Molecular mechanisms of TDP-43 misfolding and pathology in amyotrophic lateral sclerosis A Prasad, V Bharathi, V Sivalingam, A Girdhar, BK Patel Frontiers in molecular neuroscience 12, 25, 2019 | 638 | 2019 |
Use of ade1 and ade2 mutations for development of a versatile red/white colour assay of amyloid‐induced oxidative stress in saccharomyces cerevisiae V Bharathi, A Girdhar, A Prasad, M Verma, V Taneja, BK Patel Yeast 33 (12), 607-620, 2016 | 37 | 2016 |
The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization A Prasad, V Sivalingam, V Bharathi, A Girdhar, BK Patel Biochimie 150, 76-87, 2018 | 35 | 2018 |
Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase … A Girdhar, V Bharathi, VR Tiwari, S Abhishek, W Deeksha, US Mahawar, ... International journal of biological macromolecules 147, 117-130, 2020 | 31 | 2020 |
Amyloid-like aggregation of bovine serum albumin at physiological temperature induced by cross-seeding effect of HEWL amyloid aggregates S Nirwal, V Bharathi, BK Patel Biophysical Chemistry 278, 106678, 2021 | 22 | 2021 |
Role of CNC1 gene in TDP-43 aggregation-induced oxidative stress-mediated cell death in S. cerevisiae model of ALS V Bharathi, A Girdhar, BK Patel Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (6), 118993, 2021 | 14 | 2021 |
Molecular mechanisms of TDP-43 misfolding and pathology in amyotrophic lateral sclerosis. Front Mol Neurosci. 2019; 12: 25 A Prasad, V Bharathi, V Sivalingam, A Girdhar, BK Patel Epub 2019/03/07. doi: 10.3389/fnmol. 2019.00025. PubMed PMID: 30837838, 2019 | 11 | 2019 |
Zn2+ modulates in vitro phase separation of TDP-432C and mutant TDP-432C-A315T C-terminal fragments of TDP-43 protein implicated in ALS and FTLD-TDP diseases S Preethi, V Bharathi, BK Patel International journal of biological macromolecules 176, 186-200, 2021 | 9 | 2021 |
A protocol of using white/red color assay to measure amyloid-induced oxidative stress in Saccharomyces cerevisiae V Bharathi, A Girdhar, BK Patel Bio-protocol 7 (15), e2440-e2440, 2017 | 9 | 2017 |
Elevated constitutive expression of Hsp40 chaperone Sis1 reduces TDP-43 aggregation-induced oxidative stress in Ire1 pathway dependent-manner in yeast TDP-43 proteinopathy … V Bharathi, A Bajpai, IT Parappuram, BK Patel Biochemical and Biophysical Research Communications 595, 28-34, 2022 | 7 | 2022 |
BK Patel Molecular mechanisms of TDP-43 misfolding and pathology in amyotrophic lateral sclerosis., 2019, 12 A Prasad, V Bharathi, V Sivalingam, A Girdhar DOI: https://doi. org/10.3389/fnmol, 25, 2019 | 7 | 2019 |
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia JD Marks, VE Ayuso, Y Carlomagno, M Yue, TW Todd, Y Hao, Z Li, ... Science translational medicine 16 (730), eadf9735, 2024 | 6 | 2024 |
TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes Y Zeng, A Lovchykova, T Akiyama, C Liu, C Guo, VM Jawahar, O Sianto, ... BioRxiv, 2024 | 5 | 2024 |
TDP-43 proteinopathy mechanisms from non-mammalian model systems V Bharathi, A Girdhar, BK Patel TDP-43 and Neurodegeneration, 153-181, 2022 | 2 | 2022 |
Pharmaceutical acetylation can modulate the amyloidogenicity of human serum albumin V Bharathi, RR Manglunia, N Sharma, S Nirwal, BK Patel Indian Journal of Biochemistry and Biophysics (IJBB) 58 (4), 344-351, 2021 | 2 | 2021 |