| Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating … P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ... Archives of toxicology 87, 1315-1530, 2013 | 1424 | 2013 |
| Multilineage communication regulates human liver bud development from pluripotency JG Camp, K Sekine, T Gerber, H Loeffler-Wirth, H Binder, M Gac, ... Nature 546 (7659), 533-538, 2017 | 548 | 2017 |
| Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis S Gaul, A Leszczynska, F Alegre, B Kaufmann, CD Johnson, LA Adams, ... Journal of hepatology 74 (1), 156-167, 2021 | 370 | 2021 |
| Cell sources for in vitro human liver cell culture models K Zeilinger, N Freyer, G Damm, D Seehofer, F Knöspel Experimental Biology and Medicine 241 (15), 1684-1698, 2016 | 268 | 2016 |
| Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells P Godoy, W Schmidt-Heck, K Natarajan, B Lucendo-Villarin, D Szkolnicka, ... Journal of hepatology 63 (4), 934-942, 2015 | 197 | 2015 |
| Manufactured nanomaterials: categorization and approaches to hazard assessment T Gebel, H Foth, G Damm, A Freyberger, PJ Kramer, W Lilienblum, C Röhl, ... Archives of toxicology 88, 2191-2211, 2014 | 171 | 2014 |
| Toxicogenomics directory of chemically exposed human hepatocytes M Grinberg, RM Stöber, K Edlund, E Rempel, P Godoy, R Reif, A Widera, ... Archives of toxicology 88, 2261-2287, 2014 | 150 | 2014 |
| Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity L Schyschka, JJM Sánchez, Z Wang, B Burkhardt, U Müller-Vieira, ... Archives of toxicology 87, 1581-1593, 2013 | 149 | 2013 |
| Featured Article: Isolation, characterization, and cultivation of human hepatocytes and non-parenchymal liver cells E Pfeiffer, V Kegel, K Zeilinger, JG Hengstler, AK Nüssler, D Seehofer, ... Experimental biology and medicine 240 (5), 645-656, 2015 | 117 | 2015 |
| Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator–activated receptor alpha (PPARα) M Thomas, O Burk, B Klumpp, BA Kandel, G Damm, TS Weiss, K Klein, ... Molecular pharmacology 83 (3), 709-718, 2013 | 116 | 2013 |
| Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue P Godoy, A Widera, W Schmidt-Heck, G Campos, C Meyer, C Cadenas, ... Archives of toxicology 90, 2513-2529, 2016 | 114 | 2016 |
| Protocol for isolation of primary human hepatocytes and corresponding major populations of non-parenchymal liver cells V Kegel, D Deharde, E Pfeiffer, K Zeilinger, D Seehofer, G Damm Journal of visualized experiments: JoVE, 2016 | 106 | 2016 |
| Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations W Albrecht, F Kappenberg, T Brecklinghaus, R Stoeber, R Marchan, ... Archives of toxicology 93, 1609-1637, 2019 | 104 | 2019 |
| Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma SO Sajadian, S Ehnert, H Vakilian, E Koutsouraki, G Damm, D Seehofer, ... Clinical Epigenetics 7, 1-14, 2015 | 101 | 2015 |
| Involvement of sphingosine 1-phosphate in palmitate-induced insulin resistance of hepatocytes via the S1P2 receptor subtype S Fayyaz, J Henkel, L Japtok, S Krämer, G Damm, D Seehofer, ... Diabetologia 57, 373-382, 2014 | 93 | 2014 |
| A systematic comparison of the impact of inflammatory signaling on absorption, distribution, metabolism, and excretion gene expression and activity in primary human hepatocytes … M Klein, M Thomas, U Hofmann, D Seehofer, G Damm, UM Zanger Drug Metabolism and Disposition 43 (2), 273-283, 2015 | 92 | 2015 |
| Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling K Mleczko-Sanecka, F Roche, A Rita da Silva, D Call, F D’Alessio, ... Blood, The Journal of the American Society of Hematology 123 (10), 1574-1585, 2014 | 84 | 2014 |
| Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control M Brosch, K Kattler, A Herrmann, W von Schönfels, K Nordström, ... Nature communications 9 (1), 4150, 2018 | 83 | 2018 |
| High exposure to inorganic arsenic by food: the need for risk reduction U Gundert-Remy, G Damm, H Foth, A Freyberger, T Gebel, K Golka, ... Archives of Toxicology 89, 2219-2227, 2015 | 82 | 2015 |
| 3D cultivation techniques for primary human hepatocytes A Bachmann, M Moll, E Gottwald, C Nies, R Zantl, H Wagner, B Burkhardt, ... Microarrays 4 (1), 64-83, 2015 | 79 | 2015 |
