| Identification of liver-specific enhancer–promoter activity in the 3′ untranslated region of the wild-type AAV2 genome GJ Logan, AP Dane, CV Hallwirth, CM Smyth, EE Wilkie, AK Amaya, ... Nature genetics 49 (8), 1267-1273, 2017 | 109 | 2017 |
| High-Throughput In Vitro, Ex Vivo, and In Vivo Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction A Westhaus, M Cabanes-Creus, A Rybicki, G Baltazar, RG Navarro, E Zhu, ... Human gene therapy 31 (9-10), 575-589, 2020 | 80 | 2020 |
| Restoring the natural tropism of AAV2 vectors for human liver M Cabanes-Creus, CV Hallwirth, A Westhaus, BH Ng, SHY Liao, E Zhu, ... Science Translational Medicine 12 (560), eaba3312, 2020 | 45 | 2020 |
| Attenuation of heparan sulfate proteoglycan binding enhances in vivo transduction of human primary hepatocytes with AAV2 M Cabanes-Creus, A Westhaus, RG Navarro, G Baltazar, E Zhu, ... Molecular Therapy Methods & Clinical Development 17, 1139-1154, 2020 | 36 | 2020 |
| Codon-optimization of wild-type adeno-associated virus capsid sequences enhances DNA family shuffling while conserving functionality M Cabanes-Creus, SL Ginn, AK Amaya, SHY Liao, A Westhaus, ... Molecular Therapy-Methods & Clinical Development 12, 71-84, 2019 | 33 | 2019 |
| Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8 M Cabanes-Creus, RG Navarro, E Zhu, G Baltazar, SHY Liao, M Drouyer, ... Molecular Therapy Methods & Clinical Development 24, 88-101, 2022 | 26 | 2022 |
| Single amino acid insertion allows functional transduction of murine hepatocytes with human liver tropic AAV capsids M Cabanes-Creus, RG Navarro, SHY Liao, G Baltazar, M Drouyer, E Zhu, ... Molecular Therapy Methods & Clinical Development 21, 607-620, 2021 | 19 | 2021 |
| AAV-p40 bioengineering platform for variant selection based on transgene expression A Westhaus, M Cabanes-Creus, T Jonker, E Sallard, RG Navarro, E Zhu, ... Human Gene Therapy 33 (11-12), 664-682, 2022 | 18 | 2022 |
| Liver splitting during normothermic machine perfusion: a novel method to combine the advantages of both in-situ and ex-vivo techniques NS Lau, M Ly, C Dennis, K Ewenson, H Ly, JL Huang, M Cabanes-Creus, ... HPB 25 (5), 543-555, 2023 | 16 | 2023 |
| Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of adeno-associated virus vectors A Westhaus, M Cabanes-Creus, KL Dilworth, E Zhu, D Salas Gómez, ... Human Gene Therapy 34 (7-8), 273-288, 2023 | 12 | 2023 |
| Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy N Meumann, M Cabanes‐Creus, M Ertelt, RG Navarro, J Lucifora, Q Yuan, ... Hepatology 77 (3), 802-815, 2023 | 12 | 2023 |
| Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution M Cabanes-Creus, RG Navarro, SHY Liao, S Scott, R Carlessi, ... Molecular Therapy Methods & Clinical Development 28, 220-237, 2023 | 8 | 2023 |
| Long-term ex situ normothermic perfusion of human split livers for more than 1 week NS Lau, M Ly, C Dennis, A Jacques, M Cabanes-Creus, S Toomath, ... Nature communications 14 (1), 4755, 2023 | 7 | 2023 |
| Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes CY Kok, S Tsurusaki, M Cabanes-Creus, S Igoor, R Rao, R Skelton, ... Molecular Therapy-Methods & Clinical Development 30, 459-473, 2023 | 6 | 2023 |
| Restoring the natural tropism of AAV2 vectors for human liver. Sci. Transl. Med. 12, eaba3312 M Cabanes-Creus, CV Hallwirth, A Westhaus, BH Ng, SHY Liao, E Zhu, ... | 6 | 2020 |
| Novel AAV engineering technology: identification of improved AAV variants for gene addition and genome engineering in primary human cells M Cabanes Creus UCL (University College London), 2019 | 4 | 2019 |
| Generation of novel cardiac specific AAV vectors by directed evolution in human iPSC derived cardiomyocytes C Kok, S Igoor, R Skelton, J Chong, D Kimberley, M Cabanes-Creus, ... Heart, Lung and Circulation 28, S171-S172, 2019 | 2 | 2019 |
| Ex-vivo normothermic perfusion of human split livers more than 7 days. A unique model to study new therapeutics and increase the number of available organs NS Lau, M Ly, C Dennis, A Jacques, M Cabanes-Creus, S Toomath, ... Transplantation 106 (8 S), 5-5, 2022 | 1 | 2022 |
| Preclinical evaluation of AAV vectors in an ex vivo human whole liver explant confirms the potential of bioengineered AAVs as clinically relevant hepatotropic vectors M Cabanes-Creus, RG Navarro, SHY Liao, NS Lau, M Ly, G Baltazar, ... MOLECULAR THERAPY 30 (4), 387-387, 2022 | 1 | 2022 |
| Novel AAV variants with improved tropism for human Schwann cells M Drouyer, TH Chu, E Labit, F Haase, RG Navarro, D Nazareth, N Rosin, ... Molecular Therapy Methods & Clinical Development 32 (2), 2024 | | 2024 |
