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Derek H. Janssens
Derek H. Janssens
Postdoctoral Fellow, Fred Hutch Cancer Center
在 fredhutch.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Efficient low-cost chromatin profiling with CUT&Tag
HS Kaya-Okur, DH Janssens, JG Henikoff, K Ahmad, S Henikoff
Nature protocols 15 (10), 3264-3283, 2020
2232020
Pioneer factor-nucleosome binding events during differentiation are motif encoded
MP Meers, DH Janssens, S Henikoff
Molecular cell 75 (3), 562-575. e5, 2019
1222019
Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs
DH Janssens, SJ Wu, JF Sarthy, MP Meers, CH Myers, JM Olson, ...
Epigenetics & chromatin 11, 1-14, 2018
652018
Earmuff restricts progenitor cell potential by attenuating the competence to respond to self-renewal factors
DH Janssens, H Komori, D Grbac, K Chen, CT Koe, H Wang, CY Lee
Development 141 (5), 1036-1046, 2014
572014
Max deletion destabilizes MYC protein and abrogates Eµ-Myc lymphomagenesis
H Mathsyaraja, B Freie, PF Cheng, E Babaeva, JT Catchpole, D Janssens, ...
Genes & development 33 (17-18), 1252-1264, 2019
532019
Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia
DH Janssens, MP Meers, SJ Wu, E Babaeva, S Meshinchi, JF Sarthy, ...
Nature genetics 53 (11), 1586-1596, 2021
472021
Histone deposition pathways determine the chromatin landscapes of H3. 1 and H3. 3 K27M oncohistones
JF Sarthy, MP Meers, DH Janssens, JG Henikoff, H Feldman, ...
Elife 9, e61090, 2020
472020
CUT&Tag2for1: a modified method for simultaneous profiling of the accessible and silenced regulome in single cells
DH Janssens, DJ Otto, MP Meers, M Setty, K Ahmad, S Henikoff
Genome biology 23 (1), 81, 2022
382022
Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth
MD Nyquist, LS Ang, A Corella, IM Coleman, MP Meers, AJ Christiani, ...
The Journal of clinical investigation 131 (10), 2021
342021
An Hdac1/Rpd3-poised circuit balances continual self-renewal and rapid restriction of developmental potential during asymmetric stem cell division
DH Janssens, DC Hamm, L Anhezini, Q Xiao, KH Siller, SE Siegrist, ...
Developmental Cell 40 (4), 367-380. e7, 2017
322017
Multifactorial profiling of epigenetic landscapes at single-cell resolution using MulTI-Tag
MP Meers, G Llagas, DH Janssens, CA Codomo, S Henikoff
Nature Biotechnology 41 (5), 708-716, 2023
312023
Trithorax maintains the functional heterogeneity of neural stem cells through the transcription factor buttonhead
H Komori, Q Xiao, DH Janssens, Y Dou, CY Lee
Elife 3, e03502, 2014
252014
It takes two to tango, a dance between the cells of origin and cancer stem cells in the Drosophila larval brain
DH Janssens, CY Lee
Seminars in Cell & Developmental Biology 28, 63-69, 2014
232014
Nucleosome patterns in circulating tumor DNA reveal transcriptional regulation of advanced prostate cancer phenotypes
N De Sarkar, RD Patton, AL Doebley, B Hanratty, M Adil, AJ Kreitzman, ...
Cancer discovery 13 (3), 632-653, 2023
202023
Biparental contributions of the H2A.B histone variant control embryonic development in mice
A Molaro, AJ Wood, D Janssens, SM Kindelay, MT Eickbush, S Wu, ...
PLoS Biology 18 (12), e3001001, 2020
162020
A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency
E Hsieh, DH Janssens, PJ Paddison, EP Browne, S Henikoff, M OhAinle, ...
PLoS Pathogens 19 (1), e1011101, 2023
132023
CUT&RUN: Targeted in situ genome-wide profiling with high efficiency for low cell numbers
D Janssens, S Henikoff
132019
Sequential activation of transcriptional repressors promotes progenitor commitment by silencing stem cell identity genes
N Rives-Quinto, H Komori, CM Ostgaard, DH Janssens, S Kondo, Q Dai, ...
Elife 9, e56187, 2020
112020
Multifactorial chromatin regulatory landscapes at single cell resolution
MP Meers, G Llagas, DH Janssens, CA Codomo, S Henikoff
bioRxiv, 2021.07. 08.451691, 2021
102021
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations
HN Thirimanne, F Wu, DH Janssens, J Swanger, A Diab, HM Feldman, ...
Elife 11, e74338, 2022
62022
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