关注
Mehtap Tugrak Sakarya, Assoc. Prof.Dr.
Mehtap Tugrak Sakarya, Assoc. Prof.Dr.
Faculty of Pharmacy,Tokat Gaziosmanpasa University, Department of pharmaceutical chemistry
在 gop.edu.tr 的电子邮件经过验证
标题
引用次数
引用次数
年份
Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides
HI Gul, M Tugrak, H Sakagami, P Taslimi, I Gulcin, CT Supuran
Journal of Enzyme Inhibition and Medicinal Chemistry 31 (6), 1619-1624, 2016
1242016
Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors
M Tugrak, HI Gul, K Bandow, H Sakagami, I Gulcin, Y Ozkay, CT Supuran
Bioorganic Chemistry 90, 103095, 2019
632019
New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno [1, 2-b] pyridin-5-ones
M Tugrak, HI Gul, H Sakagami, I Gulcin, CT Supuran
Bioorganic chemistry 81, 433-439, 2018
622018
Synthesis of mono Mannich bases of 2-(4-hydroxybenzylidene)-2, 3-dihydroinden-1-one and evaluation of their cytotoxicities
M Tugrak, C Yamali, H Sakagami, HI Gul
Journal of Enzyme Inhibition and Medicinal Chemistry 31 (5), 818-823, 2016
592016
New phenolic Mannich bases with piperazines and their bioactivities
HI Gul, M Tugrak, M Gul, S Mazlumoglu, H Sakagami, I Gulcin, ...
Bioorganic chemistry 90, 103057, 2019
532019
The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes
C Yamali, M Tugrak, HI Gul, M Tanc, CT Supuran
Journal of enzyme inhibition and medicinal chemistry 31 (6), 1678-1681, 2016
472016
Synthesis and in vitro carbonic anhydrases and acetylcholinesterase inhibitory activities of novel imidazolinone‐based benzenesulfonamides
M Tugrak, HI Gul, Y Demir, S Levent, I Gulcin
Archiv der Pharmazie 354 (4), 2000375, 2021
432021
Synthesis of benzamide derivatives with thiourea‐substituted benzenesulfonamides as carbonic anhydrase inhibitors
M Tugrak, HI Gul, Y Demir, I Gulcin
Archiv der Pharmazie 354 (2), 2000230, 2021
272021
Synthesis and anticancer properties of mono Mannich bases containing vanillin moiety
M Tugrak, HI Gul, H Sakagami, E Mete
Medicinal Chemistry Research 26, 1528-1534, 2017
262017
Phenothiazine‐based chalcones as potential dual‐target inhibitors toward cholinesterases (AChE, BuChE) and monoamine oxidases (MAO‐A, MAO‐B)
C Yamali, FS Engin, S Bilginer, M Tugrak, D Ozmen Ozgun, G Ozli, ...
Journal of Heterocyclic Chemistry 58 (1), 161-171, 2021
212021
Synthesis of some acrylophenones with N-methylpiperazine and evaluation of their cytotoxicities
HI Gul, M Tugrak, H Sakagami
Journal of Enzyme Inhibition and Medicinal Chemistry 31 (1), 147-151, 2016
192016
Synthesis and cytotoxicities of 2-[4-hydroxy-(3, 5-bis-aminomethyl)-benzylidene]-indan-1-ones
M Tugrak, H Inci Gul, H Sakagami
Letters in Drug Design & Discovery 12 (10), 806-812, 2015
182015
Quinazolinone-based benzenesulfonamides with low toxicity and high affinity as monoamine oxidase-A inhibitors: Synthesis, biological evaluation and induced-fit docking studies
C Yamali, HI Gul, MT Sakarya, BN Saglik, A Ece, G Demirel, M Nenni, ...
Bioorganic Chemistry 124, 105822, 2022
172022
Investigation of solvent effect on photophysical properties of some sulfonamides derivatives 2
E BOZKURT, Hİ GÜL, M TUĞRAK
172017
Synthesis, cytotoxic, and carbonic anhydrase inhibitory effects of new 2‐(3‐(4‐methoxyphenyl)‐5‐(aryl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl)benzo[d]thiazole derivatives
M Tugrak, HI Gul, H Sakagami, I Gulcin
Journal of Heterocyclic Chemistry 57 (7), 2762-2768, 2020
142020
Synthesis and cytotoxicities of new azafluorenones with apoptotic mechanism of action and cell cycle analysis
HI Gul, M Tugrak, M Gul, H Sakagami, N Umemura, B Anil
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018
132018
Synthesis and pharmacological effects of novel benzenesulfonamides carryingbenzamide moiety as carbonic anhydrase and acetylcholinesterase inhibitors
M Tuğrak, Hİ GÜl, B ANIL, İ GÜlÇİn
Turkish Journal of Chemistry 44 (6), 1601-1609, 2020
122020
Acetylcholinesterase inhibitory potencies of new pyrazoline derivatives
M TUĞRAK, Hİ GÜL, İ GÜLÇİN
Journal of Research in Pharmacy 24 (4), 464-471, 2020
102020
New chalcone derivatives with pyrazole and sulfonamide pharmacophores as carbonic anhydrase inhibitors
M Tugrak, HI Gul, H Akincioglu, I Gulcin
Letters in Drug Design & Discovery 18 (2), 191-198, 2021
82021
Synthesis and biological evaluation of new pyrazolebenzene-sulphonamides as potentialanticancer agents and hCA I and II inhibitors
M Tuğrak, Hİ Gül, H Sakagami, R Kaya, İ Gülçin
Turkish Journal of Chemistry 45 (3), 528-539, 2021
72021
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