Engineering the ribosomal DNA in a megabase synthetic chromosome W Zhang, G Zhao, Z Luo, Y Lin, L Wang, Y Guo, A Wang, S Jiang, Q Jiang, ... Science 355 (6329), eaaf3981, 2017 | 231 | 2017 |
Critical roles of long noncoding RNAs in Drosophila spermatogenesis K Wen, L Yang, T Xiong, C Di, D Ma, M Wu, Z Xue, X Zhang, L Long, ... Genome research 26 (9), 1233-1244, 2016 | 157 | 2016 |
3D organization of synthetic and scrambled chromosomes G Mercy, J Mozziconacci, VF Scolari, K Yang, G Zhao, A Thierry, Y Luo, ... Science 355 (6329), eaaf4597, 2017 | 150 | 2017 |
Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES Z Luo, L Wang, Y Wang, W Zhang, Y Guo, Y Shen, L Jiang, Q Wu, ... Nature communications 9 (1), 1930, 2018 | 128 | 2018 |
YeastFab: the design and construction of standard biological parts for metabolic engineering in Saccharomyces cerevisiae Y Guo, J Dong, T Zhou, J Auxillos, T Li, W Zhang, L Wang, Y Shen, Y Luo, ... Nucleic acids research 43 (13), e88-e88, 2015 | 127 | 2015 |
Synthetic genomes W Zhang, LA Mitchell, JS Bader, JD Boeke Annual review of biochemistry 89 (1), 77-101, 2020 | 52 | 2020 |
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions Y Zhao, C Coelho, AL Hughes, L Lazar-Stefanita, S Yang, AN Brooks, ... Cell 186 (24), 5220-5236. e16, 2023 | 42 | 2023 |
On the genetic basis of tail-loss evolution in humans and apes B Xia, W Zhang, G Zhao, X Zhang, J Bai, R Brosh, A Wudzinska, E Huang, ... Nature 626 (8001), 1042-1048, 2024 | 39 | 2024 |
Probing the function of metazoan histones with a systematic library of H3 and H4 mutants W Zhang, X Zhang, Z Xue, Y Li, Q Ma, X Ren, J Zhang, S Yang, L Yang, ... Developmental cell 48 (3), 406-419. e5, 2019 | 30 | 2019 |
Manipulating the 3D organization of the largest synthetic yeast chromosome W Zhang, L Lazar-Stefanita, H Yamashita, MJ Shen, LA Mitchell, ... Molecular Cell 83 (23), 4424-4437. e5, 2023 | 15 | 2023 |
Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function J Luo, LA Vale-Silva, AR Raghavan, G Mercy, J Heldrich, X Sun, MK Li, ... Cell Genomics 3 (11), 2023 | 15 | 2023 |
Mouse genome rewriting and tailoring of three important disease loci W Zhang, I Golynker, R Brosh, A Fajardo, Y Zhu, AM Wudzinska, ... Nature 623 (7986), 423-431, 2023 | 11 | 2023 |
Context-dependent neocentromere activity in synthetic yeast chromosome VIII S Lauer, J Luo, L Lazar-Stefanita, W Zhang, LH McCulloch, V Fanfani, ... Cell Genomics 3 (11), 2023 | 11 | 2023 |
Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains LH McCulloch, V Sambasivam, AL Hughes, N Annaluru, S Ramalingam, ... Cell Genomics 3 (11), 2023 | 9 | 2023 |
Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy. iScience. 2022; 25 (5): 104223 LB Argueta, LA Lacko, Y Bram, T Tada, L Carrau, AF Rendeiro, T Zhang, ... View this article via, 2022 | 9 | 2022 |
Dissecting PCNA function with a systematically designed mutant library in yeast Q Jiang, W Zhang, C Liu, Y Lin, Q Wu, J Dai Journal of Genetics and Genomics 46 (6), 301-313, 2019 | 6 | 2019 |
Two differentially stable rDNA loci coexist on the same chromosome and form a single nucleolus L Lazar-Stefanita, J Luo, MAB Haase, W Zhang, JD Boeke Proceedings of the National Academy of Sciences 120 (9), e2219126120, 2023 | 4 | 2023 |
Mouse genomic rewriting and tailoring: synthetic Trp53 and humanized ACE2 W Zhang, I Golynker, R Brosh, AM Wudzinska, Y Zhu, L Carrau, ... bioRxiv, 2022.06. 22.495814, 2022 | 3 | 2022 |
Integrative multi-omic profiling of two human decedents receiving pig heart xenografts reveals strong perturbations in early immune-cell and cellular metabolism responses E Schmauch, B Piening, B Xia, C Zhu, J Stern, W Zhang, A Dowdell, ... bioRxiv, 2023.06. 05.543406, 2023 | 1 | 2023 |
A conditional counterselectable Piga knockout in mouse embryonic stem cells for advanced genome writing applications W Zhang, R Brosh, LH McCulloch, Y Zhu, H Ashe, G Ellis, BR Camellato, ... Iscience 25 (6), 2022 | 1 | 2022 |