The anti-diabetic drug metformin protects against chemotherapy-induced peripheral neuropathy in a mouse model QL Mao-Ying, A Kavelaars, K Krukowski, XJ Huo, W Zhou, TJ Price, ... PloS one 9 (6), e100701, 2014 | 190 | 2014 |
MicroRNA-124 as a novel treatment for persistent hyperalgesia HLDM Willemen, XJ Huo, QL Mao-Ying, J Zijlstra, CJ Heijnen, ... Journal of neuroinflammation 9, 1-10, 2012 | 184 | 2012 |
Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1 P Singhmar, XJ Huo, N Eijkelkamp, SR Berciano, F Baameur, FC Mei, ... Proceedings of the National Academy of Sciences 113 (11), 3036-3041, 2016 | 127 | 2016 |
Increased expression of HMGB1 is associated with poor prognosis in human bladder cancer GL Yang, LH Zhang, JJ Bo, XJ Huo, HG Chen, M Cao, DM Liu, YR Huang Journal of surgical oncology 106 (1), 57-61, 2012 | 98 | 2012 |
Prevention of chemotherapy-induced peripheral neuropathy by the small-molecule inhibitor pifithrin-μ K Krukowski, CH Nijboer, XJ Huo, A Kavelaars, CJ Heijnen Pain 156 (11), 2184-2192, 2015 | 81 | 2015 |
Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain G Laumet, W Zhou, R Dantzer, JD Edralin, XJ Huo, DP Budac, ... Brain, behavior, and immunity 66, 94-102, 2017 | 76 | 2017 |
Interleukin-10 resolves pain hypersensitivity induced by cisplatin by reversing sensory neuron hyperexcitability G Laumet, A Bavencoffe, JD Edralin, XJ Huo, ET Walters, R Dantzer, ... Pain 161 (10), 2344-2352, 2020 | 61 | 2020 |
Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment J Ma, XJ Huo, MB Jarpe, A Kavelaars, CJ Heijnen Acta neuropathologica communications 6, 1-14, 2018 | 60 | 2018 |
The fibroblast-derived protein PI16 controls neuropathic pain P Singhmar, RTP Trinh, J Ma, XJ Huo, B Peng, CJ Heijnen, A Kavelaars Proceedings of the National Academy of Sciences 117 (10), 5463-5471, 2020 | 53 | 2020 |
Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy P Singhmar, XJ Huo, Y Li, PM Dougherty, F Mei, X Cheng, CJ Heijnen, ... Pain 159 (5), 884-893, 2018 | 49 | 2018 |
Chemotherapy accelerates age-related development of tauopathy and results in loss of synaptic integrity and cognitive impairment ACA Chiang, X Huo, A Kavelaars, CJ Heijnen Brain, behavior, and immunity 79, 319-325, 2019 | 40 | 2019 |
Cisplatin treatment induces attention deficits and impairs synaptic integrity in the prefrontal cortex in mice XJ Huo, TM Reyes, CJ Heijnen, A Kavelaars Scientific reports 8 (1), 17400, 2018 | 32 | 2018 |
The insulin receptor regulates the persistence of mechanical nociceptive sensitization in flies and mice Y Wang, R Lopez-Bellido, X Huo, A Kavelaars, MJ Galko Biology open 12 (6), bio059864, 2023 | 2 | 2023 |
66. Intrathecal administration of microRNA-124 alleviates both neuropathic pain and depression-like behavior in mice X Huo, Q Mao-Ying, W Zhou, R Dantzer, CJ Heijnen, A Kavelaars Brain, Behavior, and Immunity 32, e19, 2013 | 2 | 2013 |
PI16 is a non-neuronal regulator of neuropathic pain P Singhmar, RTP Trinh, J Ma, XJ Huo, B Peng, CJ Heijnen, A Kavelaars bioRxiv, 696542, 2019 | 1 | 2019 |
67. The AMP-kinase inhibitor metformin inhibits chemotherapy-induced peripheral neuropathy Q Mao-Ying, A Kavelaars, K Krukowski, X Huo, TJ Price, C Cleeland, ... Brain, Behavior, and Immunity 40, e20, 2014 | 1 | 2014 |
109. Pifithrin-μ prevents paclitaxel-induced peripheral neuropathy in a mouse model K Krukowski, XJ Huo, M Ozcan, CH Nijboer, CJ Heijnen, A Kavelaars Brain, Behavior, and Immunity 40, e32, 2014 | 1 | 2014 |
Phosphorylation of Epac1 by GRK2 inhibits Epac1‐Rap1 signaling and prevents chronic pain (802.7) P Singhmar, XJ Huo, S Berciano, D Hawke, X Cheng, F Mei, F Mayor, ... The FASEB Journal 28, 802.7, 2014 | 1 | 2014 |
Genistein induces non-rapid eye movement sleep in mice XJ Huo, W Liu, MH Qiu, ZL Huang, WM Qu Sleep and Biological Rhythms 10, 278-286, 2012 | 1 | 2012 |
Pifithrin-μ verhindert Chemotherapie-induzierte Neuropathie K Krukowski, CH Nijboer, XJ Huo, A Kavelaars, CJ Heijnen Journal Club Schmerzmedizin 5 (01), 29-29, 2016 | | 2016 |