| Thymidylate synthase inhibitors as anticancer agents: from bench to bedside E Chu, MA Callender, MP Farrell, JC Schmitz Cancer chemotherapy and pharmacology 52, 80-89, 2003 | 232 | 2003 |
| Thymidylate synthase: a critical target for cancer chemotherapy MG Rose, MP Farrell, JC Schmitz Clinical colorectal cancer 1 (4), 220-229, 2002 | 185 | 2002 |
| Thymidylate synthase as a translational regulator of cellular gene expression J Liu, JC Schmitz, X Lin, N Tai, W Yan, M Farrell, M Bailly, T Chen, E Chu Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1587 (2-3 …, 2002 | 163 | 2002 |
| The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer C Chung, CC Mader, JC Schmitz, J Atladottir, P Fitchev, ML Cornwell, ... Laboratory investigation 91 (5), 732-743, 2011 | 143 | 2011 |
| Clove extract inhibits tumor growth and promotes cell cycle arrest and apoptosis H Liu, JC Schmitz, J Wei, S Cao, JH Beumer, S Strychor, L Cheng, M Liu, ... Oncology research 21 (5), 247, 2014 | 142 | 2014 |
| Pharmacokinetics of leucovorin metabolites in human plasma as a function of dose administrated orally and intravenously DG Priest, JC Schmitz, MA Bunni, RK Stuart Oxford University Press 83 (24), 1806-1812, 1991 | 103 | 1991 |
| Short interfering RNA–mediated gene silencing of vascular endothelial growth factor: Effects on cellular proliferation in colon cancer cells AL Mulkeen, T Silva, PS Yoo, JC Schmitz, E Uchio, E Chu, C Cha Archives of Surgery 141 (4), 367-374, 2006 | 92 | 2006 |
| Targeting colon cancer with the novel STAT3 inhibitor bruceantinol N Wei, J Li, C Fang, J Chang, V Xirou, NK Syrigos, BJ Marks, E Chu, ... Oncogene 38 (10), 1676-1687, 2019 | 83 | 2019 |
| Protein kinase d as a potential chemotherapeutic target for colorectal cancer N Wei, E Chu, P Wipf, JC Schmitz Molecular cancer therapeutics 13 (5), 1130-1141, 2014 | 76 | 2014 |
| Impact of dietary folic acid on reduced folates in mouse plasma and tissues: relationship to dideazatetrahydrofolate sensitivity JC Schmitz, GB Grlndey, RM Schultz, DG Priest Biochemical pharmacology 48 (2), 319-325, 1994 | 66 | 1994 |
| Regulation of p53 expression in response to 5-fluorouracil in human cancer RKO cells J Ju, JC Schmitz, B Song, K Kudo, E Chu Clinical cancer research 13 (14), 4245-4251, 2007 | 64 | 2007 |
| Translational autoregulation of thymidylate synthase and dihydrofolate reductase N Tai, JC Schmitz, J Liu, X Lin, M Bailly, TM Chen, E Chu Front Biosci 9, 2521-2526, 2004 | 64 | 2004 |
| Small interfering double-stranded RNAs as therapeutic molecules to restore chemosensitivity to thymidylate synthase inhibitor compounds JC Schmitz, T Chen, E Chu Cancer research 64 (4), 1431-1435, 2004 | 49 | 2004 |
| Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer Y Xi, G Nakajima, JC Schmitz, E Chu, J Ju BMC genomics 7, 1-15, 2006 | 48 | 2006 |
| Effect of 2′-O-methyl antisense ORNs on expression of thymidylate synthase in human colon cancer RKO cells JC Schmitz, D Yu, S Agrawal, E Chu Nucleic Acids Research 29 (2), 415-422, 2001 | 48 | 2001 |
| Total Synthesis of (−)-CP2-Disorazole C1 CD Hopkins, JC Schmitz, E Chu, P Wipf Organic letters 13 (15), 4088-4091, 2011 | 45 | 2011 |
| C-Raf is associated with disease progression and cell proliferation in a subset of melanomas LB Jilaveanu, CR Zito, SA Aziz, PJ Conrad, JC Schmitz, M Sznol, ... Clinical Cancer Research 15 (18), 5704-5713, 2009 | 44 | 2009 |
| Identification of critical amino acid residues on human dihydrofolate reductase protein that mediate RNA recognition N Tai, Y Ding, JC Schmitz, E Chu Nucleic acids research 30 (20), 4481-4488, 2002 | 40 | 2002 |
| Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway H Liu, H Liu, Z Zhou, RA Parise, E Chu, JC Schmitz Cell Communication and Signaling 16, 1-12, 2018 | 33 | 2018 |
| Phase I trial of carboplatin and etoposide in combination with panobinostat in patients with lung cancer AA Tarhini, H Zahoor, B Mclaughlin, WE Gooding, JC Schmitz, ... Anticancer research 33 (10), 4475-4481, 2013 | 33 | 2013 |
