Pharmacologic or genetic targeting of glutamine synthetase skews macrophages toward an M1-like phenotype and inhibits tumor metastasis EM Palmieri, A Menga, R Martín-Pérez, A Quinto, C Riera-Domingo, ... Cell reports 20 (7), 1654-1666, 2017 | 294 | 2017 |
ATP-citrate lyase is essential for macrophage inflammatory response V Infantino, V Iacobazzi, F Palmieri, A Menga Biochemical and biophysical research communications 440 (1), 105-111, 2013 | 254 | 2013 |
A key role of the mitochondrial citrate carrier (SLC25A1) in TNFα-and IFNγ-triggered inflammation V Infantino, V Iacobazzi, A Menga, ML Avantaggiati, F Palmieri Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (11 …, 2014 | 206 | 2014 |
Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation EM Palmieri, I Spera, A Menga, V Infantino, V Porcelli, V Iacobazzi, ... Biochimica et Biophysica Acta (BBA) - Bioenergetics 1847 (8), 729–738, 2015 | 98 | 2015 |
Metabolism and TAM functions—it takes two to tango M Mazzone, A Menga, A Castegna The FEBS Journal 285 (4), 700-716, 2018 | 90 | 2018 |
Elements in support of the ‘non-identity’of the PGRMC1 protein with the σ2 receptor C Abate, M Niso, V Infantino, A Menga, F Berardi European journal of pharmacology 758, 16-23, 2015 | 81 | 2015 |
The crowded crosstalk between cancer cells and stromal microenvironment in gynecological malignancies: biological pathways and therapeutic implication R De Nola, A Menga, A Castegna, V Loizzi, G Ranieri, E Cicinelli, ... International journal of molecular sciences 20 (10), 2401, 2019 | 77 | 2019 |
Blockade of glutamine synthetase enhances inflammatory response in microglial cells EM Palmieri, A Menga, A Lebrun, DC Hooper, DA Butterfield, M Mazzone, ... Antioxidants & redox signaling 26 (8), 351-363, 2017 | 75 | 2017 |
Glutamine synthetase: localization dictates outcome A Castegna, A Menga Genes 9 (2), 108, 2018 | 57 | 2018 |
SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency G Punzi, V Porcelli, M Ruggiu, MF Hossain, A Menga, P Scarcia, ... Human Molecular Genetics 27 (3), 499-504, 2018 | 46 | 2018 |
Pharmacological targets of metabolism in disease: opportunities from macrophages A Castegna, R Gissi, A Menga, M Montopoli, M Favia, A Viola, M Canton Pharmacology & Therapeutics 210, 107521, 2020 | 45 | 2020 |
SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism A Menga, E Palmieri, A Cianciulli, V Infantino, M Mazzone, A Scilimati, ... The FEBS Journal, 2017 | 42 | 2017 |
The contribution of the citrate pathway to oxidative stress in Down syndrome P Convertini, A Menga, G Andria, I Scala, A Santarsiero, ... Immunology 149 (4), 423-431, 2016 | 42 | 2016 |
Understanding metal dynamics between cancer cells and macrophages: competition or synergism? M Serra, A Columbano, U Ammarah, M Mazzone, A Menga Frontiers in Oncology 10, 646, 2020 | 39 | 2020 |
Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia E Wyart, MY Hsu, R Sartori, E Mina, V Rausch, ES Pierobon, ... EMBO reports 23 (4), e53746, 2022 | 38 | 2022 |
Cachexia, a systemic disease beyond muscle atrophy E Wyart, LB Bindels, E Mina, A Menga, S Stanga, PE Porporato International journal of molecular sciences 21 (22), 8592, 2020 | 36 | 2020 |
Glutamine synthetase desensitizes differentiated adipocytes to proinflammatory stimuli by raising intracellular glutamine levels EM Palmieri, I Spera, A Menga, V Infantino, V Iacobazzi, A Castegna FEBS letters 588 (24), 4807-4814, 2014 | 34 | 2014 |
Glufosinate constrains synchronous and metachronous metastasis by promoting anti‐tumor macrophages A Menga, M Serra, S Todisco, C Riera‐Domingo, U Ammarah, M Ehling, ... EMBO Molecular Medicine 12 (10), e11210, 2020 | 33 | 2020 |
N‐acetylaspartate release by glutaminolytic ovarian cancer cells sustains protumoral macrophages A Menga, M Favia, I Spera, MC Vegliante, R Gissi, A De Grassi, L Laera, ... EMBO reports 22 (9), e51981, 2021 | 30 | 2021 |
MEF2C exon α: role in gene activation and differentiation V Infantino, P Convertini, A Menga, V Iacobazzi Gene 531 (2), 355-362, 2013 | 28 | 2013 |