| Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling N Myeku, CL Clelland, S Emrani, NV Kukushkin, WH Yu, AL Goldberg, ... Nature medicine 22 (1), 46-53, 2016 | 446 | 2016 |
| Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo EE Congdon, JW Wu, N Myeku, YH Figueroa, M Herman, PS Marinec, ... Autophagy 8 (4), 609-622, 2012 | 338 | 2012 |
| Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62 N Myeku, ME Figueiredo-Pereira Journal of Biological Chemistry 286 (25), 22426-22440, 2011 | 270 | 2011 |
| Proteasome–caspase–cathepsin sequence leading to tau pathology induced by prostaglandin J2 in neuronal cells LT Arnaud, N Myeku, ME Figueiredo‐Pereira Journal of neurochemistry 110 (1), 328-342, 2009 | 73 | 2009 |
| Targeting the 26S proteasome to protect against proteotoxic diseases N Myeku, KE Duff Trends in molecular medicine 24 (1), 18-29, 2018 | 61 | 2018 |
| Noncoding translation mitigation JS Kesner, Z Chen, P Shi, AO Aparicio, MR Murphy, Y Guo, A Trehan, ... Nature 617 (7960), 395-402, 2023 | 59 | 2023 |
| cAMP stimulates the ubiquitin/proteasome pathway in rat spinal cord neurons N Myeku, H Wang, ME Figueiredo-Pereira Neuroscience letters 527 (2), 126-131, 2012 | 44 | 2012 |
| Assessment of proteasome impairment and accumulation/aggregation of ubiquitinated proteins in neuronal cultures N Myeku, MJ Metcalfe, Q Huang, M Figueiredo-Pereira Neurodegeneration: Methods and Protocols, 273-296, 2011 | 44 | 2011 |
| Cilostazol, a phosphodiesterase 3 inhibitor, activates proteasome-mediated proteolysis and attenuates tauopathy and cognitive decline AW Schaler, N Myeku Translational Research 193, 31-41, 2018 | 36 | 2018 |
| PAC1 receptor–mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain AW Schaler, AM Runyan, CL Clelland, EJ Sydney, SL Fowler, ... Science translational medicine 13 (595), eaba7394, 2021 | 33 | 2021 |
| DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1 EK Boamah, A Brekman, M Tomasz, N Myeku, M Figueiredo-Pereira, ... Chemical research in toxicology 23 (7), 1151-1162, 2010 | 27 | 2010 |
| 1′-Acetoxychavicol acetate increases Proteasome Activity by activating cAMP-PKA signaling K Yaku, I Matsui-Yuasa, A Kojima-Yuasa Planta Medica 84 (03), 153-159, 2018 | 6 | 2018 |
| 21 Ubiquitin/Proteasome and Autophagy/Lysosome Pathways: Comparison and Role in Neurodegeneration NMME Figueiredo-Pereira Handbook of neurochemistry and molecular neurobiology, 2009 | 6 | 2009 |
| 5-HT4 receptor agonists treatment reduces tau pathology and behavioral deficit in the PS19 mouse model of tauopathy S Jiang, EJ Sydney, AM Runyan, R Serpe, M Srikanth, HY Figueroa, ... Frontiers in Cellular Neuroscience 18, 1338502, 2024 | 4 | 2024 |
| Investigating changes in the proteostasis capabilities of iPSC‐neurons during development and in FTD using iPSC‐neurons with MAPT mutations G Lines, C Arber, E Preza, CA Leckey, N Myeku, JM Casey, M Perkinton, ... Alzheimer's & Dementia 17, e058308, 2021 | 1 | 2021 |
| GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo AW Schaler, AM Runyan, SL Fowler, HY Figueroa, S Shioda, ... bioRxiv, 2020.01. 21.914135, 2020 | 1 | 2020 |
| O4‐11‐03: Interaction between the ubiquitin proteasome system, autophagy and progressive tauopathy in vivo N Myeku, WH Yu, K Duff Alzheimer's & Dementia 8 (4S_Part_17), P636-P637, 2012 | 1 | 2012 |
| Early Proteasome Gene Downregulation And Impaired Proteasomes Function Underlie Proteostasis Failure In Alzheimer's Disease N Myeku, S Jiang, M Srikanth, R Sherpe, S Yavari, P Gaur, GA Collins, ... bioRxiv, 2025.01. 21.634128, 2025 | | 2025 |
| The role of immunoproteasomes in modulating neuro‐inflammation in Alzheimer’s Disease M Kumar, S Jiang, D Lorman, L David, R Soni, M Kissner, M Yang, ... Alzheimer's & Dementia 20, e086577, 2024 | | 2024 |
| Basic Science and Pathogenesis-Part 2 Z Nashman, A Runyan, E Sydney, N Myeku Alzheimer's & dementia: the journal of the Alzheimer's Association 19, e071413, 2023 | | 2023 |
