Genome-wide DNA methylation events in TMPRSS2–ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation ST Börno, A Fischer, M Kerick, M Fälth, M Laible, JC Brase, R Kuner, ... Cancer discovery 2 (11), 1024-1035, 2012 | 159 | 2012 |
Homemade site directed mutagenesis of whole plasmids M Laible, K Boonrod Journal of visualized experiments: JoVE, 2009 | 124 | 2009 |
Comparison of immunohistochemistry with PCR for assessment of ER, PR, and Ki-67 and prediction of pathological complete response in breast cancer HP Sinn, A Schneeweiss, M Keller, K Schlombs, M Laible, J Seitz, S Lakis, ... BMC cancer 17, 1-10, 2017 | 98 | 2017 |
Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and … M Laible, K Schlombs, K Kaiser, E Veltrup, S Herlein, S Lakis, R Stöhr, ... BMC cancer 16, 1-14, 2016 | 57 | 2016 |
Biological subtyping of early breast cancer: a study comparing RT-qPCR with immunohistochemistry RM Wirtz, H Sihto, J Isola, P Heikkilä, PL Kellokumpu-Lehtinen, P Auvinen, ... Breast cancer research and treatment 157, 437-446, 2016 | 50 | 2016 |
An international reproducibility study validating quantitative determination of ERBB2, ESR1, PGR, and MKI67 mRNA in breast cancer using MammaTyper® Z Varga, A Lebeau, H Bu, A Hartmann, F Penault-Llorca, E Guerini-Rocco, ... Breast Cancer Research 19, 1-13, 2017 | 45 | 2017 |
TMPRSS2: ERG gene fusion variants induce TGF-β signaling and epithelial to mesenchymal transition in human prostate cancer cells L Ratz, M Laible, LA Kacprzyk, SM Wittig-Blaich, Y Tolstov, S Duensing, ... Oncotarget 8 (15), 25115, 2017 | 35 | 2017 |
ERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer LA Kacprzyk, M Laible, T Andrasiuk, JC Brase, ST Börno, M Fälth, ... PLoS One 8 (3), e59976, 2013 | 33 | 2013 |
ERBB2 expression as potential risk-stratification for early cystectomy in patients with pT1 bladder cancer and concomitant carcinoma in situ J Breyer, W Otto, RM Wirtz, B Wullich, B Keck, P Erben, MC Kriegmair, ... Urologia Internationalis 98 (3), 282-289, 2017 | 32 | 2017 |
ESR1, ERBB2, and Ki67 mRNA expression predicts stage and grade of non-muscle-invasive bladder carcinoma (NMIBC) J Breyer, RM Wirtz, M Laible, K Schlombs, P Erben, MC Kriegmair, ... Virchows Archiv 469, 547-552, 2016 | 32 | 2016 |
Predictive value of molecular subtyping in NMIBC by RT-qPCR of ERBB2, ESR1, PGR and MKI67 from formalin fixed TUR biopsies J Breyer, RM Wirtz, W Otto, M Laible, K Schlombs, P Erben, MC Kriegmair, ... Oncotarget 8 (40), 67684, 2017 | 20 | 2017 |
Impact of molecular subtypes on the prediction of distant recurrence in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) negative breast cancer … M Laible, K Hartmann, C Gürtler, T Anzeneder, R Wirtz, S Weber, T Keller, ... BMC cancer 19, 1-9, 2019 | 15 | 2019 |
Contact spotting of protein microarrays coupled with spike‐in of normalizer protein permits time‐resolved analysis of ERBB receptor signaling C Löbke, M Laible, C Rappl, M Ruschhaupt, Ö Sahin, D Arlt, S Wiemann, ... Proteomics 8 (8), 1586-1594, 2008 | 15 | 2008 |
Looking for more reliable biomarkers in breast cancer: Comparison between routine methods and RT-qPCR E Caselli, C Pelliccia, V Teti, G Bellezza, M Mandarano, I Ferri, ... PLoS One 16 (9), e0255580, 2021 | 9 | 2021 |
Transferring a quantitative molecular diagnostic test to multiple real-time quantitative PCR platforms C Gürtler, M Laible, W Schwabe, H Steinhäuser, X Li, S Liu, K Schlombs, ... The Journal of Molecular Diagnostics 20 (4), 398-414, 2018 | 9 | 2018 |
The tight junction protein claudin 6 is a potential target for patient-individualized treatment in esophageal and gastric adenocarcinoma and is associated with poor prognosis AG Simon, SI Lyu, M Laible, S Wöll, Ö Türeci, U Şahin, H Alakus, L Fahrig, ... Journal of Translational Medicine 21 (1), 552, 2023 | 6 | 2023 |
Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissue K Hartmann, K Schlombs, M Laible, C Gürtler, M Schmidt, U Sahin, ... Diagnostic pathology 13, 1-10, 2018 | 3 | 2018 |
Validation of the MammaTyper® pathological complete response (pCR)-score as a predictor for response after neoadjuvant chemotherapy (NACT) in patients with early breast cancer (BC) PA Fasching, M Laible, KE Weber, RM Wirtz, C Denkert, K Schlombs, ... Annals of Oncology 29, viii53, 2018 | 1 | 2018 |
Evaluation of the MammaTyper® as a molecular predictor for pathological complete response (pCR) after neoadjuvant chemotherapy (NACT) and outcome in patients with different … PA Fasching, M Laible, KE Weber, RM Wirtz, C Denkert, K Schlombs, ... Annals of Oncology 29, viii73, 2018 | 1 | 2018 |
Overexpression of TMPRSS2: ERG variants activates TGF-β signaling and promotes invasion of prostate cancer cells L Ratz, M Laible, P Altevogt, SM Klauck, H Sültmann European Journal of Cancer 1 (61), S14, 2016 | 1 | 2016 |