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Guylaine Hoffner
Guylaine Hoffner
INSERM Researcher
在 inserm.fr 的电子邮件经过验证
标题
引用次数
引用次数
年份
Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with β-tubulin: relevance to Huntington's disease
G Hoffner, P Kahlem, P Djian
Journal of cell science 115 (5), 941-948, 2002
2522002
Purification of neuronal inclusions of patients with Huntington's disease reveals a broad range of N‐terminal fragments of expanded huntingtin and insoluble polymers
G Hoffner, ML Island, P Djian
Journal of neurochemistry 95 (1), 125-136, 2005
1072005
Oligomeric and polymeric aggregates formed by proteins containing expanded polyglutamine
S Iuchi, G Hoffner, P Verbeke, P Djian, H Green
Proceedings of the National Academy of Sciences 100 (5), 2409-2414, 2003
892003
Protein aggregation in Huntington’s disease
G Hoffner, P Djian
Biochimie 84 (4), 273-278, 2002
742002
Polyglutamine aggregation in Huntington disease: does structure determine toxicity?
G Hoffner, P Djian
Molecular neurobiology 52, 1297-1314, 2015
732015
Monomeric, oligomeric and polymeric proteins in huntington disease and other diseases of polyglutamine expansion
G Hoffner, P Djian
Brain sciences 4 (1), 91-122, 2014
652014
Aggregation of expanded huntingtin in the brains of patients with Huntington disease
G Hoffner, S Souès, P Djian
Prion 1 (1), 26-31, 2007
572007
Structure of inclusions of Huntington’s disease brain revealed by synchrotron infrared microspectroscopy: polymorphism and relevance to cytotoxicity
W Andre, C Sandt, P Dumas, P Djian, G Hoffner
Analytical Chemistry 85 (7), 3765-3773, 2013
512013
Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones
E Rousseau, R Kojima, G Hoffner, P Djian, A Bertolotti
Journal of Biological Chemistry 284 (3), 1917-1929, 2009
482009
Transglutaminase and diseases of the central nervous system
G Hoffner, P Djian
Front Biosci 10, 3078-3092, 2005
392005
Synchrotron-based infrared spectroscopy brings to light the structure of protein aggregates in neurodegenerative diseases
G Hoffner, W André, C Sandt, P Djian
Reviews in Analytical Chemistry 33 (4), 231-243, 2014
202014
Identification of brain substrates of transglutaminase by functional proteomics supports its role in neurodegenerative diseases
W André, I Nondier, M Valensi, F Guillonneau, C Federici, G Hoffner, ...
Neurobiology of Disease 101, 40-58, 2017
172017
The end product of transglutaminase crosslinking: Simultaneous quantitation of [Nε-(γ-glutamyl) lysine] and lysine by HPLC–MS3
G Hoffner, G Van Der Rest, PM Dansette, P Djian
Analytical biochemistry 384 (2), 296-304, 2009
152009
Transglutaminase in Epidermis and Neurological Disease or What Makes a Good Cross‐Linking Substrate
G Hoffner, A Van Houtteghem, W André, P Djian
Advances in Enzymology: And Related Areas of Molecular Biology 78, 97-160, 2011
92011
[Nε‐(γ‐glutamyl) lysine] as a potential biomarker in neurological diseases : New detection method and fragmentation pathways
G Hoffner, Y Hoppilliard, G van Der Rest, P Dansette, P Djian, ...
Journal of mass spectrometry 43 (4), 456-469, 2008
92008
Transglutaminase-catalyzed crosslinking in neurological disease: from experimental evidence to therapeutic inhibition
G Hoffner, W Andre, A Vanhoutteghem, S Soues, P Djian
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2010
82010
Inclusions of R6/2 mice are not amyloid and differ structurally from those of Huntington disease brain
W André, C Sandt, I Nondier, P Djian, G Hoffner
Analytical chemistry 89 (10), 5201-5209, 2017
32017
Transglutaminase in neurological disease
G Hoffner, P Djian
Oncotarget 8 (34), 55772, 2017
22017
Transient brain activity dynamics discriminate levels of consciousness during anesthesia
S Ensel, L Uhrig, A Ozkirli, G Hoffner, J Tasserie, S Dehaene, ...
Communications Biology 7 (1), 716, 2024
12024
Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness
H Guylaine, C Pablo, U Lynn, S Camilo Miguel, D Morgan, T Jordy, ...
eLife (Reviewed preprint), 2024
2024
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