Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with β-tubulin: relevance to Huntington's disease G Hoffner, P Kahlem, P Djian Journal of cell science 115 (5), 941-948, 2002 | 252 | 2002 |
Purification of neuronal inclusions of patients with Huntington's disease reveals a broad range of N‐terminal fragments of expanded huntingtin and insoluble polymers G Hoffner, ML Island, P Djian Journal of neurochemistry 95 (1), 125-136, 2005 | 107 | 2005 |
Oligomeric and polymeric aggregates formed by proteins containing expanded polyglutamine S Iuchi, G Hoffner, P Verbeke, P Djian, H Green Proceedings of the National Academy of Sciences 100 (5), 2409-2414, 2003 | 89 | 2003 |
Protein aggregation in Huntington’s disease G Hoffner, P Djian Biochimie 84 (4), 273-278, 2002 | 74 | 2002 |
Polyglutamine aggregation in Huntington disease: does structure determine toxicity? G Hoffner, P Djian Molecular neurobiology 52, 1297-1314, 2015 | 73 | 2015 |
Monomeric, oligomeric and polymeric proteins in huntington disease and other diseases of polyglutamine expansion G Hoffner, P Djian Brain sciences 4 (1), 91-122, 2014 | 65 | 2014 |
Aggregation of expanded huntingtin in the brains of patients with Huntington disease G Hoffner, S Souès, P Djian Prion 1 (1), 26-31, 2007 | 57 | 2007 |
Structure of inclusions of Huntington’s disease brain revealed by synchrotron infrared microspectroscopy: polymorphism and relevance to cytotoxicity W Andre, C Sandt, P Dumas, P Djian, G Hoffner Analytical Chemistry 85 (7), 3765-3773, 2013 | 51 | 2013 |
Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones E Rousseau, R Kojima, G Hoffner, P Djian, A Bertolotti Journal of Biological Chemistry 284 (3), 1917-1929, 2009 | 48 | 2009 |
Transglutaminase and diseases of the central nervous system G Hoffner, P Djian Front Biosci 10, 3078-3092, 2005 | 39 | 2005 |
Synchrotron-based infrared spectroscopy brings to light the structure of protein aggregates in neurodegenerative diseases G Hoffner, W André, C Sandt, P Djian Reviews in Analytical Chemistry 33 (4), 231-243, 2014 | 20 | 2014 |
Identification of brain substrates of transglutaminase by functional proteomics supports its role in neurodegenerative diseases W André, I Nondier, M Valensi, F Guillonneau, C Federici, G Hoffner, ... Neurobiology of Disease 101, 40-58, 2017 | 17 | 2017 |
The end product of transglutaminase crosslinking: Simultaneous quantitation of [Nε-(γ-glutamyl) lysine] and lysine by HPLC–MS3 G Hoffner, G Van Der Rest, PM Dansette, P Djian Analytical biochemistry 384 (2), 296-304, 2009 | 15 | 2009 |
Transglutaminase in Epidermis and Neurological Disease or What Makes a Good Cross‐Linking Substrate G Hoffner, A Van Houtteghem, W André, P Djian Advances in Enzymology: And Related Areas of Molecular Biology 78, 97-160, 2011 | 9 | 2011 |
[Nε‐(γ‐glutamyl) lysine] as a potential biomarker in neurological diseases : New detection method and fragmentation pathways G Hoffner, Y Hoppilliard, G van Der Rest, P Dansette, P Djian, ... Journal of mass spectrometry 43 (4), 456-469, 2008 | 9 | 2008 |
Transglutaminase-catalyzed crosslinking in neurological disease: from experimental evidence to therapeutic inhibition G Hoffner, W Andre, A Vanhoutteghem, S Soues, P Djian CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2010 | 8 | 2010 |
Inclusions of R6/2 mice are not amyloid and differ structurally from those of Huntington disease brain W André, C Sandt, I Nondier, P Djian, G Hoffner Analytical chemistry 89 (10), 5201-5209, 2017 | 3 | 2017 |
Transglutaminase in neurological disease G Hoffner, P Djian Oncotarget 8 (34), 55772, 2017 | 2 | 2017 |
Transient brain activity dynamics discriminate levels of consciousness during anesthesia S Ensel, L Uhrig, A Ozkirli, G Hoffner, J Tasserie, S Dehaene, ... Communications Biology 7 (1), 716, 2024 | 1 | 2024 |
Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness H Guylaine, C Pablo, U Lynn, S Camilo Miguel, D Morgan, T Jordy, ... eLife (Reviewed preprint), 2024 | | 2024 |