Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation D Klysz, X Tai, PA Robert, M Craveiro, G Cretenet, L Oburoglu, ... Science signaling 8 (396), ra97-ra97, 2015 | 480 | 2015 |
Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification L Oburoglu, S Tardito, V Fritz, SC De Barros, P Merida, M Craveiro, ... Cell stem cell 15 (2), 169-184, 2014 | 302 | 2014 |
Glut1-mediated glucose transport regulates HIV infection S Loisel-Meyer, L Swainson, M Craveiro, L Oburoglu, C Mongellaz, ... Proceedings of the National Academy of Sciences 109 (7), 2549-2554, 2012 | 150 | 2012 |
Cell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions G Cretenet, I Clerc, M Matias, S Loisel, M Craveiro, L Oburoglu, S Kinet, ... Scientific reports 6 (1), 24129, 2016 | 106 | 2016 |
Metabolic regulation of hematopoietic stem cell commitment and erythroid differentiation L Oburoglu, M Romano, N Taylor, S Kinet Current Opinion in Hematology 23 (3), 198-205, 2016 | 90 | 2016 |
Entry of glucose-and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells I Clerc, D Abba Moussa, Z Vahlas, S Tardito, L Oburoglu, TJ Hope, ... Nature metabolism 1 (7), 717-730, 2019 | 82 | 2019 |
Hematopoietic stem cell lineage specification M Pouzolles, L Oburoglu, N Taylor, VS Zimmermann Current opinion in hematology 23 (4), 311-317, 2016 | 42 | 2016 |
An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism P Gonzalez-Menendez, M Romano, H Yan, R Deshmukh, J Papoin, ... Cell reports 34 (5), 2021 | 38 | 2021 |
S100A6 is a critical regulator of hematopoietic stem cells THM Grahn, A Niroula, Á Végvári, L Oburoglu, M Pertesi, S Warsi, F Safi, ... Leukemia 34 (12), 3323-3337, 2020 | 22 | 2020 |
Site-specific CRISPR-based mitochondrial DNA manipulation is limited by gRNA import L Schmiderer, D Yudovich, L Oburoglu, M Hjort, J Larsson Scientific Reports 12 (1), 18687, 2022 | 18 | 2022 |
Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence L Oburoglu, E Mansell, I Canals, V Sigurdsson, C Guibentif, S Soneji, ... EMBO reports 23 (2), e54384, 2022 | 14 | 2022 |
Glutamine metabolism regulates endothelial to hematopoietic transition and hematopoietic lineage specification L Oburoglu, E Mansell, NB Woods Scientific Reports 11 (1), 17589, 2021 | 13 | 2021 |
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity M Rodriguez-Zabala, R Ramakrishnan, K Reinbach, S Ghosh, L Oburoglu, ... Blood Advances 7 (18), 5382-5395, 2023 | 9 | 2023 |
FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis A Monsalve, I Canals, L Oburoglu Frontiers in cell and developmental biology 10, 1039636, 2022 | 5 | 2022 |
Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia I Canals, A Comella-Bolla, E Cepeda-Prado, N Avaliani, JA Crowe, ... Brain communications 5 (3), fcad158, 2023 | 4 | 2023 |
Ciclopirox ethanolamine preserves the immature state of human HSCs by mediating intracellular iron content MS Talkhoncheh, A Baudet, F Ek, A Subramaniam, YR Kao, N Miharada, ... Blood Advances 7 (24), 7407-7417, 2023 | 1 | 2023 |
Hematopoietic cells emerging from hemogenic endothelium exhibit lineage-specific oxidative stress responses H Biezeman, M Nubiè, L Oburoglu Journal of Biological Chemistry, 107815, 2024 | | 2024 |
BRAIN COMMUNICATIONS I Canals, A Comella-Bolla, E Cepeda-Prado, N Avaliani, JA Crowe, ... | | 2023 |
Metabolism guides definitive lineage specification during endothelial to hematopoietic transition NB Woods, L Oburoglu US Patent App. 17/756,618, 2022 | | 2022 |
In Vivo crispr Screening Identifies GLUT1 As a Key Metabolic Regulator of MLL-AF9-Driven Acute Myeloid Leukemia MR Zabala, R Ramakrishnan, K Reinbach, L Oburoglu, S Ghosh, ... Blood 138, 3439, 2021 | | 2021 |