Prior exposure to salient win-paired cues in a rat gambling task increases sensitivity to cocaine self-administration and suppresses dopamine efflux in nucleus accumbens … JMN Ferland, TJ Hynes, CD Hounjet, D Lindenbach, CV Haar, WK Adams, ... Journal of Neuroscience 39 (10), 1842-1854, 2019 | 38 | 2019 |
Early life adversity potentiates expression of addiction-related traits TJ Hynes, CS Thomas, AS Zumbusch, A Samson, I Petriman, U Mrdja, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 87, 56-67, 2018 | 30 | 2018 |
Dopamine neurons gate the intersection of cocaine use, decision making, and impulsivity TJ Hynes, KM Hrelja, BA Hathaway, CD Hounjet, CS Chernoff, SA Ebsary, ... Addiction Biology 26 (6), e13022, 2021 | 24 | 2021 |
Noradrenergic contributions to cue-driven risk-taking and impulsivity CS Chernoff, TJ Hynes, CA Winstanley Psychopharmacology 238, 1765-1779, 2021 | 22 | 2021 |
Chemogenetic inhibition of dopaminergic projections to the nucleus accumbens has sexually dimorphic effects in the rat gambling task. TJ Hynes, JMM Ferland, TL Feng, WK Adams, MM Silveira, M Tremblay, ... Behavioral Neuroscience 134 (4), 309, 2020 | 20 | 2020 |
Pharmacological evidence of a cholinergic contribution to elevated impulsivity and risky decision-making caused by adding win-paired cues to a rat gambling task GD Betts, TJ Hynes, CA Winstanley Journal of Psychopharmacology 35 (6), 701-712, 2021 | 17 | 2021 |
D2/3 agonist during learning potentiates cued risky choice L Mortazavi, TJ Hynes, CS Chernoff, S Ramaiah, HG Brodie, B Russell, ... Journal of Neuroscience 43 (6), 979-992, 2023 | 8 | 2023 |
Clueless about cues: the impact of reward-paired cues on decision making under uncertainty CA Winstanley, TJ Hynes Current Opinion in Behavioral Sciences 41, 167-174, 2021 | 7 | 2021 |
GPR52 agonists attenuate ropinirole-induced preference for uncertain outcomes. B Russell, MM Barrus, M Tremblay, L Ma, K Hrelja, C Wong, TJ Hynes, ... Behavioral neuroscience 135 (1), 8, 2021 | 5 | 2021 |
Win-paired cues modulate the effect of dopamine neuron sensitization on decision making and cocaine self-administration: divergent effects across sex TJ Hynes, CS Chernoff, KM Hrelja, TL Maric, DK Avramidis, ... Biological Psychiatry 95 (3), 220-230, 2024 | 4 | 2024 |
Biological sex influences the contribution of sign-tracking and anxiety-like behavior toward remifentanil self-administration. A Zumbusch, A Samson, C Chernoff, B Coslovich, T Hynes Behavioral Neuroscience 137 (3), 196, 2023 | 3 | 2023 |
Noradrenergic regulation of cue-guided decision making and impulsivity is doubly dissociable across frontal brain regions CS Chernoff, TJ Hynes, JD Schumacher, S Ramaiah, DK Avramidis, ... Psychopharmacology 241 (4), 767-783, 2024 | 2 | 2024 |
Pan‐striatal reduction in the expression of the astrocytic dopamine transporter precedes the development of dorsolateral striatum dopamine‐dependent incentive heroin seeking habits T Hynes, M Fouyssac, M Puaud, D Joshi, C Chernoff, S Stiebahl, ... European Journal of Neuroscience 59 (10), 2502-2521, 2024 | 1 | 2024 |
Chemogenetic inhibition of ventral tegmental dopamine neurons prevents cocaine-induced deficits in decision making in both sexes TJ Hynes, BA Hathaway, KM Hrelja, SA Ebsary, CS Chernoff, L Ma, ... Pharmacological Reports 71 (6), 1310, 2019 | 1 | 2019 |
Audiovisual cues must be predictable and win-paired to drive risky choice BA Hathaway, DR Kim, SBA Malhas, KM Hrelja, L Kerker, TJ Hynes, ... bioRxiv, 2022.09. 20.507379, 2022 | | 2022 |
Probing the role of dopamine at the intersection of addiction, decision making, and sex T Hynes University of British Columbia, 2021 | | 2021 |
Contributions of early life adversity, sex, and traits towards compulsive opioid self-administration T Hynes | | 2017 |