Blood–brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy A Galstyan, JL Markman, ES Shatalova, A Chiechi, AJ Korman, R Patil, ... Nature Communications 10 (1), 3850, 2019 | 231 | 2019 |
Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: what should be the policy? B Kateb, K Chiu, KL Black, V Yamamoto, B Khalsa, JY Ljubimova, H Ding, ... Neuroimage 54, S106-S124, 2011 | 227 | 2011 |
Inhibition of brain tumor growth by intravenous poly (β-L-malic acid) nanobioconjugate with pH-dependent drug release H Ding, S Inoue, AV Ljubimov, R Patil, J Portilla-Arias, J Hu, B Konda, ... Proceedings of the National Academy of Sciences 107 (42), 18143-18148, 2010 | 197 | 2010 |
Brain tumor tandem targeting using a combination of monoclonal antibodies attached to biopoly (β-L-malic acid) M Fujita, BS Lee, NM Khazenzon, ML Penichet, KA Wawrowsky, R Patil, ... Journal of Controlled Release 122 (3), 356-363, 2007 | 114 | 2007 |
Cellular delivery of doxorubicin via pH-controlled hydrazone linkage using multifunctional nano vehicle based on poly (β-L-malic acid) R Patil, J Portilla-Arias, H Ding, B Konda, A Rekechenetskiy, S Inoue, ... International Journal of Molecular Sciences 13 (9), 11681-11693, 2012 | 106 | 2012 |
Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly (β-L-malic acid) R Patil, J Portilla-Arias, H Ding, S Inoue, B Konda, J Hu, KA Wawrowsky, ... Pharmaceutical research 27, 2317-2329, 2010 | 99 | 2010 |
MRI virtual biopsy and treatment of brain metastatic tumors with targeted nanobioconjugates: nanoclinic in the brain R Patil, AV Ljubimov, PR Gangalum, H Ding, J Portilla-Arias, S Wagner, ... ACS nano 9 (5), 5594-5608, 2015 | 91 | 2015 |
Nanobiopolymer for direct targeting and inhibition of EGFR expression in triple negative breast cancer S Inoue, R Patil, J Portilla-Arias, H Ding, B Konda, A Espinoza, D Mongayt, ... PLoS One 7 (2), e31070, 2012 | 75 | 2012 |
Blockade of a laminin-411–notch axis with CRISPR/Cas9 or a nanobioconjugate inhibits glioblastoma growth through tumor-microenvironment cross-talk T Sun, R Patil, A Galstyan, D Klymyshyn, H Ding, A Chesnokova, ... Cancer research 79 (6), 1239-1251, 2019 | 71 | 2019 |
Coarse particulate matter (PM2.5–10) in Los Angeles Basin air induces expression of inflammation and cancer biomarkers in rat brains JY Ljubimova, O Braubach, R Patil, A Chiechi, J Tang, A Galstyan, ... Scientific reports 8 (1), 5708, 2018 | 71 | 2018 |
HER2-positive breast cancer targeting and treatment by a peptide-conjugated mini nanodrug H Ding, PR Gangalum, A Galstyan, I Fox, R Patil, P Hubbard, R Murali, ... Nanomedicine: Nanotechnology, Biology and Medicine 13 (2), 631-639, 2017 | 68 | 2017 |
The optimization of polymalic acid peptide copolymers for endosomolytic drug delivery H Ding, J Portilla-Arias, R Patil, KL Black, JY Ljubimova, E Holler Biomaterials 32 (22), 5269-5278, 2011 | 67 | 2011 |
Polymalic acid–based nanobiopolymer provides efficient systemic breast cancer treatment by inhibiting both HER2/neu receptor synthesis and activity S Inoue, H Ding, J Portilla-Arias, J Hu, B Konda, M Fujita, A Espinoza, ... Cancer research 71 (4), 1454-1464, 2011 | 65 | 2011 |
Phosphodiesterase type 5 inhibitors increase Herceptin transport and treatment efficacy in mouse metastatic brain tumor models J Hu, JY Ljubimova, S Inoue, B Konda, R Patil, H Ding, A Espinoza, ... PloS one 5 (4), e10108, 2010 | 61 | 2010 |
Toxicity and efficacy evaluation of multiple targeted polymalic acid conjugates for triple-negative breast cancer treatment JY Ljubimova, J Portilla-Arias, R Patil, H Ding, S Inoue, JL Markman, ... Journal of drug targeting 21 (10), 956-967, 2013 | 57 | 2013 |
Curcumin targeted, polymalic acid‐based MRI contrast agent for the detection of Aβ plaques in Alzheimer's disease R Patil, PR Gangalum, S Wagner, J Portilla‐Arias, H Ding, ... Macromolecular bioscience 15 (9), 1212-1217, 2015 | 54 | 2015 |
Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme ST Chou, R Patil, A Galstyan, PR Gangalum, WK Cavenee, FB Furnari, ... Journal of Controlled Release 244, 14-23, 2016 | 43 | 2016 |
Polymalic acid chlorotoxin nanoconjugate for near-infrared fluorescence guided resection of glioblastoma multiforme R Patil, A Galstyan, T Sun, ES Shatalova, P Butte, AN Mamelak, C Carico, ... Biomaterials 206, 146-159, 2019 | 39 | 2019 |
Distinct mechanisms of membrane permeation induced by two polymalic acid copolymers H Ding, J Portilla-Arias, R Patil, KL Black, JY Ljubimova, E Holler Biomaterials 34 (1), 217-225, 2013 | 32 | 2013 |
Polymalic acid-based nano biopolymers for targeting of multiple tumor markers: an opportunity for personalized medicine? JY Ljubimova, H Ding, J Portilla-Arias, R Patil, PR Gangalum, ... JoVE (Journal of Visualized Experiments), e50668, 2014 | 27 | 2014 |