Deubiquitinase-targeting chimeras for targeted protein stabilization NJ Henning, L Boike, JN Spradlin, CC Ward, G Liu, E Zhang, BP Belcher, ... Nature chemical biology 18 (4), 412-421, 2022 | 216 | 2022 |
Highly diastereo-and enantioselective allylboration of aldehydes using α-substituted allyl/crotyl pinacol boronic esters via in situ generated borinic esters JLY Chen, HK Scott, MJ Hesse, CL Willis, VK Aggarwal Journal of the American Chemical Society 135 (14), 5316-5319, 2013 | 131 | 2013 |
Enantioselective rhodium (III)-catalyzed Markovnikov hydroboration of unactivated terminal alkenes JR Smith, BSL Collins, MJ Hesse, MA Graham, EL Myers, VK Aggarwal Journal of the American Chemical Society 139 (27), 9148-9151, 2017 | 127 | 2017 |
Diastereodivergent synthesis of trisubstituted alkenes through protodeboronation of allylic boronic esters: application to the synthesis of the Californian red scale beetle … MJ Hesse, CP Butts, CL Willis, VK Aggarwal Angewandte Chemie International Edition 51 (50), 12444-12448, 2012 | 99 | 2012 |
Rational chemical design of molecular glue degraders ES Toriki, JW Papatzimas, K Nishikawa, D Dovala, AO Frank, MJ Hesse, ... ACS central science 9 (5), 915-926, 2023 | 87 | 2023 |
Highly Selective Allylborations of Aldehydes Using α, α‐Disubstituted Allylic Pinacol Boronic Esters MJ Hesse, S Essafi, CG Watson, JN Harvey, D Hirst, CL Willis, ... Angewandte Chemie 126 (24), 6259-6263, 2014 | 61 | 2014 |
Application of the lithiation–borylation reaction to the rapid and enantioselective synthesis of the bisabolane family of sesquiterpenes VK Aggarwal, LT Ball, S Carobene, RL Connelly, MJ Hesse, BM Partridge, ... Chemical Communications 48 (74), 9230-9232, 2012 | 43 | 2012 |
Targeted protein degradation through E2 recruitment N Forte, D Dovala, MJ Hesse, JM McKenna, JA Tallarico, M Schirle, ... ACS chemical biology 18 (4), 897-904, 2023 | 33 | 2023 |
Discovery of Potent Pyrazoline‐Based Covalent SARS‐CoV‐2 Main Protease Inhibitors P Moon, CM Zammit, Q Shao, D Dovala, L Boike, NJ Henning, M Knapp, ... ChemBioChem 24 (11), e202300116, 2023 | 13 | 2023 |
Full chirality transfer in the synthesis of hindered tertiary boronic esters under in situ lithiation–borylation conditions DJ Blair, S Zhong, MJ Hesse, N Zabaleta, EL Myers, VK Aggarwal Chemical Communications 52 (30), 5289-5292, 2016 | 10 | 2016 |
Angew. Chem., Int M Hesse, S Essafi, C Watson, J Harvey, D Hirst, C Willis, VK Aggarwal | 6 | 2014 |
Identification of Potent, Broad-Spectrum Coronavirus Main Protease Inhibitors for Pandemic Preparedness DT Barkan, K Garland, L Zhang, RT Eastman, M Hesse, M Knapp, ... Journal of medicinal chemistry 67 (19), 17454-17471, 2024 | 2 | 2024 |
Pyrazolopyridine derivatives and uses thereof S Bonazzi, A Cernijenko, JS Cobb, NA Dales, J Dewhurst, MJ Hesse, ... US Patent 11,787,785, 2023 | 1 | 2023 |
Glue degraders and methods of use thereof J Axford, REJ Beckwith, S BONAZZI, N Buschmann, A CERNIJENKO, ... | 1 | 2021 |
PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF S Bonazzi, JS Cobb, NA Dales, MJ Hesse, R Jain, JR Kerrigan, HA Malik, ... US Patent App. 18/826,887, 2025 | | 2025 |
Substituted pyridone compounds useful to treat orthomyxovirus infections GC Bloomfield, MJ Hesse, RY Huang, MR Maser, JC Sutton, BR Taft, ... US Patent App. 18/291,083, 2024 | | 2024 |
Deubiquitinase-targeting chimeras and related methods L Boike, DL Dovala, NJ Henning, MJ Hesse, G Liu, JM McKenna, ... US Patent App. 18/288,550, 2024 | | 2024 |
Pyrazolopyridine Derivatives and Uses thereof S Bonazzi, A Cernijenko, JS Cobb, NA Dales, J Dewhurst, MJ Hesse, ... US Patent App. 18/460,428, 2024 | | 2024 |
Correction to “Rational Chemical Design of Molecular Glue Degraders” ES Toriki, JW Papatzimas, K Nishikawa, D Dovala, AO Frank, MJ Hesse, ... ACS Central Science 9 (8), 1702-1702, 2023 | | 2023 |
Correction to “Rational Chemical Design of Molecular Glue Degraders” DK Nomura, ES Toriki, JW Papatzimas, K Nishikawa, D Dovala, AO Frank, ... ACS Central Science 9 (8), , 1702, 2023 | | 2023 |