Regulation of antitumor immune responses by the IL‐12 family cytokines, IL‐12, IL‐23, and IL‐27 M Xu, I Mizoguchi, N Morishima, Y Chiba, J Mizuguchi, T Yoshimoto Journal of Immunology Research 2010 (1), 832454, 2010 | 238 | 2010 |
Expanding diversity in molecular structures and functions of the IL-6/IL-12 heterodimeric cytokine family H Hasegawa, I Mizoguchi, Y Chiba, M Ohashi, M Xu, T Yoshimoto Frontiers in immunology 7, 479, 2016 | 153 | 2016 |
Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases Y Chiba, I Mizoguchi, H Hasegawa, M Ohashi, N Orii, T Nagai, ... Cellular and molecular life sciences 75, 1363-1376, 2018 | 89 | 2018 |
A Pivotal Role for Interleukin‐27 in CD8+ T Cell Functions and Generation of Cytotoxic T Lymphocytes N Morishima, I Mizoguchi, M Okumura, Y Chiba, M Xu, M Shimizu, ... BioMed Research International 2010 (1), 605483, 2010 | 82 | 2010 |
Promotion of expansion and differentiation of hematopoietic stem cells by interleukin-27 into myeloid progenitors to control infection in emergency myelopoiesis J Furusawa, I Mizoguchi, Y Chiba, M Hisada, F Kobayashi, H Yoshida, ... PLoS pathogens 12 (3), e1005507, 2016 | 71 | 2016 |
Potential clinical application of interleukin‐27 as an antitumor agent T Yoshimoto, Y Chiba, JI Furusawa, M Xu, R Tsunoda, K Higuchi, ... Cancer science 106 (9), 1103-1110, 2015 | 63 | 2015 |
IL-27 suppresses RANKL expression in CD4+ T cells in part through STAT3 S Kamiya, M Okumura, Y Chiba, T Fukawa, C Nakamura, N Nimura, ... Immunology letters 138 (1), 47-53, 2011 | 59 | 2011 |
IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperation with a TLR3 agonist poly (I: C) partly in a TRAIL-dependent manner Y Chiba, I Mizoguchi, K Mitobe, K Higuchi, H Nagai, C Nishigori, ... PloS one 8 (10), e76159, 2013 | 51 | 2013 |
Regulation of the development of acute hepatitis by IL‐23 through IL‐22 and IL‐17 production M Xu, N Morishima, I Mizoguchi, Y Chiba, K Fujita, M Kuroda, Y Iwakura, ... European journal of immunology 41 (10), 2828-2839, 2011 | 50 | 2011 |
Interleukins and cancer immunotherapy T Yoshimoto, N Morishima, M Okumura, Y Chiba, M Xu, J Mizuguchi Immunotherapy 1 (5), 825-844, 2009 | 45 | 2009 |
IL-27 promotes nitric oxide production induced by LPS through STAT1, NF-κB and MAPKs M Shimizu, K Ogura, I Mizoguchi, Y Chiba, K Higuchi, H Ohtsuka, ... Immunobiology 218 (4), 628-634, 2013 | 41 | 2013 |
Interleukin-27 exerts its antitumor effects by promoting differentiation of hematopoietic stem cells to M1 macrophages Y Chiba, I Mizoguchi, J Furusawa, H Hasegawa, M Ohashi, M Xu, T Owaki, ... Cancer Research 78 (1), 182-194, 2018 | 23 | 2018 |
Prediction of chemical respiratory and contact sensitizers by OX40L expression in dendritic cells using a novel 3D coculture system I Mizoguchi, M Ohashi, Y Chiba, H Hasegawa, M Xu, T Owaki, ... Frontiers in Immunology 8, 929, 2017 | 23 | 2017 |
Immunosurveillance markers may predict patients who can discontinue imatinib therapy without relapse T Yoshimoto, I Mizoguchi, S Katagiri, T Tauchi, J Furusawa, Y Chiba, ... Oncoimmunology 3 (5), e28861, 2014 | 18 | 2014 |
EBV-induced gene 3 augments IL-23Rα protein expression through a chaperone calnexin I Mizoguchi, M Ohashi, H Hasegawa, Y Chiba, N Orii, S Inoue, C Kawana, ... The Journal of clinical investigation 130 (11), 6124-6140, 2020 | 7 | 2020 |
Protective effects against tumors and infection by interleukin-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors N Orii, I Mizoguchi, Y Chiba, H Hasegawa, M Ohashi, M Xu, T Nagai, ... OncoImmunology 7 (5), e1421892, 2018 | 4 | 2018 |
Therapeutic potential of interleukin-27 against cancers in preclinical mouse models I Mizoguchi, Y Chiba, J Furusawa, M Xu, R Tsunoda, K Higuchi, ... Oncoimmunology 4 (10), e1042200, 2015 | 4 | 2015 |
Regulation of inflammatory immune responses leading to the development of bone destructive autoimmune disease rheumatoid arthritis by IL-27 T Yoshimoto, M Xu, I Mizuguchi, Y Chiba, S Kamiya, M Matsui, ... Arthritis Research & Therapy 14 (Suppl 1), O21, 2012 | 3 | 2012 |
Immunological control of chronic myeloid leukemia leading to treatment-free remission I Mizoguchi, T Yoshimoto, S Katagiri, J Furusawa, Y Chiba, J Mizuguchi, ... J Hematol Blood Transfus 2 (3), 1024, 2014 | 1 | 2014 |
A Novel Role for Epstein-Barr Virus-Induced Gene 3 as An Intracellular Molecule That Enhances IL-23 Receptor Expression by Binding to Calnexin and IL-23 Receptor I Mizoguchi, Y Chiba, H Hasegawa, M Ohashi, M Xu, T Owaki, ... CYTOKINE 100, 48-49, 2017 | | 2017 |