Design, synthesis, and biological evaluation of novel 1, 3, 4-thiadiazole derivatives as potential antitumor agents against chronic myelogenous leukemia: Striking effect of … MD Altıntop, HI Ciftci, MO Radwan, B Sever, ZA Kaplancıklı, TFS Ali, ... Molecules 23 (1), 59, 2017 | 75 | 2017 |
1, 2, 4-Triazole/oxime hybrids as new strategy for nitric oxide donors: synthesis, anti-inflammatory, ulceroginicity and antiproliferative activities GEDAA Abuo-Rahma, M Abdel-Aziz, EAM Beshr, TFS Ali European journal of medicinal chemistry 71, 185-198, 2014 | 74 | 2014 |
Cyclodextrin enhances corneal tolerability and reduces ocular toxicity caused by diclofenac H Abdelkader, Z Fathalla, H Moharram, TFS Ali, B Pierscionek Oxidative medicine and cellular longevity 2018 (1), 5260976, 2018 | 62 | 2018 |
New nitric oxide donating 1, 2, 4-triazole/oxime hybrids: synthesis, investigation of anti-inflammatory, ulceroginic liability and antiproliferative activities M Abdel-Aziz, GEDAA Abuo-Rahma, EAM Beshr, TFS Ali Bioorganic & medicinal chemistry 21 (13), 3839-3849, 2013 | 52 | 2013 |
Discovery of novel thienoquinoline-2-carboxamide chalcone derivatives as antiproliferative EGFR tyrosine kinase inhibitors MS Abdelbaset, M Abdel-Aziz, M Ramadan, MH Abdelrahman, ... Bioorganic & Medicinal Chemistry 27 (6), 1076-1086, 2019 | 48 | 2019 |
The first pentacyclic triterpenoid gypsogenin derivative exhibiting anti-ABL1 kinase and anti-chronic myelogenous leukemia activities HI Ciftci, SE Ozturk, TFS Ali, MO Radwan, H Tateishi, R Koga, Z Ocak, ... Biological and Pharmaceutical Bulletin 41 (4), 570-574, 2018 | 43 | 2018 |
Anti-Inflammatory Potential of Green Synthesized Silver Nanoparticles of the Soft Coral Nephthea Sp. Supported by Metabolomics Analysis and Docking Studies OH Abdelhafez, TFS Ali, JR Fahim, SY Desoukey, S Ahmed, FA Behery, ... International journal of nanomedicine, 5345-5360, 2020 | 42 | 2020 |
In vitro and in silico evaluation of anticancer activity of new indole-based 1, 3, 4-oxadiazoles as EGFR and COX-2 inhibitors B Sever, MD Altıntop, A Özdemir, G Akalın Çiftçi, DE Ellakwa, H Tateishi, ... Molecules 25 (21), 5190, 2020 | 36 | 2020 |
Design, synthesis and biological evaluation of pentacyclic triterpene derivatives: Optimization of anti-ABL kinase activity H I. Ciftci, M O. Radwan, S E. Ozturk, NG Ulusoy, E Sozer, D E. Ellakwa, ... Molecules 24 (19), 3535, 2019 | 28 | 2019 |
Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement MO Radwan, HI Ciftci, TFS Ali, DE Ellakwa, R Koga, H Tateishi, A Nakata, ... Molecules 24 (18), 3295, 2019 | 26 | 2019 |
A dithiol compound binds to the zinc finger protein TRAF6 and suppresses its ubiquitination R Koga, MO Radwan, T Ejima, Y Kanemaru, H Tateishi, TFS Ali, HI Ciftci, ... ChemMedChem 12 (23), 1935-1941, 2017 | 25 | 2017 |
Selective SIRT2 inhibitors as promising anticancer therapeutics: An update from 2016 to 2020 E Roshdy, M Mustafa, AER Shaltout, MO Radwan, MAA Ibrahim, ... European Journal of Medicinal Chemistry 224, 113709, 2021 | 22 | 2021 |
New SIRT2 inhibitors: Histidine-based bleomycin spin-off TFS Ali, HI Ciftci, MO Radwan, R Koga, T Ohsugi, Y Okiyama, T Honma, ... Bioorganic & Medicinal Chemistry 27 (9), 1767-1775, 2019 | 22 | 2019 |
Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine-pyridine-histidine system Bioorganic & Medicinal Chemistry, 2015 | 22 | 2015 |
Vanillin-based indolin-2-one derivative bearing a pyridyl moiety as a promising anti-breast cancer agent via anti-estrogenic activity O Bender, I Celik, R Dogan, A Atalay, ME Shoman, TFS Ali, EAM Beshr, ... ACS omega 8 (7), 6968-6981, 2023 | 17 | 2023 |
Discovery of oxindole‐based FLT3 inhibitors as a promising therapeutic lead for acute myeloid leukemia carrying the oncogenic ITD mutation O Bender, ME Shoman, TFS Ali, R Dogan, I Celik, A Mollica, MIA Hamed, ... Archiv der Pharmazie 356 (2), 2200407, 2023 | 16 | 2023 |
Structure activity study of S-trityl-cysteamine dimethylaminopyridine derivatives as SIRT2 inhibitors: Improvement of SIRT2 binding and inhibition MO Radwan, HI Ciftci, TFS Ali, R Koga, H Tateishi, A Nakata, A Ito, ... Bioorganic & Medicinal Chemistry Letters 30 (19), 127458, 2020 | 16 | 2020 |
Applying different techniques to improve the bioavailability of candesartan cilexetil antihypertensive drug UF Aly, HA Sarhan, TFS Ali, HAEB Sharkawy Drug Design, Development and Therapy, 1851-1865, 2020 | 15 | 2020 |
New multi-targeted antiproliferative agents: Design and synthesis of IC261-based oxindoles as potential tubulin, CK1 and EGFR inhibitors MR Fareed, ME Shoman, MIA Hamed, M Badr, HA Bogari, SS Elhady, ... Pharmaceuticals 14 (11), 1114, 2021 | 14 | 2021 |
Neuroprotective effects of a novel carnosine-hydrazide derivative on hippocampal CA1 damage after transient cerebral ischemia K Noguchi, TFS Ali, J Miyoshi, K Orito, T Negoto, T Biswas, N Taira, ... European journal of medicinal chemistry 163, 207-214, 2019 | 14 | 2019 |