Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10269), 99-111, 2021 | 5369 | 2021 |
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four … M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10277), 881-891, 2021 | 1346 | 2021 |
Patient outcomes after hospitalisation with COVID-19 and implications for follow-up: results from a prospective UK cohort DT Arnold, FW Hamilton, A Milne, AJ Morley, J Viner, M Attwood, A Noel, ... Thorax 76 (4), 399-401, 2021 | 689 | 2021 |
The Streptococcuspneumoniae Capsule Inhibits Complement Activity and Neutrophil Phagocytosis by Multiple Mechanisms C Hyams, E Camberlein, JM Cohen, K Bax, JS Brown Infection and immunity 78 (2), 704-715, 2010 | 581 | 2010 |
Streptococcus pneumoniae Resistance to Complement-Mediated Immunity Is Dependent on the Capsular Serotype C Hyams, J Yuste, K Bax, E Camberlein, JN Weiser, JS Brown Infection and immunity 78 (2), 716-725, 2010 | 157 | 2010 |
Effectiveness of BNT162b2 and ChAdOx1 nCoV-19 COVID-19 vaccination at preventing hospitalisations in people aged at least 80 years: a test-negative, case-control study C Hyams, R Marlow, Z Maseko, J King, L Ward, K Fox, R Heath, A Tuner, ... The Lancet Infectious Diseases 21 (11), 1539-1548, 2021 | 142 | 2021 |
Impaired Opsonization with C3b and Phagocytosis of Streptococcus pneumoniae in Sera from Subjects with Defects in the Classical Complement Pathway J Yuste, A Sen, L Truedsson, G Jönsson, LS Tay, C Hyams, ... Infection and immunity 76 (8), 3761-3770, 2008 | 135 | 2008 |
Protective contributions against invasive Streptococcus pneumoniae pneumonia of antibody and Th17-cell responses to nasopharyngeal colonisation JM Cohen, S Khandavilli, E Camberlein, C Hyams, HE Baxendale, ... PloS one 6 (10), e25558, 2011 | 120 | 2011 |
Severity of Omicron (B. 1.1. 529) and Delta (B. 1.617. 2) SARS-CoV-2 infection among hospitalised adults: a prospective cohort study in Bristol, United Kingdom C Hyams, R Challen, R Marlow, J Nguyen, E Begier, J Southern, J King, ... The Lancet Regional Health–Europe 25, 2023 | 113 | 2023 |
Serological cross reactivity to CMV and EBV causes problems in the diagnosis of acute hepatitis E virus infection C Hyams, DA Mabayoje, R Copping, D Maranao, M Patel, W Labbett, ... Journal of medical virology 86 (3), 478-483, 2014 | 108 | 2014 |
Streptococcus pneumoniae capsular serotype invasiveness correlates with the degree of factor H binding and opsonization with C3b/iC3b C Hyams, K Trzcinski, E Camberlein, DM Weinberger, S Chimalapati, ... Infection and immunity 81 (1), 354-363, 2013 | 102 | 2013 |
Changes in capsular serotype alter the surface exposure of pneumococcal adhesins and impact virulence CJ Sanchez, CA Hinojosa, P Shivshankar, C Hyams, E Camberlein, ... PloS one 6 (10), e26587, 2011 | 71 | 2011 |
Priming innate immune responses to infection by cyclooxygenase inhibition kills antibiotic-susceptible and-resistant bacteria MJ Stables, J Newson, SS Ayoub, J Brown, CJ Hyams, DW Gilroy Blood, The Journal of the American Society of Hematology 116 (16), 2950-2959, 2010 | 69 | 2010 |
The Effects of PspC on Complement-Mediated Immunity to Streptococcus pneumoniae Vary with Strain Background and Capsular Serotype J Yuste, S Khandavilli, N Ansari, K Muttardi, L Ismail, C Hyams, J Weiser, ... Infection and immunity 78 (1), 283-292, 2010 | 57 | 2010 |
A prospective study of early removal of the urethral catheter after colorectal surgery in patients having epidural analgesia as part of the Enhanced Recovery After Surgery … BM Stubbs, KJM Badcock, C Hyams, FE Rizal, S Warren, D Francis Colorectal Disease 15 (6), 733-736, 2013 | 51 | 2013 |
Roles of the alternative complement pathway and C1q during innate immunity to Streptococcus pyogenes J Yuste, S Ali, S Sriskandan, C Hyams, M Botto, JS Brown The Journal of Immunology 176 (10), 6112-6120, 2006 | 49 | 2006 |
Assessing the effectiveness of BNT162b2 and ChAdOx1nCoV-19 COVID-19 vaccination in prevention of hospitalisations in elderly and frail adults: a single centre test negative … C Hyams, R Marlow, Z Maseko, J King, L Ward, K Fox, R Heath, A Turner, ... | 48 | 2021 |
Characterization of a New Mouse Model of Empyema and the Mechanisms of Pleural Invasion by Streptococcus pneumoniae S Wilkosz, LA Edwards, S Bielsa, C Hyams, A Taylor, RJO Davies, ... American Journal of Respiratory Cell and Molecular Biology 46 (2), 180-187, 2012 | 48 | 2012 |
Effects of Streptococcus pneumoniae strain background on complement resistance C Hyams, S Opel, W Hanage, J Yuste, K Bax, B Henriques-Normark, ... PloS one 6 (10), e24581, 2011 | 45 | 2011 |
Importance of bacterial replication and alveolar macrophage-independent clearance mechanisms during early lung infection with Streptococcus pneumoniae E Camberlein, JM Cohen, R José, CJ Hyams, R Callard, S Chimalapati, ... Infection and immunity 83 (3), 1181-1189, 2015 | 42 | 2015 |