ... Proteins: Structure, Function, and Bioinformatics 37 (S3), 209-217, 1999 | 228 | 1999 |
Error rates for nanopore discrimination among cytosine, methylcytosine, and hydroxymethylcytosine along individual DNA strands J Schreiber, ZL Wescoe, R Abu-Shumays, JT Vivian, B Baatar, K Karplus, ... Proceedings of the National Academy of Sciences 110 (47), 18910-18915, 2013 | 206 | 2013 |
Predicting protein structure using only sequence information K Karplus, C Barrett, M Cline, M Diekhans, L Grate, R Hughey Proteins: Structure, Function, and Bioinformatics 37 (S3), 121-125, 1999 | 187 | 1999 |
SAM-T08, HMM-based protein structure prediction K Karplus Nucleic acids research 37 (suppl_2), W492-W497, 2009 | 179 | 2009 |
What is the value added by human intervention in protein structure prediction? K Karplus, R Karchin, C Barrett, S Tu, M Cline, M Diekhans, L Grate, ... Proteins: Structure, Function, and Bioinformatics 45 (S5), 86-91, 2001 | 178 | 2001 |
Identification and Characterization of RbmA, a Novel Protein Required for the Development of Rugose Colony Morphology and Biofilm Structure in Vibrio cholerae JCN Fong, K Karplus, GK Schoolnik, FH Yildiz Journal of bacteriology 188 (3), 1049-1059, 2006 | 175 | 2006 |
Xmap: A technology mapper for table-lookup field-programmable gate arrays K Karplus Proceedings of the 28th ACM/IEEE Design Automation Conference, 240-243, 1991 | 175 | 1991 |