Mice long-term high-fat diet feeding recapitulates human cardiovascular alterations: an animal model to study the early phases of diabetic cardiomyopathy SD Calligaris, M Lecanda, F Solis, M Ezquer, J Gutierrez, E Brandan, ... PloS one 8 (4), e60931, 2013 | 181 | 2013 |
Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes L Sobrevia, F Abarzúa, JK Nien, C Salomón, F Westermeier, C Puebla, ... Placenta 32, S159-S164, 2011 | 135 | 2011 |
Insulin restores gestational diabetes mellitus–reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium F Westermeier, C Salomón, M González, C Puebla, E Guzmán-Gutiérrez, ... Diabetes 60 (6), 1677-1687, 2011 | 125 | 2011 |
Fetoplacental vascular endothelial dysfunction as an early phenomenon in the programming of human adult diseases in subjects born from gestational diabetes mellitus or obesity … A Leiva, F Pardo, MA Ramírez, M Farías, P Casanello, L Sobrevia Journal of Diabetes Research 2011 (1), 349286, 2011 | 110 | 2011 |
Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes N Jayabalan, S Nair, Z Nuzhat, GE Rice, FA Zuñiga, L Sobrevia, A Leiva, ... Frontiers in endocrinology 8, 239, 2017 | 107 | 2017 |
Maternal hypercholesterolemia in pregnancy associates with umbilical vein endothelial dysfunction: role of endothelial nitric oxide synthase and arginase II A Leiva, CD de Medina, R Salsoso, T Sáez, S San Martín, F Abarzúa, ... Arteriosclerosis, thrombosis, and vascular biology 33 (10), 2444-2453, 2013 | 93 | 2013 |
Mechanisms regulating hepatic SR-BI expression and their impact on HDL metabolism A Leiva, H Verdejo, ML Benítez, A Martínez, D Busso, A Rigotti Atherosclerosis 217 (2), 299-307, 2011 | 87 | 2011 |
Gestational diabetes reduces adenosine transport in human placental microvascular endothelium, an effect reversed by insulin C Salomon, F Westermeier, C Puebla, P Arroyo, E Guzman-Gutierrez, ... PloS one 7 (7), e40578, 2012 | 81 | 2012 |
Insulin‐stimulated L‐arginine transport requires SLC7A1 gene expression and is associated with human umbilical vein relaxation M Gonzalez, V Gallardo, N Rodríguez, C Salomón, F Westermeier, ... Journal of cellular physiology 226 (11), 2916-2924, 2011 | 79 | 2011 |
Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes-reduced adenosine transport in human umbilical vein endothelium F Westermeier, C Salomón, M Farías, P Arroyo, B Fuenzalida, T Sáez, ... | 69 | 2015 |
Insulin/adenosine axis linked signalling L Silva, M Subiabre, J Araos, T Sáez, R Salsoso, F Pardo, A Leiva, ... Molecular Aspects of Medicine 55, 45-61, 2017 | 67 | 2017 |
Insulin reverses D-glucose–increased nitric oxide and reactive oxygen species generation in human umbilical vein endothelial cells M González, S Rojas, P Avila, L Cabrera, R Villalobos, C Palma, ... PloS one 10 (4), e0122398, 2015 | 67 | 2015 |
Human umbilical vein endothelium-derived exosomes play a role in foetoplacental endothelial dysfunction in gestational diabetes mellitus T Sáez, R Salsoso, A Leiva, F Toledo, P de Vos, M Faas, L Sobrevia Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (2), 499-508, 2018 | 64 | 2018 |
Akt/mTOR role in human foetoplacental vascular insulin resistance in diseases of pregnancy R Villalobos-Labra, L Silva, M Subiabre, J Araos, R Salsoso, ... Journal of Diabetes Research 2017 (1), 5947859, 2017 | 63 | 2017 |
Insulin therapy and fetoplacental vascular function in gestational diabetes mellitus L Sobrevia, R Salsoso, T Sáez, C Sanhueza, F Pardo, A Leiva Experimental Physiology 100 (3), 231-238, 2015 | 63 | 2015 |
Adenosine and preeclampsia R Salsoso, M Farias, J Gutierrez, F Pardo, DI Chiarello, F Toledo, A Leiva, ... Molecular aspects of medicine 55, 126-139, 2017 | 59 | 2017 |
Insulin is a key modulator of fetoplacental endothelium metabolic disturbances in gestational diabetes mellitus L Sobrevia, R Salsoso, B Fuenzalida, E Barros, L Toledo, L Silva, ... Frontiers in Physiology 7, 119, 2016 | 59 | 2016 |
Nitric oxide is a central common metabolite in vascular dysfunction associated with diseases of human pregnancy A Leiva, B Fuenzalida, E Barros, B Sobrevia, R Salsoso, T Saez, ... Current vascular pharmacology 14 (3), 237-259, 2016 | 58 | 2016 |
Role of insulin and adenosine in the human placenta microvascular and macrovascular endothelial cell dysfunction in gestational diabetes mellitus E Guzmán‐Gutiérrez, P Arroyo, R Salsoso, B Fuenzalida, T Sáez, A Leiva, ... Microcirculation 21 (1), 26-37, 2014 | 58 | 2014 |
PDZK1 is required for maintaining hepatic scavenger receptor, class B, type I (SR-BI) steady state levels but not its surface localization or function A Yesilaltay, O Kocher, R Pal, A Leiva, V Quinones, A Rigotti, M Krieger Journal of Biological Chemistry 281 (39), 28975-28980, 2006 | 53 | 2006 |