关注
Leal Oburoglu
Leal Oburoglu
Institute for Regenerative Medicine, University of Zurich
在 irem.uzh.ch 的电子邮件经过验证
标题
引用次数
引用次数
年份
Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation
D Klysz, X Tai, PA Robert, M Craveiro, G Cretenet, L Oburoglu, ...
Science signaling 8 (396), ra97-ra97, 2015
4802015
Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification
L Oburoglu, S Tardito, V Fritz, SC De Barros, P Merida, M Craveiro, ...
Cell stem cell 15 (2), 169-184, 2014
3022014
Glut1-mediated glucose transport regulates HIV infection
S Loisel-Meyer, L Swainson, M Craveiro, L Oburoglu, C Mongellaz, ...
Proceedings of the National Academy of Sciences 109 (7), 2549-2554, 2012
1502012
Cell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions
G Cretenet, I Clerc, M Matias, S Loisel, M Craveiro, L Oburoglu, S Kinet, ...
Scientific reports 6 (1), 24129, 2016
1062016
Metabolic regulation of hematopoietic stem cell commitment and erythroid differentiation
L Oburoglu, M Romano, N Taylor, S Kinet
Current Opinion in Hematology 23 (3), 198-205, 2016
902016
Entry of glucose-and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells
I Clerc, D Abba Moussa, Z Vahlas, S Tardito, L Oburoglu, TJ Hope, ...
Nature metabolism 1 (7), 717-730, 2019
822019
Hematopoietic stem cell lineage specification
M Pouzolles, L Oburoglu, N Taylor, VS Zimmermann
Current opinion in hematology 23 (4), 311-317, 2016
422016
An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism
P Gonzalez-Menendez, M Romano, H Yan, R Deshmukh, J Papoin, ...
Cell reports 34 (5), 2021
382021
S100A6 is a critical regulator of hematopoietic stem cells
THM Grahn, A Niroula, Á Végvári, L Oburoglu, M Pertesi, S Warsi, F Safi, ...
Leukemia 34 (12), 3323-3337, 2020
222020
Site-specific CRISPR-based mitochondrial DNA manipulation is limited by gRNA import
L Schmiderer, D Yudovich, L Oburoglu, M Hjort, J Larsson
Scientific Reports 12 (1), 18687, 2022
182022
Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence
L Oburoglu, E Mansell, I Canals, V Sigurdsson, C Guibentif, S Soneji, ...
EMBO reports 23 (2), e54384, 2022
142022
Glutamine metabolism regulates endothelial to hematopoietic transition and hematopoietic lineage specification
L Oburoglu, E Mansell, NB Woods
Scientific Reports 11 (1), 17589, 2021
132021
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
M Rodriguez-Zabala, R Ramakrishnan, K Reinbach, S Ghosh, L Oburoglu, ...
Blood Advances 7 (18), 5382-5395, 2023
92023
FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis
A Monsalve, I Canals, L Oburoglu
Frontiers in cell and developmental biology 10, 1039636, 2022
52022
Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia
I Canals, A Comella-Bolla, E Cepeda-Prado, N Avaliani, JA Crowe, ...
Brain communications 5 (3), fcad158, 2023
42023
Ciclopirox ethanolamine preserves the immature state of human HSCs by mediating intracellular iron content
MS Talkhoncheh, A Baudet, F Ek, A Subramaniam, YR Kao, N Miharada, ...
Blood Advances 7 (24), 7407-7417, 2023
12023
Hematopoietic cells emerging from hemogenic endothelium exhibit lineage-specific oxidative stress responses
H Biezeman, M Nubiè, L Oburoglu
Journal of Biological Chemistry, 107815, 2024
2024
BRAIN COMMUNICATIONS
I Canals, A Comella-Bolla, E Cepeda-Prado, N Avaliani, JA Crowe, ...
2023
Metabolism guides definitive lineage specification during endothelial to hematopoietic transition
NB Woods, L Oburoglu
US Patent App. 17/756,618, 2022
2022
In Vivo crispr Screening Identifies GLUT1 As a Key Metabolic Regulator of MLL-AF9-Driven Acute Myeloid Leukemia
MR Zabala, R Ramakrishnan, K Reinbach, L Oburoglu, S Ghosh, ...
Blood 138, 3439, 2021
2021
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