TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence HD Skinner, VC Sandulache, TJ Ow, RE Meyn, JS Yordy, BM Beadle, ... Clinical cancer research 18 (1), 290-300, 2012 | 319 | 2012 |
Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1α, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT … HD Skinner, JZ Zheng, J Fang, F Agani, BH Jiang Journal of Biological Chemistry 279 (44), 45643-45651, 2004 | 304 | 2004 |
Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation G Zhou, J Wang, M Zhao, TX Xie, N Tanaka, D Sano, AA Patel, AM Ward, ... Molecular cell 54 (6), 960-974, 2014 | 245 | 2014 |
Association of body composition with survival and locoregional control of radiotherapy-treated head and neck squamous cell carcinoma AJ Grossberg, S Chamchod, CD Fuller, ASR Mohamed, J Heukelom, ... JAMA oncology 2 (6), 782-789, 2016 | 224 | 2016 |
Prostate cancer cell proliferation is influenced by leptin1 P Somasundar, KA Frankenberry, H Skinner, G Vedula, DW McFadden, ... Journal of Surgical Research 118 (1), 71-82, 2004 | 207 | 2004 |
Salvage pembrolizumab added to kinase inhibitor therapy for the treatment of anaplastic thyroid carcinoma PC Iyer, R Dadu, M Gule-Monroe, NL Busaidy, R Ferrarotto, MA Habra, ... Journal for immunotherapy of cancer 6, 1-10, 2018 | 199 | 2018 |
Evolutionary action score of TP53 identifies high-risk mutations associated with decreased survival and increased distant metastases in head and neck cancer DM Neskey, AA Osman, TJ Ow, P Katsonis, T McDonald, SC Hicks, ... Cancer research 75 (7), 1527-1536, 2015 | 167 | 2015 |
Risk of late toxicity in men receiving dose-escalated hypofractionated intensity modulated prostate radiation therapy: results from a randomized trial KE Hoffman, KR Voong, TJ Pugh, H Skinner, LB Levy, V Takiar, S Choi, ... International Journal of Radiation Oncology* Biology* Physics 88 (5), 1074-1084, 2014 | 165 | 2014 |
A novel YAP1 inhibitor targets CSC-enriched radiation-resistant cells and exerts strong antitumor activity in esophageal adenocarcinoma S Song, M Xie, AW Scott, J Jin, L Ma, X Dong, HD Skinner, RL Johnson, ... Molecular cancer therapeutics 17 (2), 443-454, 2018 | 162 | 2018 |
Pathological complete response in patients with esophageal cancer after the trimodality approach: The association with baseline variables and survival—The University of Texas … M Blum Murphy, L Xiao, VR Patel, DM Maru, AM Correa, F G. Amlashi, ... Cancer 123 (21), 4106-4113, 2017 | 155 | 2017 |
Neoadjuvant BRAF-and immune-directed therapy for anaplastic thyroid carcinoma ME Cabanillas, R Ferrarotto, AS Garden, S Ahmed, NL Busaidy, R Dadu, ... Thyroid 28 (7), 945-951, 2018 | 140 | 2018 |
Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer S Honjo, JA Ajani, AW Scott, Q Chen, HD Skinner, J Stroehlein, ... International journal of oncology 45 (2), 567-574, 2014 | 136 | 2014 |
Leptin receptor expression and cell signaling in breast cancer KA Frankenberry, H Skinner, P Somasundar, DW McFadden, ... International journal of oncology 28 (4), 985-993, 2006 | 128 | 2006 |
ALDH-1 expression levels predict response or resistance to preoperative chemoradiation in resectable esophageal cancer patients JA Ajani, X Wang, S Song, A Suzuki, T Taketa, K Sudo, R Wadhwa, ... Molecular oncology 8 (1), 142-149, 2014 | 125 | 2014 |
Metformin use and improved response to therapy in esophageal adenocarcinoma HD Skinner, MR McCurdy, AE Echeverria, SH Lin, JW Welsh, MS O'Reilly, ... Acta Oncologica 52 (5), 1002-1009, 2013 | 123 | 2013 |
Clinical outcomes and patterns of disease recurrence after intensity modulated proton therapy for oropharyngeal squamous carcinoma GB Gunn, P Blanchard, AS Garden, XR Zhu, CD Fuller, AS Mohamed, ... International Journal of Radiation Oncology* Biology* Physics 95 (1), 360-367, 2016 | 122 | 2016 |
Integrative analysis identifies a novel AXL–PI3 Kinase–PD-L1 signaling axis associated with radiation resistance in head and neck cancer HD Skinner, U Giri, LP Yang, M Kumar, Y Liu, MD Story, CR Pickering, ... Clinical Cancer Research 23 (11), 2713-2722, 2017 | 117 | 2017 |
Metformin use and improved response to therapy in rectal cancer HD Skinner, CH Crane, CR Garrett, C Eng, GJ Chang, JM Skibber, ... Cancer medicine 2 (1), 99-107, 2013 | 106 | 2013 |
Importance of surveillance and success of salvage strategies after definitive chemoradiation in patients with esophageal cancer K Sudo, L Xiao, R Wadhwa, H Shiozaki, E Elimova, T Taketa, MA Blum, ... Journal of Clinical Oncology 32 (30), 3400-3405, 2014 | 105 | 2014 |
Evolutionary action score of TP53 coding variants is predictive of platinum response in head and neck cancer patients AA Osman, DM Neskey, P Katsonis, AA Patel, AM Ward, TK Hsu, ... Cancer research 75 (7), 1205-1215, 2015 | 96 | 2015 |