| Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome JL Bridgford, SC Xie, SA Cobbold, CFA Pasaje, S Herrmann, T Yang, ... Nature communications 9 (1), 3801, 2018 | 261 | 2018 |
| Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state SE Babbitt, L Altenhofen, SA Cobbold, ES Istvan, C Fennell, C Doerig, ... Proceedings of the National Academy of Sciences 109 (47), E3278-E3287, 2012 | 175 | 2012 |
| Decreased K13 abundance reduces hemoglobin catabolism and proteotoxic stress, underpinning artemisinin resistance T Yang, LM Yeoh, MV Tutor, MW Dixon, PJ McMillan, SC Xie, JL Bridgford, ... Cell reports 29 (9), 2917-2928. e5, 2019 | 136 | 2019 |
| Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism IA Lewis, M Wacker, KL Olszewski, SA Cobbold, KS Baska, A Tan, ... PLoS genetics 10 (1), e1004085, 2014 | 114 | 2014 |
| Activation mechanism of PINK1 ZY Gan, S Callegari, SA Cobbold, TR Cotton, MJ Mlodzianoski, ... Nature 602 (7896), 328-335, 2022 | 97 | 2022 |
| Kinetic flux profiling elucidates two independent acetyl-CoA biosynthetic pathways in Plasmodium falciparum SA Cobbold, AM Vaughan, IA Lewis, HJ Painter, N Camargo, DH Perlman, ... Journal of Biological Chemistry 288 (51), 36338-36350, 2013 | 95 | 2013 |
| Metabolomics-based screening of the malaria box reveals both novel and established mechanisms of action DJ Creek, HH Chua, SA Cobbold, B Nijagal, JI MacRae, BK Dickerman, ... Antimicrobial agents and chemotherapy 60 (11), 6650-6663, 2016 | 90 | 2016 |
| Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite SA Cobbold, JM Santos, A Ochoa, DH Perlman, M Llinás Scientific reports 6 (1), 19722, 2016 | 82 | 2016 |
| Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking K Kennedy, SA Cobbold, E Hanssen, J Birnbaum, NJ Spillman, ... PLoS Biology 17 (7), e3000376, 2019 | 77 | 2019 |
| The natural function of the malaria parasite’s chloroquine resistance transporter SH Shafik, SA Cobbold, K Barkat, SN Richards, NS Lancaster, M Llinás, ... Nature communications 11 (1), 3922, 2020 | 73 | 2020 |
| The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen–encoding var genes GQ Tonkin-Hill, L Trianty, R Noviyanti, HHT Nguyen, BF Sebayang, ... PLoS biology 16 (3), e2004328, 2018 | 73 | 2018 |
| Metabolic Dysregulation Induced in Plasmodium falciparum by Dihydroartemisinin and Other Front-Line Antimalarial Drugs SA Cobbold, HH Chua, B Nijagal, DJ Creek, SA Ralph, MJ McConville The Journal of infectious diseases 213 (2), 276-286, 2016 | 68 | 2016 |
| Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum JK O'Hara, LJ Kerwin, SA Cobbold, J Tai, TA Bedell, PJ Reider, M Llinás PLoS One 9 (4), e94061, 2014 | 61 | 2014 |
| The malaria parasite's lactate transporter PfFNT is the target of antiplasmodial compounds identified in whole cell phenotypic screens SV Hapuarachchi, SA Cobbold, SH Shafik, ASM Dennis, MJ McConville, ... PLoS pathogens 13 (2), e1006180, 2017 | 53 | 2017 |
| Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum BK Dickerman, B Elsworth, SA Cobbold, CQ Nie, MJ McConville, ... Scientific Reports 6 (1), 37502, 2016 | 48 | 2016 |
| Using metabolomics to dissect host–parasite interactions J Kloehn, M Blume, SA Cobbold, EC Saunders, MJ Dagley, ... Current opinion in microbiology 32, 59-65, 2016 | 47 | 2016 |
| Methionine transport in the malaria parasite Plasmodium falciparum SA Cobbold, RE Martin, K Kirk International journal for parasitology 41 (1), 125-135, 2011 | 40 | 2011 |
| A family of dual-activity glycosyltransferase-phosphorylases mediates mannogen turnover and virulence in Leishmania parasites MF Sernee, JE Ralton, TL Nero, LF Sobala, J Kloehn, MA Vieira-Lara, ... Cell host & microbe 26 (3), 385-399. e9, 2019 | 36 | 2019 |
| Sequestration and metabolism of host cell arginine by the intraerythrocytic malaria parasite Plasmodium falciparum SA Cobbold, M Llinás, K Kirk Cellular microbiology 18 (6), 820-830, 2016 | 31 | 2016 |
| Methionine biosynthesis and transport are functionally redundant for the growth and virulence of Salmonella Typhimurium AU Husna, N Wang, SA Cobbold, HJ Newton, DM Hocking, JJ Wilksch, ... Journal of Biological Chemistry 293 (24), 9506-9519, 2018 | 30 | 2018 |
