Efficient low-cost chromatin profiling with CUT&Tag HS Kaya-Okur, DH Janssens, JG Henikoff, K Ahmad, S Henikoff Nature protocols 15 (10), 3264-3283, 2020 | 223 | 2020 |
Pioneer factor-nucleosome binding events during differentiation are motif encoded MP Meers, DH Janssens, S Henikoff Molecular cell 75 (3), 562-575. e5, 2019 | 122 | 2019 |
Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs DH Janssens, SJ Wu, JF Sarthy, MP Meers, CH Myers, JM Olson, ... Epigenetics & chromatin 11, 1-14, 2018 | 65 | 2018 |
Earmuff restricts progenitor cell potential by attenuating the competence to respond to self-renewal factors DH Janssens, H Komori, D Grbac, K Chen, CT Koe, H Wang, CY Lee Development 141 (5), 1036-1046, 2014 | 57 | 2014 |
Max deletion destabilizes MYC protein and abrogates Eµ-Myc lymphomagenesis H Mathsyaraja, B Freie, PF Cheng, E Babaeva, JT Catchpole, D Janssens, ... Genes & development 33 (17-18), 1252-1264, 2019 | 53 | 2019 |
Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia DH Janssens, MP Meers, SJ Wu, E Babaeva, S Meshinchi, JF Sarthy, ... Nature genetics 53 (11), 1586-1596, 2021 | 47 | 2021 |
Histone deposition pathways determine the chromatin landscapes of H3. 1 and H3. 3 K27M oncohistones JF Sarthy, MP Meers, DH Janssens, JG Henikoff, H Feldman, ... Elife 9, e61090, 2020 | 47 | 2020 |
CUT&Tag2for1: a modified method for simultaneous profiling of the accessible and silenced regulome in single cells DH Janssens, DJ Otto, MP Meers, M Setty, K Ahmad, S Henikoff Genome biology 23 (1), 81, 2022 | 38 | 2022 |
Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth MD Nyquist, LS Ang, A Corella, IM Coleman, MP Meers, AJ Christiani, ... The Journal of clinical investigation 131 (10), 2021 | 34 | 2021 |
An Hdac1/Rpd3-poised circuit balances continual self-renewal and rapid restriction of developmental potential during asymmetric stem cell division DH Janssens, DC Hamm, L Anhezini, Q Xiao, KH Siller, SE Siegrist, ... Developmental Cell 40 (4), 367-380. e7, 2017 | 32 | 2017 |
Multifactorial profiling of epigenetic landscapes at single-cell resolution using MulTI-Tag MP Meers, G Llagas, DH Janssens, CA Codomo, S Henikoff Nature Biotechnology 41 (5), 708-716, 2023 | 31 | 2023 |
Trithorax maintains the functional heterogeneity of neural stem cells through the transcription factor buttonhead H Komori, Q Xiao, DH Janssens, Y Dou, CY Lee Elife 3, e03502, 2014 | 25 | 2014 |
It takes two to tango, a dance between the cells of origin and cancer stem cells in the Drosophila larval brain DH Janssens, CY Lee Seminars in Cell & Developmental Biology 28, 63-69, 2014 | 23 | 2014 |
Nucleosome patterns in circulating tumor DNA reveal transcriptional regulation of advanced prostate cancer phenotypes N De Sarkar, RD Patton, AL Doebley, B Hanratty, M Adil, AJ Kreitzman, ... Cancer discovery 13 (3), 632-653, 2023 | 20 | 2023 |
Biparental contributions of the H2A.B histone variant control embryonic development in mice A Molaro, AJ Wood, D Janssens, SM Kindelay, MT Eickbush, S Wu, ... PLoS Biology 18 (12), e3001001, 2020 | 16 | 2020 |
A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency E Hsieh, DH Janssens, PJ Paddison, EP Browne, S Henikoff, M OhAinle, ... PLoS Pathogens 19 (1), e1011101, 2023 | 13 | 2023 |
CUT&RUN: Targeted in situ genome-wide profiling with high efficiency for low cell numbers D Janssens, S Henikoff | 13 | 2019 |
Sequential activation of transcriptional repressors promotes progenitor commitment by silencing stem cell identity genes N Rives-Quinto, H Komori, CM Ostgaard, DH Janssens, S Kondo, Q Dai, ... Elife 9, e56187, 2020 | 11 | 2020 |
Multifactorial chromatin regulatory landscapes at single cell resolution MP Meers, G Llagas, DH Janssens, CA Codomo, S Henikoff bioRxiv, 2021.07. 08.451691, 2021 | 10 | 2021 |
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations HN Thirimanne, F Wu, DH Janssens, J Swanger, A Diab, HM Feldman, ... Elife 11, e74338, 2022 | 6 | 2022 |