A novel channelopathy in pulmonary arterial hypertension L Ma, D Roman-Campos, ED Austin, M Eyries, KS Sampson, F Soubrier, ... New England Journal of Medicine 369 (4), 351-361, 2013 | 581 | 2013 |
Mutation of an A-kinase-anchoring protein causes long-QT syndrome L Chen, ML Marquardt, DJ Tester, KJ Sampson, MJ Ackerman, RS Kass Proceedings of the National Academy of Sciences 104 (52), 20990-20995, 2007 | 438 | 2007 |
Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics C Terrenoire, K Wang, KW Chan Tung, WK Chung, RH Pass, JT Lu, ... Journal of General Physiology 141 (1), 61-72, 2013 | 228 | 2013 |
Autonomic control of cardiac action potentials: role of potassium channel kinetics in response to sympathetic stimulation C Terrenoire, CE Clancy, JW Cormier, KJ Sampson, RS Kass Circulation research 96 (5), e25-e34, 2005 | 206 | 2005 |
Molecular basis of ranolazine block of LQT-3 mutant sodium channels: evidence for site of action S Fredj, KJ Sampson, H Liu, RS Kass British journal of pharmacology 148 (1), 16, 2006 | 204 | 2006 |
Molecular pathophysiology of congenital long QT syndrome MS Bohnen, G Peng, SH Robey, C Terrenoire, V Iyer, KJ Sampson, ... Physiological reviews 97 (1), 89-134, 2017 | 184 | 2017 |
KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate JD Osteen, C Gonzalez, KJ Sampson, V Iyer, S Rebolledo, HP Larsson, ... Proceedings of the National Academy of Sciences 107 (52), 22710-22715, 2010 | 140 | 2010 |
Electrotonic influences on action potential duration dispersion in small hearts: a simulation study KJ Sampson, CS Henriquez American Journal of Physiology-Heart and Circulatory Physiology 289 (1 …, 2005 | 122 | 2005 |
KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps R Barro-Soria, S Rebolledo, SI Liin, ME Perez, KJ Sampson, RS Kass, ... Nature communications 5 (1), 3750, 2014 | 96 | 2014 |
Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels JD Osteen, R Barro-Soria, S Robey, KJ Sampson, RS Kass, HP Larsson Proceedings of the National Academy of Sciences 109 (18), 7103-7108, 2012 | 91 | 2012 |
Unique cardiac Purkinje fiber transient outward current β-subunit composition: a potential molecular link to idiopathic ventricular fibrillation L Xiao, TT Koopmann, B Ördög, PG Postema, AO Verkerk, V Iyer, ... Circulation research 112 (10), 1310-1322, 2013 | 85 | 2013 |
Coupling data mining and laboratory experiments to discover drug interactions causing QT prolongation T Lorberbaum, KJ Sampson, JB Chang, V Iyer, RL Woosley, RS Kass, ... Journal of the American College of Cardiology 68 (16), 1756-1764, 2016 | 82 | 2016 |
Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension MS Bohnen, L Ma, N Zhu, H Qi, C McClenaghan, C Gonzaga-Jauregui, ... Circulation: Genomic and Precision Medicine 11 (10), e002087, 2018 | 77 | 2018 |
A Novel and Lethal De Novo LQT-3 Mutation in a Newborn with Distinct Molecular Pharmacology and Therapeutic Response JR Bankston, M Yue, W Chung, M Spyres, RH Pass, E Silver, ... PLoS One 2 (12), e1258, 2007 | 72 | 2007 |
A computational model of Purkinje fibre single cell electrophysiology: implications for the long QT syndrome KJ Sampson, V Iyer, AR Marks, RS Kass The Journal of physiology 588 (14), 2643-2655, 2010 | 71 | 2010 |
Cardiac delayed rectifier potassium channels in health and disease L Chen, KJ Sampson, RS Kass Cardiac electrophysiology clinics 8 (2), 307-322, 2016 | 69 | 2016 |
Altered Na+ Channels Promote Pause-Induced Spontaneous Diastolic Activity in Long QT Syndrome Type 3 Myocytes S Fredj, N Lindegger, KJ Sampson, P Carmeliet, RS Kass Circulation research 99 (11), 1225-1232, 2006 | 65 | 2006 |
Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry K Wang, C Terrenoire, KJ Sampson, V Iyer, JD Osteen, J Lu, G Keller, ... The Journal of physiology 589 (24), 6093-6104, 2011 | 61 | 2011 |
Simulation and prediction of functional block in the presence of structural and ionic heterogeneity KJ Sampson, CS Henriquez American Journal of Physiology-Heart and Circulatory Physiology 281 (6 …, 2001 | 58 | 2001 |
Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1 PJ Chan, JD Osteen, D Xiong, MS Bohnen, D Doshi, KJ Sampson, ... Journal of General Physiology 139 (2), 135-144, 2012 | 51 | 2012 |