Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy T Amano, S Yamasaki, N Yagishita, K Tsuchimochi, H Shin, K Kawahara, ... Genes & development 17 (19), 2436-2449, 2003 | 253 | 2003 |
The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells K Kikuchi, K Kawahara, S Tancharoen, F Matsuda, Y Morimoto, T Ito, ... Journal of Pharmacology and Experimental Therapeutics 329 (3), 865-874, 2009 | 98 | 2009 |
Beyond free radical scavenging: Beneficial effects of edaravone (Radicut) in various diseases K Kikuchi, N Takeshige, N Miura, Y Morimoto, T Ito, S Tancharoen, ... Experimental and Therapeutic Medicine 3 (1), 3-8, 2012 | 97 | 2012 |
Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4 K Kikuchi, S Tancharoen, F Matsuda, KK Biswas, T Ito, Y Morimoto, ... Biochemical and biophysical research communications 390 (4), 1121-1125, 2009 | 94 | 2009 |
B cell-derived vascular endothelial growth factor A promotes lymphangiogenesis and high endothelial venule expansion in lymph nodes B Shrestha, T Hashiguchi, T Ito, N Miura, K Takenouchi, Y Oyama, ... The Journal of Immunology 184 (9), 4819-4826, 2010 | 91 | 2010 |
Microminipig, a non-rodent experimental animal optimized for life science research: novel atherosclerosis model induced by high fat and cholesterol diet H Kawaguchi, N Miyoshi, N Miura, M Fujiki, M Horiuchi, Y Izumi, ... Journal of pharmacological sciences 115 (2), 115-121, 2011 | 88 | 2011 |
Analysing responses to aspirin and clopidogrel by measuring platelet thrombus formation under arterial flow conditions K Hosokawa, T Ohnishi, H Sameshima, N Miura, T Ito, T Koide, ... Thrombosis and haemostasis 109 (01), 102-111, 2013 | 84 | 2013 |
C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264. 7 cells K Kawahara, KK Biswas, M Unoshima, T Ito, K Kikuchi, Y Morimoto, ... Cardiovascular Pathology 17 (3), 129-138, 2008 | 84 | 2008 |
Beyond neurological disease: new targets for edaravone K Kikuchi, H Uchikado, N Miyagi, Y Morimoto, T Ito, S Tancharoen, ... International journal of molecular medicine 28 (6), 899-906, 2011 | 75 | 2011 |
Inflammation-related microRNA expression level in the bovine milk is affected by mastitis YC Lai, T Fujikawa, T Maemura, T Ando, G Kitahara, Y Endo, O Yamato, ... PloS one 12 (5), e0177182, 2017 | 71 | 2017 |
Mechanism of HMGB1 release inhibition from RAW264. 7 cells by oleanolic acid in Prunus mume Sieb. et Zucc. KI Kawahara, T Hashiguchi, K Masuda, AR Saniabadi, K Kikuchi, ... International journal of molecular medicine 23 (5), 615-620, 2009 | 70 | 2009 |
Minocycline attenuates both OGD-induced HMGB1 release and HMGB1-induced cell death in ischemic neuronal injury in PC12 cells K Kikuchi, K Kawahara, KK Biswas, T Ito, S Tancharoen, Y Morimoto, ... Biochemical and biophysical research communications 385 (2), 132-136, 2009 | 65 | 2009 |
Edaravone (Radicut), a free radical scavenger, is a potentially useful addition to thrombolytic therapy in patients with acute ischemic stroke K Kikuchi, N Miura, KI Kawahara, Y Murai, M Morioka, PA Lapchak, ... Biomedical reports 1 (1), 7-12, 2012 | 61 | 2012 |
Potential of the angiotensin receptor blockers (ARBs) telmisartan, irbesartan, and candesartan for inhibiting the HMGB1/RAGE axis in prevention and acute treatment of stroke K Kikuchi, S Tancharoen, T Ito, Y Morimoto-Yamashita, N Miura, ... International Journal of Molecular Sciences 14 (9), 18899-18924, 2013 | 58 | 2013 |
Novel microminipig model of atherosclerosis by high fat and high cholesterol diet, established in Japan N Miyoshi, M Horiuchi, Y Inokuchi, Y Miyamoto, N Miura, S Tokunaga, ... In Vivo 24 (5), 671-680, 2010 | 56 | 2010 |
Investigation of methicillin-resistant Staphylococcus aureus among clinical isolates from humans and animals by culture methods and multiplex PCR MM Rahman, KB Amin, SMM Rahman, A Khair, M Rahman, A Hossain, ... BMC veterinary research 14, 1-6, 2018 | 54 | 2018 |
Potential of edaravone for neuroprotection in neurologic diseases that do not involve cerebral infarction K Kikuchi, KI Kawahara, H Uchikado, N Miyagi, T Kuramoto, T Miyagi, ... Experimental and therapeutic medicine 2 (5), 771-775, 2011 | 51 | 2011 |
Higly durable silica glass, process and apparatus for producing same, and member and apparatus provided with same Y Harada, S Mizutani, S Hashimoto, M Kudoh, N Miura, K Takahashi, ... US Patent App. 10/105,270, 2003 | 51 | 2003 |
Uterine horn torsion in two non‐gravid bitches K Misumi, M Fujiki, N Miura, H Sakamoto Journal of Small Animal Practice 41 (10), 468-471, 2000 | 50 | 2000 |
Multipotency of equine mesenchymal stem cells derived from synovial fluid D Murata, D Miyakoshi, T Hatazoe, N Miura, S Tokunaga, M Fujiki, ... The Veterinary Journal 202 (1), 53-61, 2014 | 48 | 2014 |