Maturation and endosomal targeting of β-site amyloid precursor protein-cleaving enzyme: the Alzheimer's disease β-secretase JT Huse, DS Pijak, GJ Leslie, VMY Lee, RW Doms Journal of Biological Chemistry 275 (43), 33729-33737, 2000 | 568 | 2000 |
Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro EJ Soilleux, LS Morris, G Leslie, J Chehimi, Q Luo, E Levroney, ... Journal of leukocyte biology 71 (3), 445-457, 2002 | 563 | 2002 |
Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR S Pöhlmann, J Zhang, F Baribaud, Z Chen, GJ Leslie, G Lin, ... Journal of virology 77 (7), 4070-4080, 2003 | 560 | 2003 |
DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans S Pöhlmann, EJ Soilleux, F Baribaud, GJ Leslie, LS Morris, J Trowsdale, ... Proceedings of the National Academy of Sciences 98 (5), 2670-2675, 2001 | 449 | 2001 |
Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR G Lin, G Simmons, S Pöhlmann, F Baribaud, H Ni, GJ Leslie, ... Journal of virology 77 (2), 1337-1346, 2003 | 314 | 2003 |
DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus S Pohlmann, F Baribaud, B Lee, GJ Leslie, MD Sanchez, ... Journal of Virology 75 (10), 4664-4672, 2001 | 297 | 2001 |
cis Expression of DC-SIGN Allows for More Efficient Entry of Human and Simian Immunodeficiency Viruses via CD4 and a Coreceptor B Lee, G Leslie, E Soilleux, U O'Doherty, S Baik, E Levroney, ... Journal of virology 75 (24), 12028-12038, 2001 | 258 | 2001 |
Quantitative expression and virus transmission analysis of DC-SIGN on monocyte-derived dendritic cells F Baribaud, S Pöhlmann, G Leslie, F Mortari, RW Doms Journal of virology 76 (18), 9135-9142, 2002 | 150 | 2002 |
Functional and antigenic characterization of human, rhesus macaque, pigtailed macaque, and murine DC-SIGN F Baribaud, S Pöhlmann, T Sparwasser, MTY Kimata, YK Choi, ... Journal of virology 75 (21), 10281-10289, 2001 | 101 | 2001 |
V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies MM Laakso, FH Lee, B Haggarty, C Agrawal, KM Nolan, M Biscone, ... PLoS pathogens 3 (8), e117, 2007 | 97 | 2007 |
DC-SIGN interactions with human immunodeficiency virus: virus binding and transfer are dissociable functions S Pöhlmann, GJ Leslie, TG Edwards, T Macfarlan, JD Reeves, ... Journal of virology 75 (21), 10523-10526, 2001 | 97 | 2001 |
Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo CR Maldini, DT Claiborne, K Okawa, T Chen, DL Dopkin, X Shan, ... Nature medicine 26 (11), 1776-1787, 2020 | 88 | 2020 |
Simian immunodeficiency virus utilizes human and sooty mangabey but not rhesus macaque STRL33 for efficient entry S Pöhlmann, B Lee, S Meister, M Krumbiegel, G Leslie, RW Doms, ... Journal of virology 74 (11), 5075-5082, 2000 | 53 | 2000 |
Potent and broad inhibition of HIV-1 by a peptide from the gp41 heptad repeat-2 domain conjugated to the CXCR4 amino terminus GJ Leslie, J Wang, MW Richardson, BS Haggarty, KL Hua, J Duong, ... PLoS pathogens 12 (11), e1005983, 2016 | 51 | 2016 |
Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions AR Bastian, M Contarino, LD Bailey, R Aneja, DRM Moreira, K Freedman, ... Retrovirology 10, 1-14, 2013 | 46 | 2013 |
Replication-competent variants of human immunodeficiency virus type 2 lacking the V3 loop exhibit resistance to chemokine receptor antagonists G Lin, A Bertolotti-Ciarlet, B Haggarty, J Romano, KM Nolan, GJ Leslie, ... Journal of virology 81 (18), 9956-9966, 2007 | 42 | 2007 |
Amino acid 324 in the simian immunodeficiency virus SIVmac V3 loop can confer CD4 independence and modulate the interaction with CCR5 and alternative coreceptors S Pöhlmann, C Davis, S Meister, GJ Leslie, C Otto, JD Reeves, ... Journal of virology 78 (7), 3223-3232, 2004 | 41 | 2004 |
Alterations in T-Lymphocyte Subpopulations in Type I Diabetes: Exploration of Genetic Influence in Identical Twins C Johnston, L Alviggi, BA Millward, R David, G Leslie, DA Pyke, ... Diabetes 37 (11), 1484-1488, 1988 | 39 | 1988 |
Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry P Acharya, C Dogo-Isonagie, JM LaLonde, SN Lam, GJ Leslie, ... American Chemical Society, 2011 | 37 | 2011 |
Characterization of a human immunodeficiency virus type 1 V3 deletion mutation that confers resistance to CCR5 inhibitors and the ability to use aplaviroc-bound receptor KM Nolan, GQ Del Prete, APO Jordan, B Haggarty, J Romano, GJ Leslie, ... Journal of virology 83 (8), 3798-3809, 2009 | 35 | 2009 |