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Alexander Horspool, PhD.
Alexander Horspool, PhD.
在 boehringer-ingelheim.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Genomic and Phenotypic Diversity among Ten Laboratory Isolates of Pseudomonas aeruginosa PAO1
CE Chandler, AM Horspool, PJ Hill, DJ Wozniak, JW Schertzer, DA Rasko, ...
Journal of bacteriology 201 (5), 10.1128/jb. 00595-18, 2019
862019
Reciprocal cross-species induction of outer membrane vesicle biogenesis via secreted factors
AM Horspool, JW Schertzer
Scientific reports 8 (1), 9873, 2018
502018
Superoxide dismutase SOD-1 modulates C. elegans pathogen avoidance behavior
AM Horspool, HC Chang
Scientific reports 7 (1), 45128, 2017
372017
Intranasal administration of BReC-CoV-2 COVID-19 vaccine protects K18-hACE2 mice against lethal SARS-CoV-2 challenge
TY Wong, KS Lee, BP Russ, AM Horspool, J Kang, MT Winters, ...
npj Vaccines 7 (1), 36, 2022
302022
Interplay of antibody and cytokine production reveals CXCL13 as a potential novel biomarker of lethal SARS-CoV-2 infection
AM Horspool, T Kieffer, BP Russ, MA DeJong, MA Wolf, JM Karakiozis, ...
Msphere 6 (1), 10.1128/msphere. 01324-20, 2021
302021
SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice
KS Lee, TY Wong, BP Russ, AM Horspool, OA Miller, NA Rader, JP Givi, ...
PloS one 17 (8), e0273430, 2022
282022
Neuron-specific regulation of superoxide dismutase amid pathogen-induced gut dysbiosis
AM Horspool, HC Chang
Redox biology 17, 377-385, 2018
202018
SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy
AM Horspool, C Ye, TY Wong, BP Russ, KS Lee, MT Winters, JR Bevere, ...
BioRxiv, 2021.05. 05.442784, 2021
192021
Defining the mechanistic correlates of protection conferred by whole-cell vaccination against Pseudomonas aeruginosa acute murine pneumonia
E Sen-Kilic, CB Blackwood, AB Huckaby, AM Horspool, KL Weaver, ...
Infection and Immunity 89 (2), 2021
162021
Human Liver Microsomes Immobilized on Magnetizable Beads: A Novel Approach to Study In Vitro Drug Metabolism
AM Horspool, T Wang, YS Scaringella, ME Taub, TS Chan
Drug Metabolism and Disposition 48 (8), 645-654, 2020
142020
Reinvestigating the Coughing Rat Model of Pertussis To Understand Bordetella pertussis Pathogenesis
JM Hall, J Kang, SM Kenney, TY Wong, GJ Bitzer, CO Kelly, CA Kisamore, ...
Infection and immunity 89 (12), 2021
132021
Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice
TY Wong, AM Horspool, BP Russ, C Ye, KS Lee, MT Winters, JR Bevere, ...
Journal of Virology 96 (6), e02184-21, 2022
122022
Long-Term Analysis of Pertussis Vaccine Immunity to Identify Potential Markers of Vaccine-Induced Memory Associated With Whole Cell But Not Acellular Pertussis Immunization in Mice
KL Weaver, CB Blackwood, AM Horspool, GM Pyles, E Sen-Kilic, ...
Frontiers in Immunology 13, 838504, 2022
92022
Obesity and metabolic dysfunction drive sex-associated differential disease profiles in hACE2-mice challenged with SARS-CoV-2
KS Lee, BP Russ, TY Wong, AM Horspool, MT Winters, M Barbier, ...
IScience 25 (10), 2022
82022
Reciprocal cross-species induction of outer membrane vesicle biogenesis via secreted factors. Sci Rep 8: 9873
AM Horspool, JW Schertzer
82018
Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection. mSphere. 2021; 6
AM Horspool, T Kieffer, BP Russ, MA DeJong, MA Wolf, JM Karakiozis, ...
Feb 6 (1), 10.1128, 0
6
Development of an anti-Pseudomonas aeruginosa therapeutic monoclonal antibody WVDC-5244
AM Horspool, E Sen-Kilic, AC Malkowski, SL Breslow, M Mateu-Borras, ...
Frontiers in Cellular and Infection Microbiology 13, 1117844, 2023
32023
Diet induced obesity and type 2 diabetes drives exacerbated sex-associated disease profiles in K18-hACE2-mice challenged with SARS-CoV-2
K Lee, B Russ, T Wong, AM Horspool, MT Winters, M Barbier, JR Bevere, ...
bioRxiv, 2022.04. 26.489580, 2022
22022
Long-term analysis of pertussis vaccine immunity uncovers a memory B cell response to whole cell pertussis immunization that is absent from acellular immunized mice
KL Weaver, CB Blackwood, AM Horspool, GM Pyles, E Sen-Kilic, ...
bioRxiv, 2021.10. 01.462695, 2021
22021
Matrixed CDR grafting: A neoclassical framework for antibody humanization and developability
P Gupta, AM Horspool, G Trivedi, G Moretti, A Datar, ZF Huang, J Chiecko, ...
Journal of Biological Chemistry 300 (1), 2024
2024
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