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Nicolas Guehl
Nicolas Guehl
Assistant Professor of Radiology and Biomedical Imaging, Yale School of Medicine
在 yale.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue
C Aguero, M Dhaynaut, MD Normandin, AC Amaral, NJ Guehl, ...
Acta neuropathologica communications 7, 1-15, 2019
1252019
Pharmacokinetic evaluation of the tau PET radiotracer 18F-T807 (18F-AV-1451) in human subjects
DW Wooten, NJ Guehl, EE Verwer, TM Shoup, DL Yokell, N Zubcevik, ...
Journal of Nuclear Medicine 58 (3), 484-491, 2017
942017
Discovery of a highly selective glycogen synthase kinase‐3 inhibitor (PF‐04802367) that modulates tau phosphorylation in the brain: Translation for PET neuroimaging
SH Liang, JM Chen, MD Normandin, JS Chang, GC Chang, CK Taylor, ...
Angewandte Chemie International Edition 55 (33), 9601-9605, 2016
832016
Pseudoreference regions for glial imaging with 11C-PBR28: investigation in 2 clinical cohorts
DS Albrecht, MD Normandin, S Shcherbinin, DW Wooten, AJ Schwarz, ...
Journal of Nuclear Medicine 59 (1), 107-114, 2018
512018
Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR
Y Petibon, NJ Guehl, TG Reese, B Ebrahimi, MD Normandin, TM Shoup, ...
Physics in Medicine & Biology 62 (2), 326, 2016
372016
Heat‐induced radiolabeling of nanoparticles for monocyte tracking by PET
MD Normandin, H Yuan, MQ Wilks, HH Chen, JM Kinsella, H Cho, ...
Angewandte Chemie International Edition 54 (44), 13002-13006, 2015
352015
Quantitative in vivo mapping of myocardial mitochondrial membrane potential
NM Alpert, N Guehl, L Ptaszek, M Pelletier-Galarneau, J Ruskin, ...
PloS one 13 (1), e0190968, 2018
342018
Evaluation of pharmacokinetic modeling strategies for in-vivo quantification of tau with the radiotracer [18F]MK6240 in human subjects
NJ Guehl, DW Wooten, DL Yokell, SH Moon, M Dhaynaut, S Katz, ...
European journal of nuclear medicine and molecular imaging 46, 2099-2111, 2019
302019
Impact of 40 Hz transcranial alternating current stimulation on cerebral tau burden in patients with Alzheimer’s disease: a case series
M Dhaynaut, G Sprugnoli, D Cappon, J Macone, JS Sanchez, ...
Journal of Alzheimer's Disease 85 (4), 1667-1676, 2022
292022
Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques
NJ Guehl, KM Ramos-Torres, C Linnman, SH Moon, M Dhaynaut, ...
Journal of Cerebral Blood Flow & Metabolism 41 (7), 1721-1733, 2021
222021
In vivo quantitative mapping of human mitochondrial cardiac membrane potential: a feasibility study
M Pelletier-Galarneau, Y Petibon, C Ma, P Han, SJW Kim, FJ Detmer, ...
European journal of nuclear medicine and molecular imaging 48, 414-420, 2021
172021
Effects of modulating gamma oscillations via 40Hz transcranial alternating current stimulation (tACS) on Tau PET imaging in mild to moderate Alzheimer’s Disease
M Dhaynaut, D Cappon, R Paciorek, J Macone, A Connor, N Guehl, ...
Journal of Nuclear Medicine 61 (supplement 1), 340-340, 2020
162020
[18F]Fluorocholine and [18F]Fluoroacetate PET as Imaging Biomarkers to Assess Phosphatidylcholine and Mitochondrial Metabolism in Preclinical Models of TSC …
EE Verwer, TR Kavanagh, WJ Mischler, Y Feng, K Takahashi, S Wang, ...
Clinical Cancer Research 24 (23), 5925-5938, 2018
152018
Single-scan rest/stress imaging: validation in a porcine model with 18F-Flurpiridaz
NJ Guehl, MD Normandin, DW Wooten, G Rozen, A Sitek, J Ruskin, ...
European journal of nuclear medicine and molecular imaging 44, 1538-1546, 2017
152017
A Bayesian spatial temporal mixtures approach to kinetic parametric images in dynamic positron emission tomography
W Zhu, J Ouyang, Y Rakvongthai, NJ Guehl, DW Wooten, G El Fakhri, ...
Medical physics 43 (3), 1222-1234, 2016
112016
Synthesis and Characterization of [18F]JNJ-46356479 as the First 18F-Labeled PET Imaging Ligand for Metabotropic Glutamate Receptor 2
G Yuan, NJ Guehl, B Zheng, X Qu, SH Moon, M Dhaynaut, TM Shoup, ...
Molecular imaging and biology 23, 527-536, 2021
102021
Kinetic evaluation and assessment of longitudinal changes in reference region and extracerebral [18F]MK-6240 PET uptake
JF Fu, C Lois, J Sanchez, JA Becker, ZB Rubinstein, E Thibault, ...
Journal of Cerebral Blood Flow & Metabolism 43 (4), 581-594, 2023
82023
Evaluation of fluorinated cromolyn derivatives as potential therapeutics for Alzheimer’s disease
TM Shoup, A Griciuc, MD Normandin, L Quinti, LV Walsh, M Dhaynaut, ...
Journal of Alzheimer's Disease 80 (2), 775-786, 2021
82021
PET imaging of mitochondrial function in acute doxorubicin-induced cardiotoxicity: a proof-of-principle study
FJ Detmer, NM Alpert, SH Moon, M Dhaynaut, JL Guerrero, NJ Guehl, ...
Scientific Reports 12 (1), 6122, 2022
72022
Syntheses of [11 C] 2-and [11 C] 3-trifluoromethyl-4-aminopyridine: potential PET radioligands for demyelinating diseases
KM Ramos-Torres, YP Zhou, BY Yang, NJ Guehl, M Sung-Hyun, S Telu, ...
RSC Medicinal Chemistry 11 (10), 1161-1167, 2020
72020
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