关注
Kabir A. Khan PhD
Kabir A. Khan PhD
CIHR Banting Postdoctoral Fellow at Sunnybrook Research Institute, University of Toronto
在 sri.utoronto.ca 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Improving immunotherapy outcomes with anti-angiogenic treatments and vice versa
KA Khan, RS Kerbel
Nature Reviews Clinical Oncology 15 (5), 310-324, 2018
5312018
The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression
EJ Haining, J Yang, RL Bailey, K Khan, R Collier, S Tsai, SP Watson, ...
Journal of Biological Chemistry 287 (47), 39753-39765, 2012
1892012
The emerging role of tetraspanin microdomains on endothelial cells
RL Bailey, JM Herbert, K Khan, VL Heath, R Bicknell, MG Tomlinson
Biochemical Society Transactions 39 (6), 1667-1673, 2011
872011
Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface
KA Khan, AJ Naylor, A Khan, PJ Noy, M Mambretti, P Lodhia, J Athwal, ...
Oncogene 36 (44), 6097-6108, 2017
782017
C‐type lectin domain group 14 proteins in vascular biology, cancer and inflammation
KA Khan, JL McMurray, F Mohammed, R Bicknell
The FEBS journal 286 (17), 3299-3332, 2019
722019
Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth
PJ Noy, P Lodhia, K Khan, X Zhuang, DG Ward, AR Verissimo, A Bacon, ...
Oncogene 34 (47), 5821-5831, 2015
672015
Pre-and post-operative anti-PD-L1 plus anti-angiogenic therapies in mouse breast or renal cancer models of micro-or macro-metastatic disease
FTH Wu, P Xu, A Chow, S Man, J Krüger, KA Khan, M Paez-Ribes, ...
British journal of cancer 120 (2), 196-206, 2019
402019
Sprouting angiogenesis is regulated by shedding of the C‐type lectin family 14, member A (CLEC14A) ectodomain, catalyzed by rhomboid‐like 2 protein (RHBDL2)
PJ Noy, RK Swain, K Khan, P Lodhia, R Bicknell
The FASEB Journal 30 (6), 2311-2323, 2016
382016
Tumors resurrect an embryonic vascular program to escape immunity
EJM Huijbers, KA Khan, RS Kerbel, AW Griffioen
Science immunology 7 (67), eabm6388, 2022
362022
Anti-angiogenic alternatives to VEGF blockade
KA Khan, R Bicknell
Clinical & experimental metastasis 33, 197-210, 2016
352016
A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding
J Zuo, CR Willcox, F Mohammed, M Davey, S Hunter, K Khan, A Antoun, ...
Science signaling 10 (481), eaai8904, 2017
342017
Immunostimulatory and anti-tumor metronomic cyclophosphamide regimens assessed in primary orthotopic and metastatic murine breast cancer
KA Khan, JL Ponce de Léon, M Benguigui, P Xu, A Chow, W Cruz-Muñoz, ...
NPJ Breast Cancer 6 (1), 29, 2020
312020
Ang2 inhibitors and Tie2 activators: potential therapeutics in perioperative treatment of early stage cancer
KA Khan, FTH Wu, W Cruz‐Munoz, RS Kerbel
EMBO Molecular Medicine 13 (7), e08253, 2021
292021
Antiangiogenic–immune-checkpoint inhibitor combinations: lessons from phase III clinical trials
HY Kuo, KA Khan, RS Kerbel
Nature Reviews Clinical Oncology, 1-15, 2024
92024
A CD276 antibody guided missile with one warhead and two targets: the tumor and its vasculature
KA Khan, RS Kerbel
Cancer cell 31 (4), 469-471, 2017
92017
A new Tie1 targeted antibody blocks tumor cell extravasation and metastasis
KA Khan, RS Kerbel
EMBO Molecular Medicine 12 (6), e12355, 2020
72020
Inhibitors of the interaction between CLEC14A and multimerin-2 for inhibition of angiogenesis
R Bicknell, P Noy, KA Khan
US Patent 10,808,031, 2020
12020
Investigating the extracellular interactions of the tumour endothelial marker CLEC14A
KA Khan
University of Birmingham, 2016
12016
Inhibitors of the Interaction Between CLEC14A and Multimerin-2 for Inhibition of Angiogenesis
R Bicknell, P Noy, KA Khan
US Patent App. 16/992,497, 2021
2021
Inhibitors
R Bicknell, KA Khan
US Patent App. 16/320,522, 2019
2019
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