| A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline T Jonsson, JK Atwal, S Steinberg, J Snaedal, PV Jonsson, S Bjornsson, ... Nature 488 (7409), 96-99, 2012 | 2206 | 2012 |
| Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target YJ Yu, Y Zhang, M Kenrick, K Hoyte, W Luk, Y Lu, J Atwal, JM Elliott, ... Science translational medicine 3 (84), 84ra44-84ra44, 2011 | 846 | 2011 |
| Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor SJ Mowla, HF Farhadi, S Pareek, JK Atwal, SJ Morris, NG Seidah, ... Journal of Biological Chemistry 276 (16), 12660-12666, 2001 | 778 | 2001 |
| PirB is a functional receptor for myelin inhibitors of axonal regeneration JK Atwal, J Pinkston-Gosse, J Syken, S Stawicki, Y Wu, C Shatz, ... Science 322 (5903), 967-970, 2008 | 642 | 2008 |
| The TrkB-Shc site signals neuronal survival and local axon growth via MEK and PI3-kinase JK Atwal, B Massie, FD Miller, DR Kaplan Neuron 27 (2), 265-277, 2000 | 564 | 2000 |
| EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans V Koprivica, KS Cho, JB Park, G Yiu, J Atwal, B Gore, JA Kim, E Lin, ... Science 310 (5745), 106-110, 2005 | 445 | 2005 |
| p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors RS Aloyz, SX Bamji, CD Pozniak, JG Toma, J Atwal, DR Kaplan, FD Miller The Journal of cell biology 143 (6), 1691-1703, 1998 | 423 | 1998 |
| Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo B Zheng, J Atwal, C Ho, L Case, X He, KC Garcia, O Steward, ... Proceedings of the National Academy of Sciences 102 (4), 1205-1210, 2005 | 391 | 2005 |
| Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates YJ Yu, JK Atwal, Y Zhang, RK Tong, KR Wildsmith, C Tan, N Bien-Ly, ... Science translational medicine 6 (261), 261ra154-261ra154, 2014 | 388 | 2014 |
| An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ O Adolfsson, M Pihlgren, N Toni, Y Varisco, AL Buccarello, K Antoniello, ... Journal of Neuroscience 32 (28), 9677-9689, 2012 | 387 | 2012 |
| A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo JK Atwal, Y Chen, C Chiu, DL Mortensen, WJ Meilandt, Y Liu, CE Heise, ... Science translational medicine 3 (84), 84ra43-84ra43, 2011 | 315 | 2011 |
| Effector-attenuating substitutions that maintain antibody stability and reduce toxicity in mice M Lo, HS Kim, RK Tong, TW Bainbridge, JM Vernes, Y Zhang, YL Lin, ... Journal of Biological Chemistry 292 (9), 3900-3908, 2017 | 292 | 2017 |
| Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein JA Maloney, T Bainbridge, A Gustafson, S Zhang, R Kyauk, P Steiner, ... Journal of Biological Chemistry 289 (45), 30990-31000, 2014 | 229 | 2014 |
| Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons. RS Slack, DJ Belliveau, M Rosenberg, J Atwal, H Lochmüller, R Aloyz, ... The Journal of Cell Biology 135 (4), 1085-1096, 1996 | 163 | 1996 |
| A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death MK Wetzel-Smith, J Hunkapiller, TR Bhangale, K Srinivasan, JA Maloney, ... Nature medicine 20 (12), 1452-1457, 2014 | 158 | 2014 |
| p63 is an essential proapoptotic protein during neural development WB Jacobs, G Govoni, D Ho, JK Atwal, F Barnabe-Heider, WM Keyes, ... Neuron 48 (5), 743-756, 2005 | 156 | 2005 |
| Antibody-mediated targeting of tau in vivo does not require effector function and microglial engagement SH Lee, CE Le Pichon, O Adolfsson, V Gafner, M Pihlgren, H Lin, ... Cell reports 16 (6), 1690-1700, 2016 | 134 | 2016 |
| Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse JK Atwal, KK Singh, M Tessier-Lavigne, FD Miller, DR Kaplan Journal of Neuroscience 23 (20), 7602-7609, 2003 | 126 | 2003 |
| Structure of crenezumab complex with Aβ shows loss of β-hairpin M Ultsch, B Li, T Maurer, M Mathieu, O Adolfsson, A Muhs, A Pfeifer, ... Scientific reports 6 (1), 39374, 2016 | 124 | 2016 |
| Anti-transferrin receptor antibodies and methods of use Y Zhang, JY Zuchero, J Atwal, J Couch, MS Dennis, JA Ernst, RJ Watts, ... US Patent 9,708,406, 2017 | 89 | 2017 |
