NAD+ metabolism and its roles in cellular processes during ageing AJ Covarrubias, R Perrone, A Grozio, E Verdin Nature reviews Molecular cell biology 22 (2), 119-141, 2021 | 791 | 2021 |
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ... Nature metabolism 2 (11), 1265-1283, 2020 | 257 | 2020 |
A dynamic G-quadruplex region regulates the HIV-1 long terminal repeat promoter R Perrone, M Nadai, I Frasson, JA Poe, E Butovskaya, TE Smithgall, ... Journal of medicinal chemistry 56 (16), 6521-6530, 2013 | 189 | 2013 |
Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription E Tosoni, I Frasson, M Scalabrin, R Perrone, E Butovskaya, M Nadai, ... Nucleic acids research 43 (18), 8884-8897, 2015 | 153 | 2015 |
The Herpes Simplex Virus-1 genome contains multiple clusters of repeated G-quadruplex: Implications for the antiviral activity of a G-quadruplex ligand S Artusi, M Nadai, R Perrone, MA Biasolo, G Palu, L Flamand, A Calistri, ... Antiviral research 118, 123-131, 2015 | 144 | 2015 |
Anti-HIV-1 activity of the G-quadruplex ligand BRACO-19 R Perrone, E Butovskaya, D Daelemans, G Palu, C Pannecouque, ... Journal of antimicrobial chemotherapy 69 (12), 3248-3258, 2014 | 142 | 2014 |
G-quadruplex forming sequences in the genome of all known human viruses: A comprehensive guide E Lavezzo, M Berselli, I Frasson, R Perrone, G Palù, AR Brazzale, ... PLoS computational biology 14 (12), e1006675, 2018 | 127 | 2018 |
Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity R Perrone, M Nadai, JA Poe, I Frasson, M Palumbo, G Palu, TE Smithgall, ... PloS one 8 (8), e73121, 2013 | 124 | 2013 |
Synthesis, binding and antiviral properties of potent core-extended naphthalene diimides targeting the HIV-1 long terminal repeat promoter G-quadruplexes R Perrone, F Doria, E Butovskaya, I Frasson, S Botti, M Scalabrin, S Lago, ... Journal of medicinal chemistry 58 (24), 9639-9652, 2015 | 105 | 2015 |
Visualization of DNA G-quadruplexes in herpes simplex virus 1-infected cells S Artusi, R Perrone, S Lago, P Raffa, E Di Iorio, G Palu, SN Richter Nucleic acids research 44 (21), 10343-10353, 2016 | 91 | 2016 |
Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome B De Nicola, CJ Lech, B Heddi, S Regmi, I Frasson, R Perrone, ... Nucleic acids research 44 (13), 6442-6451, 2016 | 88 | 2016 |
Mapping and characterization of G-quadruplexes in Mycobacterium tuberculosis gene promoter regions R Perrone, E Lavezzo, E Riello, R Manganelli, G Palù, S Toppo, ... Scientific reports 7 (1), 5743, 2017 | 87 | 2017 |
The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes M Scalabrin, I Frasson, E Ruggiero, R Perrone, E Tosoni, S Lago, ... Scientific reports 7 (1), 45244, 2017 | 72 | 2017 |
The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell R Perrone, E Butovskaya, S Lago, A Garzino-Demo, C Pannecouque, ... International journal of antimicrobial agents 47 (4), 311-316, 2016 | 62 | 2016 |
A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging F Doria, M Nadai, M Zuffo, R Perrone, M Freccero, SN Richter Chemical communications 53 (14), 2268-2271, 2017 | 57 | 2017 |
A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication S Callegaro, R Perrone, M Scalabrin, F Doria, G Palù, SN Richter Scientific reports 7 (1), 2341, 2017 | 48 | 2017 |
Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses R Perrone, E Lavezzo, G Palù, SN Richter Scientific reports 7 (1), 2018, 2017 | 39 | 2017 |
Antiviral activity of the G-quadruplex ligand TMPyP4 against herpes simplex virus-1 S Artusi, E Ruggiero, M Nadai, B Tosoni, R Perrone, A Ferino, I Zanin, ... Viruses 13 (2), 196, 2021 | 37 | 2021 |
Stable and conserved G-quadruplexes in the long terminal repeat promoter of retroviruses E Ruggiero, M Tassinari, R Perrone, M Nadai, SN Richter ACS infectious diseases 5 (7), 1150-1159, 2019 | 29 | 2019 |
Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer A Lopergolo, R Perrone, M Tortoreto, F Doria, GL Beretta, V Zuco, ... Oncotarget 7 (31), 49649, 2016 | 23 | 2016 |