Splicing-related catalysis by protein-free snRNAs S Valadkhan, JL Manley Nature 413 (6857), 701-707, 2001 | 369 | 2001 |
Negative regulation of the interferon response by an interferon-induced long non-coding RNA H Kambara, F Niazi, L Kostadinova, DK Moonka, CT Siegel, AB Post, ... Nucleic acids research 42 (16), 10668-10680, 2014 | 234 | 2014 |
Computational analysis of functional long noncoding RNAs reveals lack of peptide-coding capacity and parallels with 3′ UTRs F Niazi, S Valadkhan Rna 18 (4), 825-843, 2012 | 218 | 2012 |
snRNAs as the catalysts of pre-mRNA splicing S Valadkhan Current opinion in chemical biology 9 (6), 603-608, 2005 | 212 | 2005 |
Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system Y Garcia-Mesa, TR Jay, MA Checkley, B Luttge, C Dobrowolski, ... Journal of neurovirology 23, 47-66, 2017 | 188 | 2017 |
A novel RNA motif mediates the strict nuclear localization of a long noncoding RNA B Zhang, L Gunawardane, F Niazi, F Jahanbani, X Chen, S Valadkhan Molecular and cellular biology 34 (12), 2318-2329, 2014 | 163 | 2014 |
Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir B Das, C Dobrowolski, B Luttge, S Valadkhan, N Chomont, R Johnston, ... Proceedings of the National Academy of Sciences 115 (33), E7795-E7804, 2018 | 153 | 2018 |
Characterization of the catalytic activity of U2 and U6 snRNAs S Valadkhan, JL Manley Rna 9 (7), 892-904, 2003 | 113 | 2003 |
Role of small nuclear RNAs in eukaryotic gene expression S Valadkhan, LS Gunawardane Essays in biochemistry 54, 79-90, 2013 | 98 | 2013 |
The spliceosomal proteome: at the heart of the largest cellular ribonucleoprotein machine S Valadkhan, Y Jaladat Proteomics 10 (22), 4128-4141, 2010 | 95 | 2010 |
The lncRNA BORG drives breast cancer metastasis and disease recurrence AJ Gooding, B Zhang, FK Jahanbani, HL Gilmore, JC Chang, ... Scientific reports 7 (1), 12698, 2017 | 94 | 2017 |
The spliceosome: a ribozyme at heart? S Valadkhan Walter de Gruyter 388 (7), 693-697, 2007 | 88 | 2007 |
Protein-free small nuclear RNAs catalyze a two-step splicing reaction S Valadkhan, A Mohammadi, Y Jaladat, S Geisler Proceedings of the National Academy of Sciences 106 (29), 11901-11906, 2009 | 86 | 2009 |
The lncRNA BORG facilitates the survival and chemoresistance of triple-negative breast cancers AJ Gooding, B Zhang, L Gunawardane, A Beard, S Valadkhan, ... Oncogene 38 (12), 2020-2041, 2019 | 81 | 2019 |
Role of the snRNAs in spliceosomal active site S Valadkhan RNA biology 7 (3), 345-353, 2010 | 72 | 2010 |
Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing S Valadkhan, A Mohammadi, C Wachtel, JL Manley Rna 13 (12), 2300-2311, 2007 | 72 | 2007 |
lncRNA-mediated regulation of the interferon response S Valadkhan, LS Gunawardane Virus research 212, 127-136, 2016 | 69 | 2016 |
Regulation of interferon-stimulated gene BST2 by a lncRNA transcribed from a shared bidirectional promoter H Kambara, L Gunawardane, E Zebrowski, L Kostadinova, R Jobava, ... Frontiers in immunology 5, 676, 2015 | 65 | 2015 |
The spliceosome: caught in a web of shifting interactions S Valadkhan Current opinion in structural biology 17 (3), 310-315, 2007 | 61 | 2007 |
A tertiary interaction detected in a human U2-U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast S VALADKHAN, JL MANLEY Rna 6 (2), 206-219, 2000 | 55 | 2000 |