Targeted drug delivery strategies for precision medicines MT Manzari, Y Shamay, H Kiguchi, N Rosen, M Scaltriti, DA Heller Nature Reviews Materials 6 (4), 351-370, 2021 | 534 | 2021 |
P-selectin is a nanotherapeutic delivery target in the tumor microenvironment Y Shamay, M Elkabets, H Li, J Shah, S Brook, F Wang, K Adler, E Baut, ... Science translational medicine 8 (345), 345ra87-345ra87, 2016 | 186 | 2016 |
Quantitative self-assembly prediction yields targeted nanomedicines Y Shamay, J Shah, M Işık, A Mizrachi, J Leibold, DF Tschaharganeh, ... Nature materials 17 (4), 361-368, 2018 | 163 | 2018 |
Light induced drug delivery into cancer cells Y Shamay, L Adar, G Ashkenasy, A David Biomaterials 32 (5), 1377-1386, 2011 | 150 | 2011 |
Tumour-specific PI3K inhibition via nanoparticle-targeted delivery in head and neck squamous cell carcinoma A Mizrachi, Y Shamay, J Shah, S Brook, J Soong, VK Rajasekhar, ... Nature communications 8 (1), 14292, 2017 | 107 | 2017 |
Cell Membrane Proteins Modulate the Carbon Nanotube Optical Bandgap via Surface Charge Accumulation D Roxbury, PV Jena, Y Shamay, CP Horoszko, DA Heller ACS nano 10 (1), 499-506, 2016 | 79 | 2016 |
Hyaluronan oligomers-HPMA copolymer conjugates for targeting paclitaxel to CD44-overexpressing ovarian carcinoma G Journo-Gershfeld, D Kapp, Y Shamay, J Kopeček, A David Pharmaceutical research 29, 1121-1133, 2012 | 72 | 2012 |
E-selectin binding peptide–polymer–drug conjugates and their selective cytotoxicity against vascular endothelial cells Y Shamay, D Paulin, G Ashkenasy, A David Biomaterials 30 (32), 6460-6468, 2009 | 69 | 2009 |
P-selectin-targeted nanocarriers induce active crossing of the blood–brain barrier via caveolin-1-dependent transcytosis DE Tylawsky, H Kiguchi, J Vaynshteyn, J Gerwin, J Shah, T Islam, ... Nature materials 22 (3), 391-399, 2023 | 59 | 2023 |
Photoluminescent carbon nanotubes interrogate the permeability of multicellular tumor spheroids PV Jena, Y Shamay, J Shah, D Roxbury, N Paknejad, DA Heller Carbon 97, 99-109, 2016 | 54 | 2016 |
Inhibition of primary and metastatic tumors in mice by E-selectin-targeted polymer–drug conjugates Y Shamay, L Raviv, M Golan, E Voronov, RN Apte, A David Journal of Controlled Release 217, 102-112, 2015 | 45 | 2015 |
Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer E Kopansky, Y Shamay, A David Journal of Drug Targeting 19 (10), 933-943, 2011 | 44 | 2011 |
Merging data curation and machine learning to improve nanomedicines C Chen, Z Yaari, E Apfelbaum, P Grodzinski, Y Shamay, DA Heller Advanced drug delivery reviews 183, 114172, 2022 | 42 | 2022 |
An in Vivo Nanosensor Measures Compartmental Doxorubicin Exposure JD Harvey, RM Williams, KM Tully, HA Baker, Y Shamay, DA Heller Nano letters 19 (7), 4343-4354, 2019 | 41 | 2019 |
Multivalent display of quinic acid based ligands for targeting E-selectin expressing cells Y Shamay, D Paulin, G Ashkenasy, A David Journal of medicinal chemistry 52 (19), 5906-5915, 2009 | 33 | 2009 |
Pro‐apoptotic peptide‐polymer conjugates to induce mitochondrial‐dependent cell death L Adar, Y Shamay, G Journo, A David Polymers for Advanced Technologies 22 (1), 199-208, 2011 | 29 | 2011 |
Laser-induced thermal response and controlled release of copper oxide nanoparticles from multifunctional polymeric nanocarriers I Maor, S Asadi, S Korganbayev, D Dahis, Y Shamay, E Schena, H Azhari, ... Science and Technology of Advanced Materials 22 (1), 218-233, 2021 | 27 | 2021 |
Assessing the therapeutic efficacy of VEGFR-1-targeted polymer drug conjugates in mouse tumor models Y Shamay, M Golan, D Tyomkin, A David Journal of Controlled Release 229, 192-199, 2016 | 24 | 2016 |
Intra-colonic administration of a polymer-bound NIRF probe for improved colorectal cancer detection during colonoscopy I Kogan-Zviagin, Y Shamay, A Nissan, O Sella-Tavor, M Golan, A David Journal of controlled release 192, 182-191, 2014 | 22 | 2014 |
Complexation of Cell-Penetrating Peptide–Polymer Conjugates with Polyanions Controls Cells Uptake of HPMA Copolymers and Anti-Tumor Activity Y Shamay, L Shpirt, G Ashkenasy, A David Pharmaceutical research 31, 768-779, 2014 | 20 | 2014 |