Endosome-mediated epithelial remodeling downstream of Hedgehog-Gli is required for tracheoesophageal separation T Nasr, P Mancini, SA Rankin, NA Edwards, AP Kenny, JL Kinney, ... Developmental cell 51 (6), 665-674. e6, 2019 | 48* | 2019 |
Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos T Naert, D Tulkens, NA Edwards, M Carron, NI Shaidani, M Wlizla, A Boel, ... Scientific reports 10 (1), 14662, 2020 | 41 | 2020 |
Developmental basis of trachea-esophageal birth defects NA Edwards, V Shacham-Silverberg, L Weitz, PS Kingma, Y Shen, ... Developmental biology 477, 85-97, 2021 | 34 | 2021 |
Dynamic regulation of connexins in stem cell pluripotency JL Esseltine, CR Brooks, NA Edwards, M Subasri, J Sampson, C Séguin, ... Stem Cells 38 (1), 52-66, 2020 | 21 | 2020 |
Treatment with AICAR inhibits blastocyst development, trophectoderm differentiation and tight junction formation and function in mice MD Calder, NA Edwards, DH Betts, AJ Watson MHR: Basic science of reproductive medicine 23 (11), 771-785, 2017 | 17 | 2017 |
P66Shc, a key regulator of metabolism and mitochondrial ROS production, is dysregulated by mouse embryo culture NA Edwards, AJ Watson, DH Betts Molecular Human Reproduction, 2016 | 17 | 2016 |
Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas G Zhong, P Ahimaz, NA Edwards, JJ Hagen, C Faure, Q Lu, P Kingma, ... Human Genetics and Genomics Advances 3 (3), 2022 | 8 | 2022 |
Modeling endoderm development and disease in Xenopus NA Edwards, AM Zorn Current Topics in Developmental Biology 145, 61-90, 2021 | 4 | 2021 |
Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers GR Gipson, K Nolan, C Kattamuri, AP Kenny, Z Agricola, NA Edwards, ... BMC biology 21 (1), 16, 2023 | 3 | 2023 |
Identification and validation of novel candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas G Zhong, P Ahimaz, NA Edwards, JJ Hagen, C Faure, P Kingma, ... medRxiv, 2021.07. 18.21260699, 2021 | 3 | 2021 |
Knockdown of p66Shc alters lineage-associated transcription factor expression in mouse blastocysts NA Edwards, AJ Watson, DH Betts Stem Cells and Development 27 (21), 1479-1493, 2018 | 3 | 2018 |
CD-1 mouse fertility rapidly declines and is accompanied with early pregnancy loss under conventional housing conditions K Crocker, MD Calder, NA Edwards, DH Betts, AJ Watson Theriogenology 108, 245-254, 2018 | 3 | 2018 |
Identification of a β-galactosidase transgene that provides a live-cell marker of transcriptional activity in growing oocytes and embryos N Edwards, R Farookhi, HJ Clarke MHR: Basic science of reproductive medicine 21 (7), 583-593, 2015 | 2 | 2015 |
Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in trachea-esophageal morphogenesis NA Edwards, A Kashyap, A Warren, ZN Agricola, AP Kenny, Y Shen, ... bioRxiv, 2023.10. 11.561909, 2023 | | 2023 |
Disrupted endosomal trafficking of the Vangl-Celsr polarity complex causes congenital anomalies in trachea-esophageal separation. NA Edwards, A Kashyap, A Warren, AP Kenny, Y Shen, WK Chung, ... Biorxiv: the Preprint Server for Biology, 2023 | | 2023 |
Deletion of p66Shc Dysregulates ERK and STAT3 Activity in Mouse Embryonic Stem Cells, Enhancing Their Naive-Like Self-Renewal in the Presence of Leukemia … AM Powell, NA Edwards, H Hunter, P Kiser, AJ Watson, RC Cumming, ... Stem Cells and Development 32 (15-16), 434-449, 2023 | | 2023 |
Discovering the Developmental Basis of Trachea‐Esophageal Birth Defects: Evidence for Endosome‐opathies N Edwards, G Zhong, P Ahimaz, A Kenny, P Kingma, J Wells, Y Shen, ... The FASEB Journal 36, 2022 | | 2022 |
The Role of P66Shc in Mouse Blastocyst Development NA Edwards The University of Western Ontario (Canada), 2018 | | 2018 |
Treatment with AICAR inhibits blastocyst development, trophectodermdifferentiation and tight junction formation and function in mice NA Edwards, DH Betts, AJ Watson | | 2017 |
Characterizing the Oxidative Stress Adaptor Protein p66Shc During Mouse Preimplantation Development NA Edwards, DH Betts, AJ Watson REPRODUCTIVE SCIENCES 22, 126A-126A, 2015 | | 2015 |