Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues X Zhang, DT Odom, SH Koo, MD Conkright, G Canettieri, J Best, H Chen, ... Proceedings of the National Academy of Sciences 102 (12), 4459-4464, 2005 | 1161 | 2005 |
The CREB coactivator TORC2 functions as a calcium-and cAMP-sensitive coincidence detector RA Screaton, MD Conkright, Y Katoh, JL Best, G Canettieri, S Jeffries, ... Cell 119 (1), 61-74, 2004 | 756 | 2004 |
TORCs: transducers of regulated CREB activity MD Conkright, G Canettieri, R Screaton, E Guzman, L Miraglia, ... Molecular cell 12 (2), 413-423, 2003 | 737 | 2003 |
cAMP promotes pancreatic β-cell survival via CREB-mediated induction of IRS2 US Jhala, G Canettieri, RA Screaton, RN Kulkarni, S Krajewski, J Reed, ... Genes & development 17 (13), 1575-1580, 2003 | 696 | 2003 |
Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis M Centanni, L Gargano, G Canettieri, N Viceconti, A Franchi, GD Fave, ... New England Journal of Medicine 354 (17), 1787-1795, 2006 | 398 | 2006 |
Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation G Canettieri, L Di Marcotullio, A Greco, S Coni, L Antonucci, P Infante, ... Nature cell biology 12 (2), 132-142, 2010 | 385 | 2010 |
Hedgehog controls neural stem cells through p53‐independent regulation of Nanog A Po, E Ferretti, E Miele, E De Smaele, A Paganelli, G Canettieri, S Coni, ... The EMBO journal 29 (15), 2646-2658, 2010 | 255 | 2010 |
Attenuation of a phosphorylation-dependent activator by an HDAC–PP1 complex G Canettieri, I Morantte, E Guzmán, H Asahara, S Herzig, SD Anderson, ... Nature Structural & Molecular Biology 10 (3), 175-181, 2003 | 241 | 2003 |
Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB BM Mayr, G Canettieri, MR Montminy Proceedings of the National Academy of Sciences 98 (19), 10936-10941, 2001 | 226 | 2001 |
Gli1/DNA interaction is a druggable target for Hedgehog‐dependent tumors P Infante, M Mori, R Alfonsi, F Ghirga, F Aiello, S Toscano, C Ingallina, ... The EMBO journal 34 (2), 200-217, 2015 | 188 | 2015 |
Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal L Di Marcotullio, A Greco, D Mazzà, G Canettieri, L Pietrosanti, P Infante, ... Oncogene 30 (1), 65-76, 2011 | 138 | 2011 |
Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma A Po, M Silvano, E Miele, C Capalbo, A Eramo, V Salvati, M Todaro, ... Oncogene 36 (32), 4641-4652, 2017 | 106 | 2017 |
Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma E De Smaele, L Di Marcotullio, M Moretti, M Pelloni, MA Occhione, ... Neoplasia 13 (4), 374-IN23, 2011 | 98 | 2011 |
PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress D Mazza, P Infante, V Colicchia, A Greco, R Alfonsi, M Siler, L Antonucci, ... Cell Death & Differentiation 20 (12), 1688-1697, 2013 | 96 | 2013 |
Non-canonical Hedgehog/AMPK-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth D D’Amico, L Antonucci, L Di Magno, S Coni, G Sdruscia, A Macone, ... Developmental cell 35 (1), 21-35, 2015 | 86 | 2015 |
Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling G Canettieri, SH Koo, R Berdeaux, J Heredia, S Hedrick, X Zhang, ... Cell metabolism 2 (5), 331-338, 2005 | 85 | 2005 |
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1 G Canettieri, S Coni, M Della Guardia, V Nocerino, L Antonucci, ... Proceedings of the National Academy of Sciences 106 (5), 1445-1450, 2009 | 80 | 2009 |
Gli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy S Coni, L Antonucci, D D'Amico, L Di Magno, P Infante, E De Smaele, ... PLoS One 8 (6), e65718, 2013 | 79 | 2013 |
Digging a hole under Hedgehog: downstream inhibition as an emerging anticancer strategy L Di Magno, S Coni, L Di Marcotullio, G Canettieri Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1856 (1), 62-72, 2015 | 75 | 2015 |
microRNA‐17‐92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1 N Garg, A Po, E Miele, AF Campese, F Begalli, M Silvano, P Infante, ... The EMBO journal 32 (21), 2819-2832, 2013 | 74 | 2013 |