Dynamically driven protein allostery N Popovych, S Sun, RH Ebright, CG Kalodimos Nature structural & molecular biology 13 (9), 831-838, 2006 | 738 | 2006 |
Role of zinc in human islet amyloid polypeptide aggregation JR Brender, K Hartman, RPR Nanga, N Popovych, R de la Salud Bea, ... Journal of the American Chemical Society 132 (26), 8973-8983, 2010 | 265 | 2010 |
Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation IE Wertz, K Newton, D Seshasayee, S Kusam, C Lam, J Zhang, ... Nature 528 (7582), 370-375, 2015 | 261 | 2015 |
Structural basis for cAMP-mediated allosteric control of the catabolite activator protein N Popovych, SR Tzeng, M Tonelli, RH Ebright, CG Kalodimos Proceedings of the National Academy of Sciences 106 (17), 6927-6932, 2009 | 247 | 2009 |
A model of the membrane-bound cytochrome b5-cytochrome P450 complex from NMR and mutagenesis data S Ahuja, N Jahr, SC Im, S Vivekanandan, N Popovych, SV Le Clair, ... Journal of Biological Chemistry 288 (30), 22080-22095, 2013 | 133 | 2013 |
Site specific interaction of the polyphenol EGCG with the SEVI amyloid precursor peptide PAP (248–286) N Popovych, JR Brender, R Soong, S Vivekanandan, K Hartman, ... The Journal of Physical Chemistry B 116 (11), 3650-3658, 2012 | 95 | 2012 |
Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes DS Hewings, J Heideker, TP Ma, AP AhYoung, F El Oualid, A Amore, ... Nature Communications 9 (1), 1162, 2018 | 89 | 2018 |
Bacterial curli protein promotes the conversion of PAP248-286 into the amyloid SEVI: cross-seeding of dissimilar amyloid sequences K Hartman, JR Brender, K Monde, A Ono, ML Evans, N Popovych, ... PeerJ 1, e5, 2013 | 84 | 2013 |
NMR Structure in a Membrane Environment Reveals Putative Amyloidogenic Regions of the SEVI Precursor Peptide PAP248−286 RPR Nanga, JR Brender, S Vivekanandan, N Popovych, A Ramamoorthy Journal of the American Chemical Society 131 (49), 17972-17979, 2009 | 71 | 2009 |
Probing the transmembrane structure and dynamics of microsomal NADPH-cytochrome P450 oxidoreductase by solid-state NMR R Huang, K Yamamoto, M Zhang, N Popovych, I Hung, SC Im, Z Gan, ... Biophysical journal 106 (10), 2126-2133, 2014 | 47 | 2014 |
The amyloidogenic SEVI precursor, PAP248-286, is highly unfolded in solution despite an underlying helical tendency JR Brender, RPR Nanga, N Popovych, R Soong, PM Macdonald, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (4), 1161-1169, 2011 | 40 | 2011 |
Targeted degradation via direct 26S proteasome recruitment C Bashore, S Prakash, MC Johnson, RJ Conrad, IA Kekessie, SJ Scales, ... Nature Chemical Biology 19 (1), 55-63, 2023 | 38 | 2023 |
Incorporating NOE-derived distances in conformer generation of cyclic peptides with distance geometry S Wang, K Krummenacher, GA Landrum, BD Sellers, P Di Lello, ... Journal of Chemical Information and Modeling 62 (3), 472-485, 2022 | 11 | 2022 |
A multifaceted hit-finding approach reveals novel LC3 family ligands M Steffek, E Helgason, N Popovych, L Rougé, JM Bruning, KS Li, ... Biochemistry 62 (3), 633-644, 2022 | 11 | 2022 |
Diagnosing and mitigating method-based avidity artifacts that confound polyubiquitin-binding assays AJ Schoeffler, E Helgason, N Popovych, EC Dueber Biophysical reports 1 (2), 2021 | 3 | 2021 |
Membrane Permeability in a Large Macrocyclic Peptide Driven by a Saddle-Shaped Conformation JH Faris, E Adaligil, N Popovych, S Ono, M Takahashi, H Nguyen, E Plise, ... Journal of the American Chemical Society 146 (7), 4582-4591, 2024 | 1 | 2024 |
Diagnosing and mitigating method-based avidity artifacts that confound polyubiquitin-binding assays AJ Schoeffler, E Helgason, N Popovych, EC Dueber Biophysical Reports 2 (2), 2022 | | 2022 |