Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides HI Gul, M Tugrak, H Sakagami, P Taslimi, I Gulcin, CT Supuran Journal of Enzyme Inhibition and Medicinal Chemistry 31 (6), 1619-1624, 2016 | 124 | 2016 |
Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors M Tugrak, HI Gul, K Bandow, H Sakagami, I Gulcin, Y Ozkay, CT Supuran Bioorganic Chemistry 90, 103095, 2019 | 63 | 2019 |
New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno [1, 2-b] pyridin-5-ones M Tugrak, HI Gul, H Sakagami, I Gulcin, CT Supuran Bioorganic chemistry 81, 433-439, 2018 | 62 | 2018 |
Synthesis of mono Mannich bases of 2-(4-hydroxybenzylidene)-2, 3-dihydroinden-1-one and evaluation of their cytotoxicities M Tugrak, C Yamali, H Sakagami, HI Gul Journal of Enzyme Inhibition and Medicinal Chemistry 31 (5), 818-823, 2016 | 59 | 2016 |
New phenolic Mannich bases with piperazines and their bioactivities HI Gul, M Tugrak, M Gul, S Mazlumoglu, H Sakagami, I Gulcin, ... Bioorganic chemistry 90, 103057, 2019 | 53 | 2019 |
The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes C Yamali, M Tugrak, HI Gul, M Tanc, CT Supuran Journal of enzyme inhibition and medicinal chemistry 31 (6), 1678-1681, 2016 | 47 | 2016 |
Synthesis and in vitro carbonic anhydrases and acetylcholinesterase inhibitory activities of novel imidazolinone‐based benzenesulfonamides M Tugrak, HI Gul, Y Demir, S Levent, I Gulcin Archiv der Pharmazie 354 (4), 2000375, 2021 | 43 | 2021 |
Synthesis of benzamide derivatives with thiourea‐substituted benzenesulfonamides as carbonic anhydrase inhibitors M Tugrak, HI Gul, Y Demir, I Gulcin Archiv der Pharmazie 354 (2), 2000230, 2021 | 27 | 2021 |
Synthesis and anticancer properties of mono Mannich bases containing vanillin moiety M Tugrak, HI Gul, H Sakagami, E Mete Medicinal Chemistry Research 26, 1528-1534, 2017 | 26 | 2017 |
Phenothiazine‐based chalcones as potential dual‐target inhibitors toward cholinesterases (AChE, BuChE) and monoamine oxidases (MAO‐A, MAO‐B) C Yamali, FS Engin, S Bilginer, M Tugrak, D Ozmen Ozgun, G Ozli, ... Journal of Heterocyclic Chemistry 58 (1), 161-171, 2021 | 21 | 2021 |
Synthesis of some acrylophenones with N-methylpiperazine and evaluation of their cytotoxicities HI Gul, M Tugrak, H Sakagami Journal of Enzyme Inhibition and Medicinal Chemistry 31 (1), 147-151, 2016 | 19 | 2016 |
Synthesis and cytotoxicities of 2-[4-hydroxy-(3, 5-bis-aminomethyl)-benzylidene]-indan-1-ones M Tugrak, H Inci Gul, H Sakagami Letters in Drug Design & Discovery 12 (10), 806-812, 2015 | 18 | 2015 |
Quinazolinone-based benzenesulfonamides with low toxicity and high affinity as monoamine oxidase-A inhibitors: Synthesis, biological evaluation and induced-fit docking studies C Yamali, HI Gul, MT Sakarya, BN Saglik, A Ece, G Demirel, M Nenni, ... Bioorganic Chemistry 124, 105822, 2022 | 17 | 2022 |
Investigation of solvent effect on photophysical properties of some sulfonamides derivatives 2 E BOZKURT, Hİ GÜL, M TUĞRAK | 17 | 2017 |
Synthesis, cytotoxic, and carbonic anhydrase inhibitory effects of new 2‐(3‐(4‐methoxyphenyl)‐5‐(aryl)‐4,5‐dihydro‐1H‐pyrazol‐1‐yl)benzo[d]thiazole derivatives M Tugrak, HI Gul, H Sakagami, I Gulcin Journal of Heterocyclic Chemistry 57 (7), 2762-2768, 2020 | 14 | 2020 |
Synthesis and cytotoxicities of new azafluorenones with apoptotic mechanism of action and cell cycle analysis HI Gul, M Tugrak, M Gul, H Sakagami, N Umemura, B Anil Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018 | 13 | 2018 |
Synthesis and pharmacological effects of novel benzenesulfonamides carryingbenzamide moiety as carbonic anhydrase and acetylcholinesterase inhibitors M Tuğrak, Hİ GÜl, B ANIL, İ GÜlÇİn Turkish Journal of Chemistry 44 (6), 1601-1609, 2020 | 12 | 2020 |
Acetylcholinesterase inhibitory potencies of new pyrazoline derivatives M TUĞRAK, Hİ GÜL, İ GÜLÇİN Journal of Research in Pharmacy 24 (4), 464-471, 2020 | 10 | 2020 |
New chalcone derivatives with pyrazole and sulfonamide pharmacophores as carbonic anhydrase inhibitors M Tugrak, HI Gul, H Akincioglu, I Gulcin Letters in Drug Design & Discovery 18 (2), 191-198, 2021 | 8 | 2021 |
Synthesis and biological evaluation of new pyrazolebenzene-sulphonamides as potentialanticancer agents and hCA I and II inhibitors M Tuğrak, Hİ Gül, H Sakagami, R Kaya, İ Gülçin Turkish Journal of Chemistry 45 (3), 528-539, 2021 | 7 | 2021 |