Harnessing cerebrospinal fluid circulation for drug delivery to brain tissues GN Kouzehgarani, T Feldsien, HH Engelhard, KK Mirakhur, C Phipps, ... Advanced Drug Delivery Reviews 173, 20-59, 2021 | 55 | 2021 |
Drug-induced reactive oxygen species (ROS) rely on cell membrane properties to exert anticancer effects HR Molavian, A Goldman, CJ Phipps, M Kohandel, BG Wouters, ... Scientific Reports 6 (1), 27439, 2016 | 46 | 2016 |
Quantifying the effects of antiangiogenic and chemotherapy drug combinations on drug delivery and treatment efficacy S Yonucu, D Yιlmaz, C Phipps, MB Unlu, M Kohandel PLoS computational biology 13 (9), e1005724, 2017 | 44 | 2017 |
Pharmacokinetic considerations for antibody-drug conjugates against cancer P Malik, C Phipps, A Edginton, J Blay Pharmaceutical research 34, 2579-2595, 2017 | 41 | 2017 |
Sequential application of a cytotoxic nanoparticle and a PI3K inhibitor enhances antitumor efficacy A Pandey, A Kulkarni, B Roy, A Goldman, S Sarangi, P Sengupta, ... Cancer research 74 (3), 675-685, 2014 | 38 | 2014 |
Mathematical and experimental validation of flux dialysis method: An improved approach to measure unbound fraction for compounds with high protein binding and other challenging … JC Kalvass, C Phipps, GJ Jenkins, P Stuart, X Zhang, L Heinle, ... Drug Metabolism and Disposition 46 (4), 458-469, 2018 | 37 | 2018 |
Mathematical Model of the Effect of Interstitial Fluid Pressure on Angiogenic Behavior in Solid Tumors C Phipps, M Kohandel Computational and mathematical methods in medicine, 2011 | 36 | 2011 |
Population PBPK modelling of trastuzumab: a framework for quantifying and predicting inter-individual variability PRV Malik, A Hamadeh, C Phipps, AN Edginton Journal of pharmacokinetics and pharmacodynamics 44, 277-290, 2017 | 30 | 2017 |
Antibody-drug conjugates as targeted therapies: Are we there yet? A critical review of the current clinical landscape E Tarcsa, MR Guffroy, H Falahatpisheh, C Phipps, JC Kalvass Drug Discovery Today: Technologies 37, 13-22, 2020 | 28 | 2020 |
Mechanistic Modeling of Antibody–Drug Conjugate Internalization at the Cellular Level Reveals Inefficient Processing Steps KR Durbin, C Phipps, X Liao Molecular cancer therapeutics 17 (6), 1341-1351, 2018 | 28 | 2018 |
A microscale mathematical model for metabolic symbiosis: Investigating the effects of metabolic inhibition on ATP turnover in tumors C Phipps, H Molavian, M Kohandel Journal of Theoretical Biology 366, 103-114, 2015 | 22 | 2015 |
Population Physiologically-Based Pharmacokinetic Model Incorporating Lymphatic Uptake for a Subcutaneously Administered Pegylated Peptide E Offman, C Phipps, AN Edginton JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 42, S13-S13, 2015 | 16 | 2015 |
Industry perspective on the pharmacokinetic and absorption, distribution, metabolism, and excretion characterization of heterobifunctional protein degraders LP Volak, HM Duevel, S Humphreys, D Nettleton, C Phipps, A Pike, ... Drug Metabolism and Disposition 51 (7), 792-803, 2023 | 10 | 2023 |
Marcinkiewicz interpolation theorems for Orlicz and Lorentz gamma spaces R Kerman, C Phipps, L Pick Publicacions Matemàtiques 58 (1), 3-30, 2014 | 9 | 2014 |
Combination of Chemotherapy and Antiangiogenic Therapies: A Mathematical Modelling Approach C Phipps University of Waterloo, 2009 | 9 | 2009 |
PBPK model for antibody disposition in mouse brain: validation using large-pore microdialysis data S Wu, F Le Prieult, CJ Phipps, M Mezler, DK Shah Journal of Pharmacokinetics and Pharmacodynamics 49 (6), 579-592, 2022 | 7 | 2022 |
Toward a model of language acquisition threshold H Fukś, C Phipps Proceedings of the 17th IASTED international conference on Modelling and …, 2006 | 6 | 2006 |
On reversible group rings Y Li, HE Bell, C Phipps Bulletin of the Australian Mathematical Society 74 (1), 139-142, 2006 | 6 | 2006 |
Industry perspective on the pharmacokinetic and ADME characterization of heterobifunctional protein degraders LP Volak, HM Duevel, S Humphreys, D Nettleton, C Phipps, A Pike, ... Drug metabolism and disposition, 2023 | 4 | 2023 |
Finite element approximations to rearrangements M Francu, R Kerman, C Phipps, A Sayfy Preprint, 2012 | 2 | 2012 |