Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications CC Hernandez, O Zaika, GP Tolstykh, MS Shapiro The Journal of physiology 586 (7), 1811-1821, 2008 | 195 | 2008 |
Oxidative modification of M‐type K+ channels as a mechanism of cytoprotective neuronal silencing N Gamper, O Zaika, Y Li, P Martin, CC Hernandez, MR Perez, AYC Wang, ... The EMBO journal 25 (20), 4996-5004, 2006 | 143 | 2006 |
A Carboxy-terminal Inter-Helix Linker As the Site of Phosphatidylinositol 4,5-Bisphosphate Action on Kv7 (M-type) K+ Channels CC Hernandez, O Zaika, MS Shapiro The Journal of general physiology 132 (3), 361-381, 2008 | 105 | 2008 |
De novo GABRG2 mutations associated with epileptic encephalopathies D Shen, CC Hernandez, W Shen, N Hu, A Poduri, B Shiedley, ... Brain 140 (1), 49-67, 2017 | 102 | 2017 |
Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding J Yu, LE Gimenez, CC Hernandez, Y Wu, AH Wein, GW Han, K McClary, ... Science 368 (6489), 428-433, 2020 | 99 | 2020 |
Homomeric and heteromeric assembly of KCNQ (Kv7) K+ channels assayed by total internal reflection fluorescence/fluorescence resonance energy transfer and patch clamp analysis M Bal, J Zhang, O Zaika, CC Hernandez, MS Shapiro Journal of Biological Chemistry 283 (45), 30668-30676, 2008 | 86 | 2008 |
Epileptic encephalopathy de novo GABRB mutations impair γ‐aminobutyric acid type A receptor function VS Janve, CC Hernandez, KM Verdier, N Hu, RL Macdonald Annals of neurology 79 (5), 806-825, 2016 | 85 | 2016 |
Ca2+/calmodulin disrupts AKAP79/150 interactions with KCNQ (M-Type) K+ channels M Bal, J Zhang, CC Hernandez, O Zaika, MS Shapiro Journal of Neuroscience 30 (6), 2311-2323, 2010 | 85 | 2010 |
A structural look at GABAA receptor mutations linked to epilepsy syndromes CC Hernandez, RL Macdonald Brain research 1714, 234-247, 2019 | 83 | 2019 |
Affinity for phosphatidylinositol 4,5-bisphosphate determines muscarinic agonist sensitivity of Kv7 K+ channels CC Hernandez, B Falkenburger, MS Shapiro Journal of general physiology 134 (5), 437-448, 2009 | 74 | 2009 |
Early occurrence of anti-muscarinic autoantibodies and abnormal vagal modulation in Chagas disease ALP Ribeiro, LED Giménez, CCQ Hernández, ACC de Carvalho, ... International journal of cardiology 117 (1), 59-63, 2007 | 73 | 2007 |
GABRB3 mutation, G32R, associated with childhood absence epilepsy alters α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor expression and channel gating KN Gurba, CC Hernandez, N Hu, RL Macdonald Journal of Biological Chemistry 287 (15), 12083-12097, 2012 | 66 | 2012 |
Atypical gating of M-type potassium channels conferred by mutations in uncharged residues in the S4 region of KCNQ2 causing benign familial neonatal convulsions MV Soldovieri, MR Cilio, F Miceli, G Bellini, EM Del Giudice, P Castaldo, ... Journal of Neuroscience 27 (18), 4919-4928, 2007 | 65 | 2007 |
Human antibodies with muscarinic activity modulate ventricular repolarization: basis for electrical disturbance E Medei, RC Pedrosa, PRB Barbosa, PC Costa, CC Hernández, ... International journal of cardiology 115 (3), 373-380, 2007 | 61 | 2007 |
A de novo missense mutation of GABRB2 causes early myoclonic encephalopathy A Ishii, JQ Kang, CC Schornak, CC Hernandez, W Shen, JC Watkins, ... Journal of medical genetics 54 (3), 202-211, 2017 | 59 | 2017 |
Determinants within the turret and pore-loop domains of KCNQ3 K+ channels governing functional activity O Zaika, CC Hernandez, M Bal, GP Tolstykh, MS Shapiro Biophysical journal 95 (11), 5121-5137, 2008 | 55 | 2008 |
The GABRG2 nonsense mutation, Q40X, associated with Dravet syndrome activated NMD and generated a truncated subunit that was partially rescued by aminoglycoside-induced stop … X Huang, M Tian, CC Hernandez, N Hu, RL Macdonald Neurobiology of disease 48 (1), 115-123, 2012 | 54 | 2012 |
Human chagasic IgGs bind to cardiac muscarinic receptors and impair L-type Ca2+ currents CCQ Hernández, LC Barcellos, LED Giménez, RAB Cabarcas, S Garcia, ... Cardiovascular research 58 (1), 55-65, 2003 | 52 | 2003 |
Glycosylation of β2 subunits regulates GABAA receptor biogenesis and channel gating W Lo, AH Lagrange, CC Hernandez, R Harrison, A Dell, SM Haslam, ... Journal of Biological Chemistry 285 (41), 31348-31361, 2010 | 51 | 2010 |
Modulation of Spontaneous and GABA-Evoked Tonic α4β3δ and α4β3γ2L GABAA Receptor Currents by Protein Kinase A X Tang, CC Hernandez, RL Macdonald Journal of neurophysiology 103 (2), 1007-1019, 2010 | 51 | 2010 |